Gene Information

Name : clpE (LSL_0386)
Accession : YP_535279.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 423785 - 425977 bp
Length : 2193 bp
Strand : -
Note : COG0542 [O] ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTATGCCAAAATTGTCATAAAAATCCTGCGACAATTCACTTAACAACTAATTTAAACGGTCGCCAAACCTCTATTGA
TCTTTGTCAAAATTGTTACCAAGAAATCAAAAATGAAGCTAACGGCTTTAATAATATTGGACAAGATCCATTTGGTTTTG
GTAGTTTAGATGATATTTTCAAAGCTATATCCAATCCTAATTTTTCTAACCAACAAAGCATGTCTCAAGAACCACCTACA
CAAAATAGTCGCATAGGTGGAAATAACGGTAATCGCAACGGTGATTCATCTATTCTGGGACAATATGGATTAGATTTAAC
AGAAGAAGCAAAAAATGGTCAAATCGATCCAGTTATTGGACGTGATAAAGAAATAGCCAGAGTAATTGAAATTCTAAATA
GACGCACTAAAAATAATCCTGTTTTAATCGGTGAAGCTGGTGTTGGTAAAACTGCTGTTGTTGAAGGACTCGCACAAAAA
ATTGTTAATGGCGATGTTCCTCAAAAACTAATCGGGAAAAAAGTTATTCGTCTAGATGTTGTTTCTTTAGTACAAGGAAC
TGGTATCCGTGGACAATTTGAACAAAGAATGCAACAACTAATGAAAGAATTGAAACAACAAAAAGATGTAATCTTATTTA
TTGATGAAATTCATGAAATTGTTGGTGCTGGTAATGCAGAAGGTGGAATGGATGCTGGTAATGTACTCAAACCATCTCTT
GCTCGTGGAGAATTCCAATTAGTAGGTGCTACTACCCTAAATGAATTCAGAACAATTGAAAAAGATGCCGCACTTGCTCG
TCGTCTTCAACCAGTTCAAGTTGATGAACCTAGTGTAGAAGAAACTATTAAAATTCTAAATGGTATTCGTAATAAATATG
AAGCTTATCATCATGTAAAATATACTGATGAAGCTTTAAGGGCTGCTGTAACTTTATCTAATAGATATATTCAAGATAGA
TTCTTACCTGATAAAGCAATTGATTTATTAGATGAATCTGGGTCTCGTAAGAATTTAACAATTCATGCAACTGATCCAAA
AATTATTGAAGAACGCATTAAGAATGCCGAAAATCAAAAACAAGCTGCACTAAAAGAAGAAAATTATGAAAAAGCTGCTT
ACTATCGTGATCAAGTATCACGTTTTGAAAAGATGAAAGACAATGCTTCAGATAAAGATACTCCGGTTGTTACCGAAAAA
GATATGGAACATATTATAGAAGAAAAAACTAACATTCCTGTTGGTGAATTAAAAGCTAAGGAAAAGGAACAACTTCGTGA
TTTAGGCTCTTCACTTGAAAAACATGTTATTGGTCAAGATGAAGCTGTAGATAAGGTTGCTCGTTCAATTCGAAGAAATC
GTATAGGTTTCAACAAATCAGGACGTCCAATTGGTTCATTCTTATTCGTTGGTCCTACTGGTGTAGGTAAAACTGAAACA
GCTAAGCAATTAGCCCGCGAGTTATTTGGTACTGAAGACTCAATGATTCGATTTGACATGAGTGAATACATGGAAAAATT
CTCAGTTTCTAAATTAATCGGTTCTCCTCCTGGATATGTCGGCTATGAAGAAGCTGGTCAATTAACTGAACAAGTTCGCC
GTCATCCTTATAGCTTAATTTTACTTGATGAAGTTGAAAAAGCTCATCCTGATGTAATGCATATGTTCTTACAAATCCTT
GATGATGGTCGTCTAACCGATTCCCAAGGAAGAACAGTTTCATTTAAAGATACTATCATTATTATGACAAGTAATGCTGG
TAGTGGTGATTCTGTAGTATCAGTTGGTTTTGGAGCTGAAGCAAATGGTTCATCTCATTCAGTTATTGATAAATTAACCA
AGTACTTTAAGCCTGAATTCTTAAATCGTTTTGATGATATCATTGAATTTAATCCATTGTCTAAAGATAATTTAGTCAAA
ATCGTCCGATTAATGCTAGATGATGTTAATAAAATGATGGCTGATCAAAATATGCACATTGATGTTAGTGATAAAGTCGC
AGATAAACTTGCAGAATTAGGTTATGATCCTAAGATGGGCGCTAGACCACTTCGTCGTGTAATTCAAGAACAAATTGAGG
ATAAAATTGCTGATTTTTATCTTGATAATCCAAATGTTCAAAATTTTGTTGCTGATCTAGATGAAAATGGTGATATCGTA
ATTAAATCTAAGTCTGAAAAAAATGAAGACTAA

Protein sequence :
MLCQNCHKNPATIHLTTNLNGRQTSIDLCQNCYQEIKNEANGFNNIGQDPFGFGSLDDIFKAISNPNFSNQQSMSQEPPT
QNSRIGGNNGNRNGDSSILGQYGLDLTEEAKNGQIDPVIGRDKEIARVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQK
IVNGDVPQKLIGKKVIRLDVVSLVQGTGIRGQFEQRMQQLMKELKQQKDVILFIDEIHEIVGAGNAEGGMDAGNVLKPSL
ARGEFQLVGATTLNEFRTIEKDAALARRLQPVQVDEPSVEETIKILNGIRNKYEAYHHVKYTDEALRAAVTLSNRYIQDR
FLPDKAIDLLDESGSRKNLTIHATDPKIIEERIKNAENQKQAALKEENYEKAAYYRDQVSRFEKMKDNASDKDTPVVTEK
DMEHIIEEKTNIPVGELKAKEKEQLRDLGSSLEKHVIGQDEAVDKVARSIRRNRIGFNKSGRPIGSFLFVGPTGVGKTET
AKQLARELFGTEDSMIRFDMSEYMEKFSVSKLIGSPPGYVGYEEAGQLTEQVRRHPYSLILLDEVEKAHPDVMHMFLQIL
DDGRLTDSQGRTVSFKDTIIIMTSNAGSGDSVVSVGFGAEANGSSHSVIDKLTKYFKPEFLNRFDDIIEFNPLSKDNLVK
IVRLMLDDVNKMMADQNMHIDVSDKVADKLAELGYDPKMGARPLRRVIQEQIEDKIADFYLDNPNVQNFVADLDENGDIV
IKSKSEKNED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-147 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_535279.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 0.0 60
clpE YP_535279.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 2e-152 51