Gene Information

Name : serS (LSL_0189)
Accession : YP_535087.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 215973 - 217250 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATATTAAAGATATTCGATTAAATACAGAAGAATATAAACGTCGCTTGGGAACAAGAGGCGTAAAACCAGAAGA
AATTGATGAATTAGTAGCTGAAGACAAGAAACGTAGAGAGTTACTTGTTGAAACTGAAAATTTAAAGAAAGAACGTAATG
AAGTTTCTGAAGCTATTGCTCAAGCAAAACGAAACAAAGAAGATGCTAGTGAACAAATTCAAGCAATGCGTAAAGTTGGT
ACTAAGATCAAAGAACTTGATGAAAAACTAGCTAAAGTAGAAGAAAATGTAAAATCTATGGCTGCTCACTTGCCTAACTT
ACCAAATCCTACTATTCCAGTAGGACCAGATGAAGATTCAAATGTTGAACTTTATAAAGTAGGGACACCACGTAAGTTTG
ATTTTGAACCTAAAGCACACTGGGATATTGGTGAAGACCTAGGAATTTTAGATTTCGATCGCGCAGCTAAAGTTTCTGGG
GCAAGATTTGTTTTCTATAAAGGATTAGGAGCAAAACTTGAACGTGCGGTTTATAACTTTATGTTAGATGAACATGCTAA
AGAAGGTTATACAGAAGTAATTCCTCCATATATTGTTAAATCTAAATCAATGTATGGAACTGGTCAATTCCCTAAATTTA
AGGACCAAGTATATCAAGTTAATGGGGAAGATATGACTTTAATTCCAACAGCTGAAGTACCTTTAACTAACTATTATCGT
GAAGAAGTAATCCCAACAGAAGACTTACCAGTTTACTTTACAGCTTTATCACCATCCTTCCGCTCTGAAGCAGGAAGTGC
AGGTCGAGATACTCGTGGCTTGATACGTATGCACCAATTTAATAAAGTTGAAATGGTTAAATATACTAAGCCAGAAGATT
CATATAATGAATTGGAAAAAATGACAAAAAATGCTGGTAACATTATGGAAAAACTAGGATTACCATATCATGTAATTACT
CTATCTACTGGAGATATGGGATTCAGTGCAGCTATGACACATGACTTAGAAGTATGGATGCCAGCACAAGATACTTATAG
AGAAATCTCAAGCTGTTCTAATTGTGAAGATTTCCAAGCTAGAAGAGCAAGAATTCAATATCGTGATGAAAATGGTAAAC
TACAATATGTTCATACATTAAATGGCTCTGGTTTAGCTGTAGGTAGAACTGTAGCTGCTATTTTAGAAAACTACCAAAAT
GAAGATGGATCAGTAACAATTCCAGAAGCATTACGTCCATATATGCAAGGTTTAGAAGTTATCAAGAAAGAAAAATAA

Protein sequence :
MLDIKDIRLNTEEYKRRLGTRGVKPEEIDELVAEDKKRRELLVETENLKKERNEVSEAIAQAKRNKEDASEQIQAMRKVG
TKIKELDEKLAKVEENVKSMAAHLPNLPNPTIPVGPDEDSNVELYKVGTPRKFDFEPKAHWDIGEDLGILDFDRAAKVSG
ARFVFYKGLGAKLERAVYNFMLDEHAKEGYTEVIPPYIVKSKSMYGTGQFPKFKDQVYQVNGEDMTLIPTAEVPLTNYYR
EEVIPTEDLPVYFTALSPSFRSEAGSAGRDTRGLIRMHQFNKVEMVKYTKPEDSYNELEKMTKNAGNIMEKLGLPYHVIT
LSTGDMGFSAAMTHDLEVWMPAQDTYREISSCSNCEDFQARRARIQYRDENGKLQYVHTLNGSGLAVGRTVAAILENYQN
EDGSVTIPEALRPYMQGLEVIKKEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-146 68