Gene Information

Name : clpC (LSL_0196)
Accession : YP_535094.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 232289 - 234781 bp
Length : 2493 bp
Strand : +
Note : COG0542 [O] ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGCTATGGAAGAAAGGTATACACCGAGTGCTAAACAAGTATTAGTTCTTGCACAACAACAAGCTAATTACTTCAAGCA
TCAAGCAATAGGAACAGAACATTTGCTTTTAGCACTAACAATGGAGAAAAATGGCGTAGCTGCTAAAGTATTACAAAGTT
TTGTAGTAACTGAAGTAGATGTGCGAGAAGAAATTGAACATATCGTAGGATACGGTAATTTACAACGTAGAGGCGCTGAT
ACTTATTTACCATATTCCCCAAGAACTCGTTATGTATTAGAGCGTGCTAGAGAACATGCTAAACTTTTTAATGTTGAAAA
GGTAGGAACAGAACATATTTTGTTAGCACTATTAGAAGATGATAAAACTATTTCTTCACGTATTCTAGCAGCTCTGAATA
TTGATTTACGTAAGGTGAAAAATATTACCTATCGTACAATGGGTGTAGATGCAACAACAGCTAATAGAACACGTAAGAAA
TTAGCGTTATCAGAAAAGAAACAGGATAATGGTACACCTACGTTAGATGAATTAGCGCGTGATTTGACAGAAATGGTGCG
TAAAGATCAAATTGATCCAGTAGTTGGTAGAGATAATGAAATTAAGCGTGTTGTTCAAATTTTAAGTAGAAGGACAAAGA
ATAATCCAGTTCTTTTGGGAGAACCAGGTGTAGGTAAAACAGCTGTTGCAGAAGGATTTTCACAAAAGATTGTAAATGGT
GAAGTTCCTGATAATTTAAAGAATAAGCGTGTAATGATGCTTGATATGGGATCTTTGGTTGCTGGAACAAAATATCGTGG
TGAATTTGAAGATCGATTAAAGAAGATTATTGAAGAAATTCGTGAAGATGGCAATGTTATTTTATTCATTGATGAAATGC
ATACTCTAATAGGTGCGGGTGGTGCTGAAGGCGCGATAGATGCTTCCAATATTTTAAAACCAGCATTAGCGCGTGGTGAA
GTACAAGTAATAGGTGCAACAACTTTAAATGAATATCAAAAATATGTTGAAGCTGATGCAGCTTTGGAAAGACGCTTTGC
TAGTGTGACAATTAATGAACCCACTCCAGAAGTAGCGTTGACAATTCTAAAAGGATTACGTCCTAAATATGAAAAACACC
ATCAACTTCAAATTACAGATGAGGCATTAGAGAGTGCAGTTAAGTTAAGTAAAAGATATATTGCTTCAAGATTTTTACCT
GACAAGGCAATTGATTTAATGGATGAGGCTGCTGCTAGAGTAAGAATTAATAATGCACAAAAAGTGGACAAAGTTTCTGC
AATAAAGAAGAAATTATCAGAGCTTTCCCAAGAGAAGACAGAAGCGTTGTTAAAAGAAGATTTTGAAAAAGCTGCAGAAA
TCAGAAATGAAGAATTAAAGATTCAAGAAAAGCTTGAAAAGCAAATCCAACGTGACAAAGATGAAGAGGATAGCAATAAC
TATCGTGTAAAAGTTACGGCTGAAGATATTGCAGAAGTTGTTTCTGAATGGACTGGTGTTCCAGTAACTCAAATTAATCG
TTCTGAAGGAGACCGACTAATTAGATTAGAAAAGATATTGCATAATCGAGTTATAGGACAAGATGAAGCTGTTAAAGCAG
TAAGTAAAGCGATAAGAAGAGCAAGAAGTGGTTTGAAGGATCCTACAAGACCAATTGGCTCATTTATGTTCTTAGGTCCT
ACAGGTGTAGGTAAAACTGAATTAGCTAAAGCTTTAGCAGAAGCTATGTTTGGCTCAGAGGATTCAATGATTAGAATTGA
TATGAGTGAATATATGGAGAAATACACAACTAGTCGTTTAATTGGATCTCCTCCTGGATACGTAGGATATGATGAAGGCG
GACAATTAACTGAAAAGGTTAGAAATAATCCTTATTCAGTAGTATTATTAGATGAAGTTGAAAAAGCTCATAATGATGTT
TTCAATATCTTGTTACAAGTATTAGATGATGGATTTTTAACTGATTCTAAAGGTAGAAAGGTAGACTTCAGAAATACAAT
TATCATTATGACATCTAACTTAGGTGCTACAGCCTTACGCGATGAAAAATCAGTAGGTTTTGGTGCAAAAGATGTCAGCG
ATGATTATGAAGCAATGGCAGCAAAAGTTAGAGAAACATTGAAGAAGACTTTTAGACCAGAGTTCTTGAATCGTCTTGAC
GAAATTGTTGTATTCCATTCGCTTAATAAAGAAGAAATTCATCAAATTGTTAAATTGATGGCTAAGAATATTATAGATAG
GATTAAAGAACAAAATATTAATCTGAAAATTACCCCTGCAGCAATAGATATAGTTGCAGAAGCTGGATTTGATGCTGAAT
ATGGTGCTCGTCCTATTAGACGTATCCTTCAAGATAAGATAGAGGACTTACTAAGTGAAGAATTATTAGCAGGTAATATC
GAAACTGGAGCAACAGTAACAATAGGTGCTAAAAAAGGTGAAATAACGATAAAAGTTAAGAATCCAGTAGCTGCAGAAAA
AATAAATAGTTAA

Protein sequence :
MAMEERYTPSAKQVLVLAQQQANYFKHQAIGTEHLLLALTMEKNGVAAKVLQSFVVTEVDVREEIEHIVGYGNLQRRGAD
TYLPYSPRTRYVLERAREHAKLFNVEKVGTEHILLALLEDDKTISSRILAALNIDLRKVKNITYRTMGVDATTANRTRKK
LALSEKKQDNGTPTLDELARDLTEMVRKDQIDPVVGRDNEIKRVVQILSRRTKNNPVLLGEPGVGKTAVAEGFSQKIVNG
EVPDNLKNKRVMMLDMGSLVAGTKYRGEFEDRLKKIIEEIREDGNVILFIDEMHTLIGAGGAEGAIDASNILKPALARGE
VQVIGATTLNEYQKYVEADAALERRFASVTINEPTPEVALTILKGLRPKYEKHHQLQITDEALESAVKLSKRYIASRFLP
DKAIDLMDEAAARVRINNAQKVDKVSAIKKKLSELSQEKTEALLKEDFEKAAEIRNEELKIQEKLEKQIQRDKDEEDSNN
YRVKVTAEDIAEVVSEWTGVPVTQINRSEGDRLIRLEKILHNRVIGQDEAVKAVSKAIRRARSGLKDPTRPIGSFMFLGP
TGVGKTELAKALAEAMFGSEDSMIRIDMSEYMEKYTTSRLIGSPPGYVGYDEGGQLTEKVRNNPYSVVLLDEVEKAHNDV
FNILLQVLDDGFLTDSKGRKVDFRNTIIIMTSNLGATALRDEKSVGFGAKDVSDDYEAMAAKVRETLKKTFRPEFLNRLD
EIVVFHSLNKEEIHQIVKLMAKNIIDRIKEQNINLKITPAAIDIVAEAGFDAEYGARPIRRILQDKIEDLLSEELLAGNI
ETGATVTIGAKKGEITIKVKNPVAAEKINS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_535094.1 negative regulator of genetic competence VFG0079 Protein 0.0 57
clpC YP_535094.1 negative regulator of genetic competence VFG0080 Protein 2e-158 49