Gene Information

Name : secA (LSL_1186)
Accession : YP_536077.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1223594 - 1225957 bp
Length : 2364 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATCTTCTTAAACGTTGGGTGGAAAGTGATAAACGAGAGCTTAAACGCCTAGGAAAAATTGCTGATAAGGTAGA
ATCATATGCTGATGAATTTGGTGCTTTATCAGATGATGAATTAAAAGCAAAAACAGAAGAATTTAAAAAAAGATATCAAG
ATGGAGAAAGCTTAGATGATTTATTACCTGAAGCTTTTGCTGTCTGCCGAGAAGGTGCAAAAAGGGTACTAGGCTTGTAT
CCATACCATGTTCAAATAATTGGTGGTATCGTTTTGCATGAAGGTAATATTGCAGAAATGAAAACAGGTGAAGGTAAAAC
TTTGACTGCTACAATGCCAGTATATTTGAATGCTATTTCTGGTAAAGGTGTTCATGTTGTTACTGTTAACGAATATTTAT
CTGAACGTGATGCCACAGAAATGGGAGAGTTATACACATGGTTAGGGCTAACTGTTGGTTTGAACTTAGCTGATAAATCA
CCAGAAGAAAAGCGTAATGCTTATAATTGTGATATTACTTATTCAACTAATAGTGAACTTGGTTTTGATTATTTGCGTGA
TAACATGGTTGTTTACAAGGAAGATATGGTTCAACGTCCATTGAATTTTGTTATCGTAGACGAAGTTGACTCTATTTTAA
TTGATGAAGCTAGAACACCATTGATTATTTCTGGTCAAGCAACAGGAACGACAACTCTTTATACTAGAACTGATCGTTTT
GCTAAGACTTTGACAGAAGATGAAGATTTCAAGATTGATTTGGAATCAAAGACAGTTTCATTGACAGAAGATGGTATCCG
TAAAGGTGAAAAATATTTTGGATTAAAGAACTTATATGACCCAGATAATATGGCACTAAACCATCATTTGGATAATGCTC
TACGTGCTAATTACATCATGTTAAGAGATAAAGATTATGTTGTACGTGATGGTGAAGTTCTAATTGTTGATCAATTTACT
GGACGTATTATGGATGGACGTCGTTATTCTGACGGATTACACCAAGCTATTGAAGCAAAAGAACATGTTGAAATTGAAGA
AGAAACAAAGACAATGGCTAACATTACTTATCAGAACTTCTTCAGAATGTATAATAAACTTTCTGGAATGACAGGTACAG
CTAAGACAGAACGTGAAGAATTCCGTGAAATTTATAATATGGAAGTTGTATCTATTCCTACAAACAAACCAATTGCTCGT
GTAGACAAGCCTGATTTGTTATATCCTACACTAAAGAGTAAATTTAATGCAGTAGTAAGAGATGTAAAAGCACGTCATGA
AAAAGGACAACCTGTTTTAGTAGGTACAGTTGCAGTTGAAACTTCTGAATTATTGTCTAAGATGTTAGACGATGAAGGCA
TACCACATTCTGTTTTAAATGCTAAAAATCATGCTCGTGAAGCTGAAATTGTAATGAATGCTGGTCAACGTGGTGCGGTA
ACAATTGCTACTAACATGGCTGGTCGTGGTACTGATATCAAACTTGGACCTGGTGTTCGTGAATTAGGTGGATTAGCTGT
TATTGGTACTGAACGTCATGAATCGCGAAGAATTGATAATCAGTTACGTGGACGTTCAGGTCGTCAAGGAGATCCAGGTG
TTACTCAGTTCTATCTATCATTAGAAGACGATTTAATGTTGCGTTTTGGATCGGAACGCATTAAGAACTTCTTGGAAAGA
ATGAAAGTTAGTGATGACGATGCAGTTATTCAATCTAAGATGATAAGTCGTCAAGTAGAATCAGCACAAAAACGTGTTGA
AGGTAATAACTATGATACTCGTAAGCAAGTTCTTCAATATGATGATGTTATGAGAGCTCAACGTGAAGTTATTTATGCTC
AAAGACAACAAGTAATTATGGAAGAAAAGAGCTTGAAACCAATAATTATGCCTATGATTGAAAGAACTGTAAAGCATACA
GTTTTGATGCATACTCAAGGTGATAAGAGTGAATGGAATTTGCAAGGTATTTTAGATTTTGCTGTTTCTGCAATGGTTAA
TGAAGACACTATTAGTTTAGGTGATTTGGTAAATAAAACACCAGATGAAATTGTTGACTATTTAATGAAACGTGCAGAAG
ATATCTATGCTGAAAAAGAAAAGCAATTGTATGATGAAAGTCAAATGTTAGAATTTGAAAAAGTTGTAATTCTAAGAGTT
GTTGACTCATTGTGGACAGATCATATTGATGAAATGGACCAATTAAGACAATCTATTGGTTTGCGTGGATATGGACAATT
AAATCCATTGGTAGAATATCAACAAGATGGTTTCAGAATGTTTGAACAAATGGTAGGTGCAATCGAATATGATGTTACTC
GTTTGTTCTTGAAAGCTGAAATTAGACAAGACATAAAGCGATAA

Protein sequence :
MANLLKRWVESDKRELKRLGKIADKVESYADEFGALSDDELKAKTEEFKKRYQDGESLDDLLPEAFAVCREGAKRVLGLY
PYHVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNAISGKGVHVVTVNEYLSERDATEMGELYTWLGLTVGLNLADKS
PEEKRNAYNCDITYSTNSELGFDYLRDNMVVYKEDMVQRPLNFVIVDEVDSILIDEARTPLIISGQATGTTTLYTRTDRF
AKTLTEDEDFKIDLESKTVSLTEDGIRKGEKYFGLKNLYDPDNMALNHHLDNALRANYIMLRDKDYVVRDGEVLIVDQFT
GRIMDGRRYSDGLHQAIEAKEHVEIEEETKTMANITYQNFFRMYNKLSGMTGTAKTEREEFREIYNMEVVSIPTNKPIAR
VDKPDLLYPTLKSKFNAVVRDVKARHEKGQPVLVGTVAVETSELLSKMLDDEGIPHSVLNAKNHAREAEIVMNAGQRGAV
TIATNMAGRGTDIKLGPGVRELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSLEDDLMLRFGSERIKNFLER
MKVSDDDAVIQSKMISRQVESAQKRVEGNNYDTRKQVLQYDDVMRAQREVIYAQRQQVIMEEKSLKPIIMPMIERTVKHT
VLMHTQGDKSEWNLQGILDFAVSAMVNEDTISLGDLVNKTPDEIVDYLMKRAEDIYAEKEKQLYDESQMLEFEKVVILRV
VDSLWTDHIDEMDQLRQSIGLRGYGQLNPLVEYQQDGFRMFEQMVGAIEYDVTRLFLKAEIRQDIKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 6e-146 43