Gene Information

Name : clpL (LSL_0059)
Accession : YP_534963.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 67810 - 69918 bp
Length : 2109 bp
Strand : +
Note : COG0542 [O] ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATAACACACCTTTTGATAACTTTAATAATATGGATGATATTTTTAATGAATTGATGGGAAGTATGAATGGTATTAA
TTCTGAACGTCGTTATTTAATTAATGGTCGTGAAGTGACCCCAGAAGAATTTGCTCAATATCGTAAGACCGGAAAATTAC
CAAATAATAATCAAATGACCAGTCAAGGCAAAGCTCCAAATAAAGATGGAATTTTAGCTAAATTAGGACGTAACTTAACT
CAAGAAGCTCGTGAAGGCAAGTTAGATCCAGTTATTGGACGTAACAAAGAAATTCAAGAGACTGCTGAAATTTTAGCACG
TCGTACGAAGAACAATCCTGTTCTAGTAGGGGATGCTGGTGTTGGTAAGACAGCAGTTGTTGAAGGCTTGGCACAAGCAA
TTGTGAATGGCGATGTACCTGCTTCAATTAAGAATAAAGAAATTATCAGTATTGATATCTCTGGCTTAGAAGCTGGTACA
CAATATCGTGGTAGCTTTGAAGAAAATATTCAAAACTTAATTAAGGAAGTTAAAGATAGAGGAAATGTGATCCTATTCTT
TGATGAAATCCATCAAATCTTAGGTGCTGGTGGTATGGGCGGTGACAACGGCTCTAAAGGTTTAGCTGATATTTTGAAAC
CAGCTTTATCTAGAGGTGAAATCACAGTTATTGGTGCTACAACTCAAGATGAATATCGTAATACCATTATGAAGAACGCA
GCTTTGGCACGTCGATTCAATCAAGTTACGGTAAATGCTCCAAGTCCAGAAGATACATTTAAGATTTTACAAGGTATCAG
AAACTTGTACGAAAAGCATCACAATGTTGTATTGCCAGATAATGTTTTAAAGGCTGCTGTGGACTACTCAATTCAATATA
TACCACAAAGAAGTTTGCCAGATAAAGCTATTGATTTGATAGATATGACGGCTGCACATCTTGCTGCAAAGCATCCTGTT
ACAGATGTTAAAGAATTAGAAAATCAAATTAAAGATGAAAAAGAAAAGCAACAAGCAGCTGCTGACAAGGAAGATTATGA
AGCAGCTTTAAATGCTAAGACAAAGATTGAAGAATTGCAAAAGAAGATTGATAACCATTCTGAATCTCAAAAAGTAACAG
CTACAGTTAATGATGTTGCTGAAGCCGTAGAACGTTTGACAGGTATTCCTGTATCCAAGATGGGTGCTAGTGATATCGAA
CGCTTAAAGGAAATCGGCAAGAGATTAAAGGGCAAAGTTATTGGTCAAGATGAAGCTGTAAATGCAGTAGCTCGTGCTAT
CCGTCGTAATCGTGCTGGTTTTGACGAAGGAAATCGCCCAATCGGTAGCTTCTTATTCGTTGGACCAACTGGGGTCGGAA
AGACAGAATTAGCTAAGCAATTAGCTTTGGATATGTTTGGCTCTAAAGATGCGATTATTCGTTTGGATATGTCAGAATAT
TCTGATAGAACTGCCGTATCTAAATTGATTGGTACAACAGCTGGTTATGTAGGTTATGACGACAATAGTAACACTTTGAC
TGAACGTGTACGTCGTAATCCATATTCAATTATCTTGCTAGATGAAATTGAAAAAGCTGACCCACAAGTAATCACATTAT
TACTTCAAGTATTAGATGACGGTCGTTTAACTGATGGTCAAGGTAATACTATTGACTTCAAGAATACAGTTATTATCGCA
ACATCTAACGCTGGTTTTGGTAACGAAGATTTAATGGGCAAAGACGAAAAAGAAGACAAGGACATTATGAAGAAGATTGC
TCCTTACTTCCGTCCAGAATTCTTGAATCGTTTCAATGCCGTAATTGAATTCTCACATTTGACTAAGGAAGATTTGAAAG
AAATTATTGATTTGATGTTAGACGAAGTAAACAAGACTTTGGCTAAGAAAGGTCTTGACTTGGTAGTAACTGATGCTGCT
AAGAACTATCTTATCGAACAAGGTTACGATGAAGCAATGGGTGCTCGTCCATTACGTCGTGTCATTGAACAACAAATTCG
TGATAAAGTAACAGACTTCTACTTGGATAATGTAGATGTAAAACATTTATTAGCTGATATGAAAGATGGCGAATTAGTAA
TCAGTGAAAGAAAGGATGCAGATAAATAA

Protein sequence :
MNNTPFDNFNNMDDIFNELMGSMNGINSERRYLINGREVTPEEFAQYRKTGKLPNNNQMTSQGKAPNKDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIKNKEIISIDISGLEAGT
QYRGSFEENIQNLIKEVKDRGNVILFFDEIHQILGAGGMGGDNGSKGLADILKPALSRGEITVIGATTQDEYRNTIMKNA
ALARRFNQVTVNAPSPEDTFKILQGIRNLYEKHHNVVLPDNVLKAAVDYSIQYIPQRSLPDKAIDLIDMTAAHLAAKHPV
TDVKELENQIKDEKEKQQAAADKEDYEAALNAKTKIEELQKKIDNHSESQKVTATVNDVAEAVERLTGIPVSKMGASDIE
RLKEIGKRLKGKVIGQDEAVNAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTIDFKNTVIIA
TSNAGFGNEDLMGKDEKEDKDIMKKIAPYFRPEFLNRFNAVIEFSHLTKEDLKEIIDLMLDEVNKTLAKKGLDLVVTDAA
KNYLIEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDNVDVKHLLADMKDGELVISERKDADK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-130 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_534963.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 1e-142 49
clpL YP_534963.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 2e-134 45