Gene Information

Name : leuS (LSL_0442)
Accession : YP_535335.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 488667 - 491084 bp
Length : 2418 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCATATAAGCATATTGAAATAGAAAAAAAGTGGCAAAGATATTGGGAAGAACACAAAACATTCAAAACAACTGAAGA
TGATGATAAAAAGAATTATTATGCCTTAGATATGTTTCCATATCCATCTGGGCAAGGACTTCATGTAGGTCATCCTGAAG
GGTATACAGCTACAGATATAATGGCTCGTATGAAGAGAATGCAAGGATATAATGTTTTACACCCAATGGGATGGGATGCA
TTCGGTTTACCTGCTGAACAATATGCGTTGAATACAGGCAACTCACCACGTGAATTTACTAAAAAAAATGTTAATAATTT
TAGACGTCAAATTAAATCTTTAGGTTTATCATATGATTGGGATCGAGAAGTTAACACTACTGATCCTGCATATTATAAAT
GGACTCAATGGATTTTTGAACAATTATATAAAAAAGGTTTAGCCTATGAAGCTGAAGTTCCAGTTAACTGGAGTCCAGAT
TTAGGAACTGTTGTAGCTAACGAAGAAGTTATTGATGGTAAAACTGAACGTGGTGGTTTTCCTGTTATTAGAAAACCAAT
GCGTCAATGGGTATTAAAAATCACGGCTTATGCTGATCGCTTAATAGATGATTTAGACGATTTAGATTGGCCAGAAGCAA
TTAAAGAACAACAACGTAATTGGATTGGTCGTTCAGTTGGTGCAGCAATAAACTTTCCTGTTTCAGGAGATGAAAATACA
AAGATTGAGGTATTTTCTACTCGTCCAGATACAATATTTGGTGTTGCAGCTTTAGTATTGGCACCTGAACATGAATTGGT
TAAGCAATTAACAACTCCTGAACATGAAAATGAGGTAGAAGCATACATAGAAAAAATATCTCATAAATCAGATTTAGAAA
GAACAGATTTAGCTAAAGATAAAACAGGTGTATTTACAGGTAGTTATGTTGTAAATCCTGTAAGTGGAGAAAAATTACCT
ATTTGGATTGCTGATTATGTTTTAAATTCATATGGAACAGGTGCGGTAATGGTTGTTCCTGCACATGATGAACGAGATCA
TGAATTTGCTCAAAAGTTTGATTTGCCTATCGTACAAGTTATCGAAGGTGGAGATGTTCAAAAAGAAGCATATACTGGTG
ATGGAGTTCATATCAATTCTGATTTCCTAAATGGCATGGATAAAGAAGAAGCCATTGATGCTATAAATAACTGGCTAGAG
GAAAATGGAGTAGGGGAAAAGAAAGTTAACTATCGTTTAAGAGATTGGTTATTCTCTAGACAACGTTACTGGGGCGAGCC
TATTCCTGTAATTCATTGGGAAGATGGTGAAACAACTCTAGTTCCAGAAGATGAATTACCTTTATATTTACCTAAAGCAA
CAGATATTAAGCCTTCAGGAACTGGTGAAAGTCCATTAGCTAACTTAGATGATTGGGTAAATGTTGTTGATGAAAATGGT
AGAAAAGGACGTCGTGAAACTAATACTATGCCACAATGGGCTGGTAGTTCCTGGTACTTCCTACGTTATATAGATCCACA
TAACAATCATGAAATAGCAGATTATGAAAAATTAAAAGAATGGTTACCTGTAAACTTGTATGTTGGTGGTGCTGAACACG
CTGTATTACATTTATTGTATGCTCGTTTCTGGCATAAATTCTTATATGATTTAGGTGTAGTTCCAACTAAAGAACCATTC
CAAAAATTGGTAAACCAAGGAATGATTTTAGGTTCTAATCATGAAAAGATGTCCAAGTCTAAAGGAAATGTAGTTAATCC
AGATGATATTGTTGAACAATATGGAGCAGATACATTACGCTTATATGAAATGTTTATGGGGCCTTTAGATGCATCTATTC
CTTGGAGTGAAGAAGGACTTGGTGGCGCACATAAGTTCATCAACCGTGTTTGGAATTTATTGATTGATGAAAATGACAAT
TTGCGTGATAGAGTAACTACAATTAACAATCATGATTTAGATAAGATATATAATGAAACTGTTAAGAAAGTTACAGAAGA
CTATGAGGCTATGCACTTTAATACTGCAATTTCCCAATTAATGGTCTTTGTTAATAATGCTTATAAAGCAGATTCATTAC
CATTGGAATATGTAGAAGGCTTAGTAAAATTGTTATCACCAGTTGTTCCTCATATTACAGAAGAATTATGGTCTAAGTTA
GGTCATGTAGGTAGCATAGCATATGCTAAGTGGCCAACCTATGATGAAAGCAAGTTGGTTGAAGATGTTGTAGAAATTGT
TGTTCAAATTAACGGTAAAGTAAGACAACATCTACAAGTATCTAAAGATGCTAGTCGTGAAGAATTACAAGCACTAGCTT
TGAACGACGAAAGAATAAAACAAGAACTTGCGGATAAAGAAGTTAAAAAAGTTATTGCAGTTCCTGGTAAGTTAGTATCA
ATTGTAGTAGCAAAATAA

Protein sequence :
MSYKHIEIEKKWQRYWEEHKTFKTTEDDDKKNYYALDMFPYPSGQGLHVGHPEGYTATDIMARMKRMQGYNVLHPMGWDA
FGLPAEQYALNTGNSPREFTKKNVNNFRRQIKSLGLSYDWDREVNTTDPAYYKWTQWIFEQLYKKGLAYEAEVPVNWSPD
LGTVVANEEVIDGKTERGGFPVIRKPMRQWVLKITAYADRLIDDLDDLDWPEAIKEQQRNWIGRSVGAAINFPVSGDENT
KIEVFSTRPDTIFGVAALVLAPEHELVKQLTTPEHENEVEAYIEKISHKSDLERTDLAKDKTGVFTGSYVVNPVSGEKLP
IWIADYVLNSYGTGAVMVVPAHDERDHEFAQKFDLPIVQVIEGGDVQKEAYTGDGVHINSDFLNGMDKEEAIDAINNWLE
ENGVGEKKVNYRLRDWLFSRQRYWGEPIPVIHWEDGETTLVPEDELPLYLPKATDIKPSGTGESPLANLDDWVNVVDENG
RKGRRETNTMPQWAGSSWYFLRYIDPHNNHEIADYEKLKEWLPVNLYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPF
QKLVNQGMILGSNHEKMSKSKGNVVNPDDIVEQYGADTLRLYEMFMGPLDASIPWSEEGLGGAHKFINRVWNLLIDENDN
LRDRVTTINNHDLDKIYNETVKKVTEDYEAMHFNTAISQLMVFVNNAYKADSLPLEYVEGLVKLLSPVVPHITEELWSKL
GHVGSIAYAKWPTYDESKLVEDVVEIVVQINGKVRQHLQVSKDASREELQALALNDERIKQELADKEVKKVIAVPGKLVS
IVVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65