Gene Information

Name : guaA (Rfer_2287)
Accession : YP_523536.1
Strain : Rhodoferax ferrireducens T118
Genome accession: NC_007908
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2510652 - 2512262 bp
Length : 1611 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCATCAAAAAATTCTCATTCTTGACTTTGGCTCCCAGGTCACCCAGTTGATTGCGCGGCGCATCCGCGAGGCGCATGT
GTTTTGCGAAGTGCATCCCTGTGATGTGACTGATGACTGGGTGCGTGCCTATGCCCGGGATGGCAAGCTCAAAGGCGTGA
TCCTGTCGGGCAGCCATGCCAGCGTCTATGAAGAGACGACCGACAAGGCGCCGCCTGCGGTGTTTGAACTGGGTGTGCCG
GTGCTGGGCATTTGTTATGGCATGCAGACCATGGCGCACCAGTTGGGCGGCATCGTCACCAGCGGGCACCAGCGCGAGTT
TGGCCCCGCCGATGTGCGCGCCCATGGCCATACCGCCTTGCTTGAAGGTATTCAGGACTACAAGACGGCCGCGGGCCACG
GCATGCTGCAGGTCTGGATGAGTCATGGCGACAAGGTCACCGAGTTGCCGCATGGCTTCAAGCTGATGGCCAGCACCGAC
AGTTGCCCGATCGCCGGCATGGCCGATGAAACGCGGCGTTTTTATGGTGTGCAGTTTCACCCTGAGGTGACGCACACCAA
GCGCGGTGCGGCGATTCTGGAGCGCTTTGTGCTCGATATTTGTGGCGCACGGGCTGACTGGATCATGGGCGATTACATCA
GCGAGGCGGTGGAGCAAATCCGCGCCCAGGTCGGCACCGACGAGGTCATTTTGGGCCTCTCCGGTGGGGTCGATTCGTCG
GTCGCTGCGGCCCTGATCCACCGGGCCATTGGTGAGCAACTCACCTGCGTGTTTGTGGACCACGGCCTGCTGCGTCTCAA
CGAGGGCGACCTGGTGATGGAAATGTTTGTCGGCAAGCTGCACGCCAAGGTGATTCGGGTTGATGCTGCTGACCAGTTCC
TCGGACAGCTCGCGGGCGTGAGCGACCCGGAGGCCAAACGCAAAATTATTGGCCGCGAGTTTGTCGAAGTGTTCAAGGCC
GAGGCTGCCAAGCTCAAAAGCGACCAGTCGCGCCACGTCGCCTGGCTGGCCCAGGGCACGATTTACCCCGACGTGATCGA
ATCCGGCGGCGCCAAGAACAAAAAAGCGGTGGTCATCAAAAGCCACCATAACGTGGGCGGCTTGCCGGAGCTATTGGGCC
TAAAGCTGCTGGAACCCCTGCGCGAATTGTTCAAGGATGAAGTACGCGAGCTCGGCGTGGCGCTTGGTTTGCCCTATCAC
ATGGTGTACCGGCATCCGTTTCCCGGTCCCGGTCTGGGGGTGCGGATTCTGGGCGAAGTCAAAAAGGACTACGCAGATTT
GCTGCGCCGTGCCGATGCCATCTTTATCGACGAACTGCACAACTTCATCGACGAGGCATCAGGCAAGAGCTGGTACGACC
TCACCAGTCAGGCCTTCGCGGTGTTTTTGCCCGTCAAGAGTGTCGGCGTCATGGGCGACGGCCGCACCTACGACTACGTG
GTCGCCTTGCGTGCCGTGCAAACCAGTGACTTCATGACCGCCGATTGGGCCGAGTTGCCTTATGCGCTGCTGAAAAAAGT
GTCGAGCCGCATCATCAACGAAGTGCGCGGCATCAACCGGGTCACATACGACGTGTCAAGCAAGCCGCCGGCCACCATTG
AGTGGGAGTAG

Protein sequence :
MHQKILILDFGSQVTQLIARRIREAHVFCEVHPCDVTDDWVRAYARDGKLKGVILSGSHASVYEETTDKAPPAVFELGVP
VLGICYGMQTMAHQLGGIVTSGHQREFGPADVRAHGHTALLEGIQDYKTAAGHGMLQVWMSHGDKVTELPHGFKLMASTD
SCPIAGMADETRRFYGVQFHPEVTHTKRGAAILERFVLDICGARADWIMGDYISEAVEQIRAQVGTDEVILGLSGGVDSS
VAAALIHRAIGEQLTCVFVDHGLLRLNEGDLVMEMFVGKLHAKVIRVDAADQFLGQLAGVSDPEAKRKIIGREFVEVFKA
EAAKLKSDQSRHVAWLAQGTIYPDVIESGGAKNKKAVVIKSHHNVGGLPELLGLKLLEPLRELFKDEVRELGVALGLPYH
MVYRHPFPGPGLGVRILGEVKKDYADLLRRADAIFIDELHNFIDEASGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYV
VALRAVQTSDFMTADWAELPYALLKKVSSRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-115 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-115 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-115 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-105 47