Gene Information

Name : nrdA (LSL_1232)
Accession : YP_536123.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1264410 - 1266581 bp
Length : 2172 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGAGTCTAAAGGACATTGATATTAGTAAAGTTACTTACTTTGATTTAAATAATGAAATAAATATTCCTGTAAATGGTCA
AATCCAATTAGGAAAAGATGAAGAGGCTCTTGAAGCCTTTTTAAATGAAAATGTTAAGCCTAATACTAAACAATTTTCTT
CAATTAAGGAACGAATTAATTATTTAATTCAAAATAACTACTATGAAGAAGAATTTATTTCTAAATATTCATTTGAATTT
ATCGAAAAATTATATGATTACCTAAAAAAAGAAGATTTTCATTTTAAAACTTTTATGGCAGCATATAAATTTTATGCTCA
ATATGCCTTAAAAACTGACGATAATGCCTACTATTTAGAAAACTTTATAGATAGAGTCGCTACTAACGCTCTTTATTTTG
GTGATGGAGATGAAAAATTAGCTTTAGAATTAGCCGATGAATTAATCCATCAAAGATATCAACCTGCTACTCCAAGTTTC
TTGAATGCCGGTCGTAAACGCCGTGGAGAACTGGTATCTTGTTTCTTAATCCAAATGACTGATGACATGAATTCAATCGG
AAGAAATATTAATTCTGCCCTACAATTATCACGTATTGGCGGTGGTGTTGGTATTAATCTTTCTAATTTACGTGGTGCTG
GTGCTCCTATTAAAGGAATTCATGGAGCTGCATCTGGTGTCGTTCCTGTTATGAAGTTACTTGAAGATAGCTTTACATAT
TCAAACCAACTTGGTCAACGTCAAGGTGCTGGTGCTGTTTATTTAAATGTCTTCCATCCTGATATAGAAGCATTTTTATC
TGCTAAAAAAGAAAATGCTGATGAAAAAATTCGTGTAAAGACCCTTTCATTAGGATTAGTCGTTCCAGATAAATACTACG
AATTAGTAGCTAAAAATGAAGATATGTATCTTTTTGATCCTTGGGGAGTTGAACGTGTTTACCACAAACCATTTTCTTAT
GTGGATATTACTAAAGAATATGATAATATGGTTGCTAATCCAAATATCCCTAAGAAAGTTATCAAAGCTCGTGATTTGGA
AGAACAAATATCTAAGCTACAACAAGAATCTGGTTATCCTTATGTTATTAACATAGATACTGCTAACAGAGTAAATCCTA
TTTCTGGAAAGATTGTCATGAGTAATCTATGTTCCGAAATTTTACAAGTTCAACGTGCTTCAGTAATTAATAATCGTCAA
GAATATGAAGTTCTGGGGACAGATATTAGCTGTAACTTAGGTTCTACTAATATTGTAAACCTTATGGCATCACCTAACTT
CGGTAAATCTGTTGAAGTTATGACTAGAGCTTTAACTTTTGTTACTGATAAATCAGATATTGATGTTGTTCCATCAATCC
AACACGGAAATCGATTAGCTCATACTATCGGTTTAGGTGCTATGGGGTTACACGCTTACCTTGCTAAGAATCAAATTGAA
TACGGATCACCCGAAGCTCTTGAATTTACTAGTGTATATTTCATGTTACTAAACTATTGGACTTTAGTAGCTTCAAACAA
AATTGCAAAAGAAAGAAAAGTTACTTTTGATAATTTTGAAAATAGTAAATATGCTGACGGTCGTTACTTTGATACTTATT
TAAATCAAGAATTTGCACCAAAAAATGCACGTGTTAAAGAATTATTTGATGGTATCTTTATACCTACAAAATCCGACTGG
ACTAGTCTTAAAGAAAATGTTATGAAGTACGGCTTATATCATCAAAACAGATTAGCTGTAGCACCTAATGGCTCTATTTC
ATATATTAATGACACAACAGCTAGTCTACACCCTATCATCAATAGAATTGAAGAACGTCAAGAAAGAAAAATTGGAAAGA
TTTACTATCCTGCACCTTACTTGTCAAATGAAACTTTACCTTATTACAAATCAGCATACGATACTGATATGCGTAAAGTT
ATCGATACTTATGCAGCAGCTCAACAACATGTTGATCAAGGTATGAGTTTAACATTATTTATGCGTTCAACAATTCCAGC
AGGTTTATATGAATGGAAGAATGGAAGAACTGATAAAATGACAACTAGAGATTTATCTATTCTTCGCAATTATGCACATT
ATAAGGGTGTTAAATCTATTTACTATGTACGTACTTTTACTGATGATGCATCTGAAGTTGGTGCAAATGAATGCGAAAGT
TGTTCAATTTAG

Protein sequence :
MSLKDIDISKVTYFDLNNEINIPVNGQIQLGKDEEALEAFLNENVKPNTKQFSSIKERINYLIQNNYYEEEFISKYSFEF
IEKLYDYLKKEDFHFKTFMAAYKFYAQYALKTDDNAYYLENFIDRVATNALYFGDGDEKLALELADELIHQRYQPATPSF
LNAGRKRRGELVSCFLIQMTDDMNSIGRNINSALQLSRIGGGVGINLSNLRGAGAPIKGIHGAASGVVPVMKLLEDSFTY
SNQLGQRQGAGAVYLNVFHPDIEAFLSAKKENADEKIRVKTLSLGLVVPDKYYELVAKNEDMYLFDPWGVERVYHKPFSY
VDITKEYDNMVANPNIPKKVIKARDLEEQISKLQQESGYPYVINIDTANRVNPISGKIVMSNLCSEILQVQRASVINNRQ
EYEVLGTDISCNLGSTNIVNLMASPNFGKSVEVMTRALTFVTDKSDIDVVPSIQHGNRLAHTIGLGAMGLHAYLAKNQIE
YGSPEALEFTSVYFMLLNYWTLVASNKIAKERKVTFDNFENSKYADGRYFDTYLNQEFAPKNARVKELFDGIFIPTKSDW
TSLKENVMKYGLYHQNRLAVAPNGSISYINDTTASLHPIINRIEERQERKIGKIYYPAPYLSNETLPYYKSAYDTDMRKV
IDTYAAAQQHVDQGMSLTLFMRSTIPAGLYEWKNGRTDKMTTRDLSILRNYAHYKGVKSIYYVRTFTDDASEVGANECES
CSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 3e-177 53