Gene Information

Name : hsdM (LSL_0919)
Accession : YP_535812.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : type I restriction-modification system methylation subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 946586 - 948175 bp
Length : 1590 bp
Strand : -
Note : COG0286 [V] type I restriction-modification system methyltransferase subunit

DNA sequence :
ATGGCACAAGAAGAAGTTACTTTAGAAAGATCATTAGATAATGCAGCTAATGTATTACGTTCAAAAATGGATGCTAATGA
ATATAAAAATTATACGTTAGGTACTATTTTCTATAAATATCTATCTGATAGTATGCTGTATTATGTAGCTGAATTATTGG
AAGAAAAAAATATTAGCTTAGAAGAAGCTCAGAAATTATATGAAGAAAATCAAGATGATCAGTATTTAATTGAAGAATTA
GATATTAAATTTAATTATGTGATAGAAGCTAAAAACACTTATACAAATATATTAAAATCTATAAACAATCATACCTTTCA
GGTTAGTCAATTAGGCGATGCTTTTAATAGTATTGAAAGTCAAGGAAAAGAATTTGAAGGTTTATTTGACGATTATGATT
TGTATTCTAAGCGTTTAGGAAACACTGCACAAAAGCAATCTGATACAATTTCAGAAGTACTAAGTGCAATTGGTAAATTA
GAAATTGTTAAAACTCCAGAAGACACTTTAGGAAATGCATATGAATATTTAATTAAACAATTTGCATCTGAATCAGGTAA
AAAGGCTGGTGAATTTTATACACCACAAAAAGTATCTAGATTATTAGCAAGATTAACTTTAGTCGATAAGGATTATACAG
ATGGAATGACTGTATACGATCCAACAATGGGGTCAGGTTCATTATTATTGAATTTCCGTAAATATGTGGAACATCCTAAA
AGAATTACTTATTTTGGTCAAGAAATTAATACTTCAACATATAACTTGGCGCGCATGAATATGATTTTGCACCATGTAGA
TGTTGTTAATCAAAAACTCCGAAATAATGATACTCTTGATGAAGATTGGCCAGTTGAAGAAATAACTAACTTTGATGCAG
TTGTAATGAATCCACCATATTCTCATAAGTGGTCTGCCAATGCTGGTTTTAAAGATGATCCACGTTTTTCCGCCTATGGA
GTTTTGCCGCCAAAATCTAAAGCTGACTATGCTTTCTTGTTACATGGGTATTATCATTTGAAACATAGTGGGGTAATGGC
CATTGTTTTACCTCATGGAATATTATTCAGAGGGGCAGCAGAAGGTAAAATCAGAAAGAAATTGTTAGAAAATGGGGCAA
TAGACGCGGTTATCGGTTTACCAGCTAACTTGTTCTATAACACAAGTATTCCAACTACGATTGTCGTTTTGAAGAAAGAT
AAGCAAGATCGCGATGTATTATTCATTGATGCTTCAAAAGATTTTGAAAAAGTTAAGACACAAAACGAACTACGTGACGA
AGATGTAGAAAAAATTCTTACAACATATAAAGAGCGTAAAGACATTGATAAGTATGCCCACTTAGCTAGTTTTGATGAGA
TTAAAGAAAATGAATTTAACTTAAATATTCCACGTTATGTAGACACTTTTGAGCCTGAACCAGAAATTAATTTAGATGAA
GTTTCAAAAGAATTAAGAGAAACGAATGAGAAAATCAAAGAAAATGAAATTGAATTAATTAGTATGCTAAAAGATTTAAC
TTCCAAAGATGAGAAGATTACGAAAGGCTTAAATGACTTCATAAGTGTCTTAGAAGAGGATGTGAAATAA

Protein sequence :
MAQEEVTLERSLDNAANVLRSKMDANEYKNYTLGTIFYKYLSDSMLYYVAELLEEKNISLEEAQKLYEENQDDQYLIEEL
DIKFNYVIEAKNTYTNILKSINNHTFQVSQLGDAFNSIESQGKEFEGLFDDYDLYSKRLGNTAQKQSDTISEVLSAIGKL
EIVKTPEDTLGNAYEYLIKQFASESGKKAGEFYTPQKVSRLLARLTLVDKDYTDGMTVYDPTMGSGSLLLNFRKYVEHPK
RITYFGQEINTSTYNLARMNMILHHVDVVNQKLRNNDTLDEDWPVEEITNFDAVVMNPPYSHKWSANAGFKDDPRFSAYG
VLPPKSKADYAFLLHGYYHLKHSGVMAIVLPHGILFRGAAEGKIRKKLLENGAIDAVIGLPANLFYNTSIPTTIVVLKKD
KQDRDVLFIDASKDFEKVKTQNELRDEDVEKILTTYKERKDIDKYAHLASFDEIKENEFNLNIPRYVDTFEPEPEINLDE
VSKELRETNEKIKENEIELISMLKDLTSKDEKITKGLNDFISVLEEDVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 7e-102 50
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 1e-99 48
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 3e-100 48
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 8e-100 48
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 1e-99 48
ORF6 BAC22943.1 - Not tested etd PI Protein 2e-99 48
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 6e-100 48
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-100 48
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 5e-100 48
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 8e-100 48
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-100 48
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 3e-99 48
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 4e-100 48
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 8e-100 48
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 2e-99 48
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 8e-100 48
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 1e-99 48
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 8e-100 48
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 4e-100 48
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 6e-100 48
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 4e-100 48
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 4e-100 48