Gene Information

Name : nrdF (LSL_1233)
Accession : YP_536124.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1266599 - 1267579 bp
Length : 981 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACTAAATCATATACCGCTATTAATTGGAATGCTTTAGAAGATGAAATTGATAAGGCTACGTGGGAAAAACTTACTGA
ACAATTCTGGTTAGATACACGTATTCCTTTATCCAATGACTTATCTGATTGGCGTGAATTTAATGAAGATGACAAAGACG
TCGTTGGTAAAGTATTCGGTGGTTTAACTTTATTAGATACACTTCAATCCCAAGATGGTATGTCTTCATTGAAGAAAGAT
GTTCGTACGCAACACGAAGAAGCTGTTATGAATAACATTGAATTTATGGAATCAGTTCATGCTAAAAGTTATTCTTCAAT
TTTTTCTACATTAAACACTCCTAAGGAAATTGAAGAAATCTTTGATTGGACAAATTCTAATGAAATCTTGCAATATAAAG
CTAATCGTATCAATGAAATTTATCAAAACGGTAGTCCTTTACAAAAGAAAGTTGCTTCTGTATTTTTAGAAACATTTTTA
TTTTATTCAGGATTCTATACTCCACTATATTGGTTAGGTCATAATAAATTAGCAAACGTAGCAGAAATTATTAAACTAAT
TCTTCGCGATGAATCGGTTCATGGTACTTACATTGGATATAAGTTTCAATTAGGCTTTAATGAACTATCTGATGATGAAC
AAGAAGAATTTACTTCTTGGATGTACGATTTGCTTTATGAGTTATACGAAAATGAAGAAAAATATACTCACTTACTTTAT
GACAAAGTTGGTTGGACTGATGATGTATTAGTTTTCCTTCGTTACAATGCTAATAAAGCATTAATGAACTTAGGTATGGA
TCCACTATTTGCTGATGGATATGCGCAAAATGTTAATCCAGTCGTTATGAATGGTATTTCAACTTCTACATCTAACCATG
ACTTCTTCTCCCAAGTTGGTAATGGATATCTCCTTGGTGACGTTGAAGCAATGGAAGATTCTGATTACTTATTTAACTTT
GATGATAACTCTGATAAATAG

Protein sequence :
MTKSYTAINWNALEDEIDKATWEKLTEQFWLDTRIPLSNDLSDWREFNEDDKDVVGKVFGGLTLLDTLQSQDGMSSLKKD
VRTQHEEAVMNNIEFMESVHAKSYSSIFSTLNTPKEIEEIFDWTNSNEILQYKANRINEIYQNGSPLQKKVASVFLETFL
FYSGFYTPLYWLGHNKLANVAEIIKLILRDESVHGTYIGYKFQLGFNELSDDEQEEFTSWMYDLLYELYENEEKYTHLLY
DKVGWTDDVLVFLRYNANKALMNLGMDPLFADGYAQNVNPVVMNGISTSTSNHDFFSQVGNGYLLGDVEAMEDSDYLFNF
DDNSDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-67 48