Gene Information

Name : guaA (RPC_3063)
Accession : YP_532926.1
Strain : Rhodopseudomonas palustris BisB18
Genome accession: NC_007925
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3395511 - 3397118 bp
Length : 1608 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGCACCCAGCAAAACCTCCGCTTCGCCCGTCGATCCGTCGCCGCATGTCGCCGCGGCGCATGACAAGATCCTGAT
CGTCGATTTCGGCTCCCAGGTGACGCAGCTGATCGCGCGACGGGTGCGCGAAGAGGGCGTCTATTCCGAGATCGTGCCGT
TCAACAAGGCCGAAGCCGCCTTTGCTGCGATGAAGCCGAAGGCGGTGATCCTGTCCGGCGGCCCAGCCTCGGTGCTGGAC
GACGATGCCCCGCAAGCGCCGCTATCGATCCTCACCGCCGGCGTGCCGATCCTCGGCATCTGCTACGGCGAGCAGACGCT
GGCCAAGCAGCTCGGCGGCATCGTGGAAGGCGGCCATCACCGCGAATTCGGCCGCGCCCAGATCGAGATCACCGACGATT
GCGCGCTGTTCGACGGCGTCTGGGAGAAGGGCGGAAAATACGACGTCTGGATGAGCCATGGCGACCGCGTCACGCAATTG
CCGGAGGGTTTCCGCGGCGTGGCGAAGGCGGCGGGCTCGCCGATCTCGGTGATCGCCGACGACGCTCGCAAGTTCTACGC
CATGCAGTTTCACCCCGAGGTGGTGCACACCCCGGACGGCGCCAAGCTGATCCGCAACTTCGTGCGCAAGGTCGCAGGCC
TCAAGGGCGACTGGACCATGCGTGCGTTTCGCGAGGAGGCGATCGAGAAGATCCGCGCCCAGGTCGGCAGCGGCAAGGTG
ATCTGCGGGCTTTCCGGCGGCGTTGATAGCGCGGTTGCCGCGGTGCTGATCCATGAGGCGATCGGCGATCAGCTGACGTG
CGTGTTCGTCGACCACGGCCTGCTGCGCAAGGACGAGGGCAAGACCGTCGTCGACCTGTTCCGCCACCACTACAACATCC
CCTTGGTGCATGTGGACGCCGCCAAACTGTTTCTCGGCGAACTCGAGGGCGTCAGCGATCCGGAATTGAAGCGCAAGACC
ATCGGCCGGCTGTTCATCAACGTGTTCGAAGGCGAGGCCAAGATGATCGGCGGCGCCGATTTCCTGGCGCAAGGAACCCT
CTATCCCGACGTGATCGAGAGCGTGTCGTTCACCGGCGGCCCGTCGGTGACGATCAAGTCACACCACAATGTCGGCGGCC
TGCCGGAACGCATGAACATGCAGCTGGTCGAGCCGCTGCGCGAATTGTTCAAGGACGAGGTGCGCGTGCTCGGCCGCGAA
CTCGGGCTTCCCGAAGTGTTCGTCGGCCGCCATCCGTTCCCCGGACCTGGCCTTGCGATCCGCTGCCCCGGCGAGATCAC
CGCGGAGAAGCTGGAGATTTTGCGCAACGCCGACGCGGTCTATATCGACCAGATCCGCAAGGCCGGACTCTACGACAAAA
TCTGGCAGGCCTTCGCGGTGCTACTCCCCGTCAAGACCGTCGGCGTGATGGGCGACGGCCGCACCTATGAATACGTCGTC
GGGCTGCGCGCGGTGACCTCGACCGACGGCATGACCGCGGACTTCTACGGCTTCGAGATGAGCTTCCTCGGCGCCGCCGC
GACCCGGATCATCAACGAGGTCAAGGGCGTCAACCGCGTGGTGTATGATATCACGAGCAAGCCGCCGGGGACGATTGAGT
GGGAATGA

Protein sequence :
MTAPSKTSASPVDPSPHVAAAHDKILIVDFGSQVTQLIARRVREEGVYSEIVPFNKAEAAFAAMKPKAVILSGGPASVLD
DDAPQAPLSILTAGVPILGICYGEQTLAKQLGGIVEGGHHREFGRAQIEITDDCALFDGVWEKGGKYDVWMSHGDRVTQL
PEGFRGVAKAAGSPISVIADDARKFYAMQFHPEVVHTPDGAKLIRNFVRKVAGLKGDWTMRAFREEAIEKIRAQVGSGKV
ICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRKDEGKTVVDLFRHHYNIPLVHVDAAKLFLGELEGVSDPELKRKT
IGRLFINVFEGEAKMIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRE
LGLPEVFVGRHPFPGPGLAIRCPGEITAEKLEILRNADAVYIDQIRKAGLYDKIWQAFAVLLPVKTVGVMGDGRTYEYVV
GLRAVTSTDGMTADFYGFEMSFLGAAATRIINEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-128 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-128 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-128 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-117 50