Gene Information

Name : serS (DSY0008)
Accession : YP_516241.1
Strain : Desulfitobacterium hafniense Y51
Genome accession: NC_007907
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 9380 - 10645 bp
Length : 1266 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATCTCAAATTTGTACGCACGAACCCCGAAGTAGTCAAGGAAGCCCTTAAAAAAAGAAATTCCAATGTCAGTTT
GGATGCTTTTCTGGAACAAGAAGAAGAGCGCCGCAAGCTTCTTTTTGAAGTGGAATCATTAAAAGCCAAGCGAAACACGG
TCTCTGAAGAGGTAGGGCGCCGGAAAAAACATGGGGAAGATGCGGAGCAGCTTATTTTAGAGATGCGGGAAGTGGGACAA
AAAGTTAAGAATCTCGAAGATAAATTAGGTGAGATTGAGCAGAGCATGGAAGCTGTGCTTTATGAGATTCCTAATATTCC
TCATGAATCAGTTCCAGTAGGAGCTGATGAAGAGGCCAATGTTGAGGTTCGCACTTGGGGAACTCCCCGCTCCTTTGATT
TTGAGCCTTTAGCTCATTATGAGATCGGCGAAAAGCTGGATATCCTGGATTTTGCCCGGGCAGGGAAGGTTACAGGAGCT
CGCTTTACTTTTTATAAAGGTTTAGGGGCCAAGCTGGAAAGAGCCCTGATCAGCTTCATGCTGGACCGGCATAGCGCTAA
AGGATATGTGGAAGTTCTGCCTCCTTATATGGTTCATCGTAATTCTATGATTGGTACCGGGCAGCTTCCTAAGTTTGAAG
AAGATGCTTTTAAGGTGGCGGGAACCGATTATTTCTTAATCCCTACTGCCGAAGTTCCGGTCACCAATATGTATCGGGAA
GAAATCCTGGAAGCCGAGCAATTGCCGATTCATCACTGTGCCTATAGTGCTTGTTTCCGTGCGGAAGCAGGTTCGGCAGG
CCGGGATACCCGGGGGCTCATCCGGCAGCATCAATTTAATAAAGTGGAACTGGTGAAGTTTGCCTTTCCTGAAAATTCCT
ATGAGGAGCTGGAGTCCTTAACCCGGGATGCGGAGAGTATTCTCCAGGAGCTTGAGCTTCCCTATCGGGTGATGGCTTTA
TCCACGGGGGATCTGGGCTTTACTTCAGCCAAGACTTACGATCTGGAAGTATGGCTGCCCAGCTTTAATACCTACCGGGA
GATTTCTTCCTGCAGCAATTTTGAAGATTTCCAAGCCCGCCGGGCTAATATTCGCTTCCGCCGGGCACCGAAAGCCAAAC
CTGAGTTTCTCCATACTCTCAATGGCAGTGGTTTAGCCATCGGCCGCACAGTTTCCGCTATTCTTGAAAATTATCAGGAA
GCCGACGGCAGAGTGAGAGTTCCTAAAGCACTCCAGCCTTATTTGGGTGTCGAGTACATCGGCTAG

Protein sequence :
MLDLKFVRTNPEVVKEALKKRNSNVSLDAFLEQEEERRKLLFEVESLKAKRNTVSEEVGRRKKHGEDAEQLILEMREVGQ
KVKNLEDKLGEIEQSMEAVLYEIPNIPHESVPVGADEEANVEVRTWGTPRSFDFEPLAHYEIGEKLDILDFARAGKVTGA
RFTFYKGLGAKLERALISFMLDRHSAKGYVEVLPPYMVHRNSMIGTGQLPKFEEDAFKVAGTDYFLIPTAEVPVTNMYRE
EILEAEQLPIHHCAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFAFPENSYEELESLTRDAESILQELELPYRVMAL
STGDLGFTSAKTYDLEVWLPSFNTYREISSCSNFEDFQARRANIRFRRAPKAKPEFLHTLNGSGLAIGRTVSAILENYQE
ADGRVRVPKALQPYLGVEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-125 62