Gene Information

Name : pykF (LSL_0867)
Accession : YP_535760.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 889779 - 891539 bp
Length : 1761 bp
Strand : +
Note : COG0469 [G] Pyruvate kinase

DNA sequence :
ATGAAAAAGACCAAGATCGTAAGTACCCTTGGACCAGCTAGTTCTGACCTAGATACAATTGTTAAGTTAATCGAAGCAGG
TGCAAATGTTTTCCGTTTTAATTTCTCACACGGTGATCATGAAGAACACTTAGGCCGCATGAATTTAGTTCATGAAGCTG
AAAAAATTACTGGTAAAACAGTAGGTTTCTTATTAGATACAAAGGGTGCAGAAATTCGTACAACTGTTCAAAAAGAAGGC
AAGATTCATTTTGCAATCGGTGATGAAGTACGTATTTCTATGGACGATTCTATTGAAGGTACAAAAGAAAAAATCGCTGT
AACATACCCTGGTTTATACGATGACGTTCACGAAGGTGGACATGTATTGTTTGACGACGGTTTGATTGATATGCAAATCG
AAAAGAAAGACGATGCAAACAAAGAACTTGTATGTAAAGTATTAAACGAAGGTACACTTGGTTCTCGTAAAGGTGTTAAT
GCTCCTGGTGTTTCTATCAACTTACCTGGTATTACAGAAAAAGACTCTGATGATATCCGCTTTGGTTTAGACCAAGACAT
TAACTACATTGCTGCTTCCTTCGTACGTAAGCCACAAGATATCTTAGATATTCGTGAATTACTTGAAGAAAAGCACATGG
AACATGTACAAATCTTCCCTAAGATTGAATCTCAAGAAGGTATCAACAACTTTGATGAAATCTTGAAAGTTTCTGATGGT
TTAATGATCGCTCGTGGTGACATGGGTGTTGAAATCCCAGCTGAAAATGTTCCTTTGGTACAAAAATCATTAATCAAGAA
GTGTAACTTAGCTGGTAAGCCAGTTATCACAGCTACACAAATGCTTGATTCTATGCAAGAAAACCCACGTCCTACACGTG
CTGAAGCTTCTGACGTTGCTAACGCTGTATTTGATGGTACAGATGCAACAATGCTTTCGGGTGAATCTGCAAATGGTGAC
TACCCTGTAGAATCCGTTGCTACAATGGCACGTATCGACATCAAGTCTGAAAATGCATTACGTCAACACAAAGCATTGAC
ATTGGATGCATTTGATAAGACAGACGTTACAGAAGCAATTGGTCGTTCAGTTGCTGAAACAGCAGAAAACTTGAACATTA
AGACAATTGTTGCTGCTACAAAATCTGGTCATACAGCACGTATGATTTCTAAGTACCGTCCAAATGCTGACATTTTAGCT
GTTACATTTGATGATCGTACACGTCGTGGTTTAACAGTTAACTGGGGTGTACAACCTGTATTGGCTGATGCTCCTTCATC
AACTGATGAAATGTTCCAATTAGCTACAGAAGAAGCTAAGAAGGCTGGTTTAGCTAAGGAAGGCGACTTGATCTTAATCG
TTGCTGGTGTTCCTGTAGGTGAAAAAGGCACTACAAACATCATGAAGATCCAATTAATTGGTTCTAAGTTAGTTTCAGGT
CAAGGTGTTGGTGATGAAACTGTTATCGGTAAGACAGTTGTTGCAACATCTGCTGATGAAGCAAACAAGAACGCTGTTGA
AGGTGGAATCCTTGTAACAAAGACAACTGACAAAGATTACTTACCAGCTATTGAAAAATCATCTGCTTTAATCGTTGAAA
ATGGTGGTTTAACATCTCATGCAGCTGTAGTAGGTATTTCTATGGGTATTCCTGTAGTTGTTGGTGCTAAGGATGCAACA
TCATTGATCAAGAGCGGTGAAGTTGTAACAGTTGATAGCCGTCGTGGTATTGTATACCATGGTGCATCAAACGCTCTTTA
A

Protein sequence :
MKKTKIVSTLGPASSDLDTIVKLIEAGANVFRFNFSHGDHEEHLGRMNLVHEAEKITGKTVGFLLDTKGAEIRTTVQKEG
KIHFAIGDEVRISMDDSIEGTKEKIAVTYPGLYDDVHEGGHVLFDDGLIDMQIEKKDDANKELVCKVLNEGTLGSRKGVN
APGVSINLPGITEKDSDDIRFGLDQDINYIAASFVRKPQDILDIRELLEEKHMEHVQIFPKIESQEGINNFDEILKVSDG
LMIARGDMGVEIPAENVPLVQKSLIKKCNLAGKPVITATQMLDSMQENPRPTRAEASDVANAVFDGTDATMLSGESANGD
YPVESVATMARIDIKSENALRQHKALTLDAFDKTDVTEAIGRSVAETAENLNIKTIVAATKSGHTARMISKYRPNADILA
VTFDDRTRRGLTVNWGVQPVLADAPSSTDEMFQLATEEAKKAGLAKEGDLILIVAGVPVGEKGTTNIMKIQLIGSKLVSG
QGVGDETVIGKTVVATSADEANKNAVEGGILVTKTTDKDYLPAIEKSSALIVENGGLTSHAAVVGISMGIPVVVGAKDAT
SLIKSGEVVTVDSRRGIVYHGASNAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-98 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-98 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-98 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-98 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_535760.1 pyruvate kinase VFG0479 Protein 1e-98 49