Gene Information

Name : LSL_0995 (LSL_0995)
Accession : YP_535886.1
Strain : Lactobacillus salivarius UCC118
Genome accession: NC_007929
Putative virulence/resistance : Virulence
Product : UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : 1.1.1.-
Position : 1012569 - 1014458 bp
Length : 1890 bp
Strand : -
Note : COG1086 [MG] Predicted nucleoside-diphosphate sugar epimerases

DNA sequence :
ATGAATTCTATCAACAAGATAAAATCACTTCCTCAATGGGTGTTTCGAGCATTCTACCTATCTTTGTATGACTTGATAAC
AGTCAATTTTGCTTATTTTATAGTGTTATGGTTACACTATAATTTGAGATACACAACCATCCCCTTAAAGTATTTACAAG
CATATCTAAGTTTTGTACCAGTATACTCTTTATTTACTTTGAGTGTTTTCTATTTTTTGAAATTATATAAGAGTATTTGG
AAATACGTTAGTCTGAGTGAAATGAACCGAATATTATTAGCGACAATTGTAACAGCGATTTTTCATGGAATCGGTATTAC
CGTTTTATGCACAAGAATGCCTATTTCCTATTATTTAATGGGACCGCTATTTCAATTTATGTTTACCGTGAGTGTAAGGT
TTGCATATCGTTTTATTAATTTAGTGAGAAGACGAAAACAAAGAAATGAAAATGCTAAATATAATTCTTTAATTATTGGA
GCTGGTTCAGCAGGTCAAATTATTATTAAAGAACTAGAAAATTCATCAGTAGCACAATCTGTTCCTAAATGTGTAATTGA
TGATGATCCAAACAAATGGGGTAGAATGTTGAAAAATATTCCAATTATAGGTGGACGTGAGAAAATCATTGAAGCAGTTC
AAAAATTTGATATCACACAAATTATTTTTACAATACCTTCTGCAAGTGCTAAAGATAAAAGAGAGATTTTGAATATCTGT
AAGGAAACGGATTGTAAGTTATTGACATTGCCAGGAGTGTATCAATTATTAAACGAAGAAGTTTTCTTACAGCATTTAAA
GCCAGTAGCGGTTGAAGATTTATTAGGAAGAGAACCAATAAAGGCAGATTTAGGCCAAATCAAGAAACAAATTCAAGGTA
AAGTTGTATTAATAACTGGTGGTGGAGGCTCAATTGGTTCAGAGCTTTGTCGTCAGATTGCGACCTATGATCCTAAGCAA
TTAATCGTTTTTGATATCTATGAGAATAATGCTTATAGTATTGAACAAGAATTAAAAAGAAACTATCCTAATTTAAATTT
AAAAGTTTTAATTGGATCAGTTCGAGATCAAAAAAGAGTAGATGATATTTTTTCGAGTTATCGACCAGATATTGTTTATC
ACGCTGCTGCCCATAAGCATGTTCCATTAATGGAAGGTAGTCCTAATGAAGCAGTTAAAAACAATGTTGTTGGTACTTAT
AACACTTCTAAGGCAGCCTTAAAGTACAATGCTGAACGATTTGTACTAATTAGTACAGATAAGGCAGTTAATCCAACAAA
TGCAATGGGAGCTAGCAAGCGTATTTGTGAGATGATTATTCAAATGATGGATAAAGACAGTCGCAATAGAAAGAAACGAA
CACAGTTTGTAGCAGTTAGATTTGGAAATGTTCTAGGCAGTAATGGTTCTGTGATTCCTTTATTCAAGAAACAAATTGCA
GCCGGTGGTCCAGTTACAGTAACTCATCCTGATATTATTCGATATTTCATGACGATTTCAGAAGCAGTTGGGTTGGTTTT
GCAAGCCGGAGCATATGCGGCTGGTGGAGAAATATTTGTTTTAGATATGGGACAACCAATTAAAATTGATACTTTAGCAC
GAAACTTAATTAAGTTATCAGGATTGCATCCAGATGAAGATATCGAAATTAAATATATTGGTTTGCGTCCAGGAGAAAAA
CTATATGAAGAAAAGTTAATGGCTGAAGAAGGATTACAAAAGACAGAAAATCAACTTATCTATATTGGAAAACCAATTCC
ATTTGATGAGAAAAAATTCTTAAAAAATTTACAGAATCTAATTCAAAGTAGTCAAGAAAATCCTAAGAATATTGAAGCTC
AGATGCAAAAAATTGTACCGAACTTCAAGTTTCAGGAGGTGGTAGGATGA

Protein sequence :
MNSINKIKSLPQWVFRAFYLSLYDLITVNFAYFIVLWLHYNLRYTTIPLKYLQAYLSFVPVYSLFTLSVFYFLKLYKSIW
KYVSLSEMNRILLATIVTAIFHGIGITVLCTRMPISYYLMGPLFQFMFTVSVRFAYRFINLVRRRKQRNENAKYNSLIIG
AGSAGQIIIKELENSSVAQSVPKCVIDDDPNKWGRMLKNIPIIGGREKIIEAVQKFDITQIIFTIPSASAKDKREILNIC
KETDCKLLTLPGVYQLLNEEVFLQHLKPVAVEDLLGREPIKADLGQIKKQIQGKVVLITGGGGSIGSELCRQIATYDPKQ
LIVFDIYENNAYSIEQELKRNYPNLNLKVLIGSVRDQKRVDDIFSSYRPDIVYHAAAHKHVPLMEGSPNEAVKNNVVGTY
NTSKAALKYNAERFVLISTDKAVNPTNAMGASKRICEMIIQMMDKDSRNRKKRTQFVAVRFGNVLGSNGSVIPLFKKQIA
AGGPVTVTHPDIIRYFMTISEAVGLVLQAGAYAAGGEIFVLDMGQPIKIDTLARNLIKLSGLHPDEDIEIKYIGLRPGEK
LYEEKLMAEEGLQKTENQLIYIGKPIPFDEKKFLKNLQNLIQSSQENPKNIEAQMQKIVPNFKFQEVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 9e-87 45
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 6e-87 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LSL_0995 YP_535886.1 UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase VFG1300 Protein 3e-88 42