Gene Information

Name : guaA (DSY3938)
Accession : YP_520171.1
Strain : Desulfitobacterium hafniense Y51
Genome accession: NC_007907
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4504560 - 4506092 bp
Length : 1533 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCTCAAGAACTCGTGTTGGTTCTGGATTTTGGTGGCCAATATAATCAGCTGATTGCTCGGCGTGTCAGAGAAGCTCA
TGTGTACTCGGAGATGATATCATATAAAACACCTGTGGAGGAGATTAAAGCAAGAAACCCCAAAGGAATTATTTTTTCCG
GCGGACCTGCCAGCGTCAATCAAGAAGGGGCACCCAAGGTGGATGAGGCCATCTATGAATTAGGCATTCCTATTTTCGGT
ATTTGTTATGGTATGCAGTTGATGACGGTTCAGCTGGGTGGAAAGGTAATGCATCCCGAAGTTCGGGAATATGGCAAAGC
TATGCTCCATGTGGATCAGGCCAAGGGTCTGTGGAAAGGCCTGGGGGGAGAACGCCAATGTTGGATGAGCCACGGGGACT
CAGTCACTGAGCTTCCTGAAGGCTTCGTTATCGCCGCTCATACAGACCATACCCCGGTAGCTGCTATGACGGACGAAACA
CGTCATTTTTACGGAGTACAGTTCCATCCGGAAGTAAAGCATACTCCAGACGGGCAGGCCATGCTTAAGCACTTTTTGTT
TGATATCTGCGGATGTCATGGGGAGTGGACGATGGAGTCCTTTATCGACGCCCAAGTCAAAGCTATTCGGGAGAAAGTGG
GAGAACGGCAGGTCCTTTGCGCCCTCAGCGGCGGTGTAGACTCCTCTGTAGCAGCCGTTCTTGTTCACAAGGCCATCGGC
GACCAACTGACCTGCGTCTTTGTGGATCATGGCTTTATGCGTAAGAATGAGCCGGAACAGGTCAAGAAGATTTTTACGGA
GCAGTTCCATCTTAAGCTGATTTTTGTGGATGCCCGGGAGCGTTTTATGGCCAAGATCGGCGGAGTATCCGATCCTGAGA
CCAAACGGATCGGTATCGGCAATGAGTTCATCCGCCTTTTTGAAGATGAAGCCCGCAAATTAGGACAGATTGATTTCTTG
GTTCAAGGCACTCTCTATCCGGATATTGTGGAGAGTGGTACGGATACCGCCGAAACCATCAAGAGCCATCATAATGTGGG
CGGACTTCCTGAAGATATGCAGTTTGAGCTGATTGAGCCGTTGGATATGCTTTTTAAGGATGAGGTTCGTGAAGTAGGTG
CTGAATTAGGTATCCCCGACGAGATCGTCTGGCGGCAGCCTTTCCCCGGACCGGGACTGGCGATTCGCATTATTGGCGAG
GTTACGGAAGAAAAGCTGGACATTCTTCGGGAGGCTGATGCCGTCATCGTGGAAGAAATCCGTAATGCAGGACTCTACAA
AGAGGTATGGCAATCCTTCGCTGTACTTCCTACCATAAAAAGCGTTGGCGTCATGGGAGATGGCCGGACTTACGCCTATC
CCATCGTTGTCCGCGCCGTGACCAGCGAGGATGCCATGACGGCGGACTGGGCAAGACTTCCCTATGACCTGATGGAGAAA
ATCTCCACCCGCATCGTTAACGAAGTGAAGGGTGTCAATAGGGTAGTGTATGACATTACCTCAAAACCCCCTGGGACCAT
TGAGTGGGAGTAA

Protein sequence :
MAQELVLVLDFGGQYNQLIARRVREAHVYSEMISYKTPVEEIKARNPKGIIFSGGPASVNQEGAPKVDEAIYELGIPIFG
ICYGMQLMTVQLGGKVMHPEVREYGKAMLHVDQAKGLWKGLGGERQCWMSHGDSVTELPEGFVIAAHTDHTPVAAMTDET
RHFYGVQFHPEVKHTPDGQAMLKHFLFDICGCHGEWTMESFIDAQVKAIREKVGERQVLCALSGGVDSSVAAVLVHKAIG
DQLTCVFVDHGFMRKNEPEQVKKIFTEQFHLKLIFVDARERFMAKIGGVSDPETKRIGIGNEFIRLFEDEARKLGQIDFL
VQGTLYPDIVESGTDTAETIKSHHNVGGLPEDMQFELIEPLDMLFKDEVREVGAELGIPDEIVWRQPFPGPGLAIRIIGE
VTEEKLDILREADAVIVEEIRNAGLYKEVWQSFAVLPTIKSVGVMGDGRTYAYPIVVRAVTSEDAMTADWARLPYDLMEK
ISTRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-161 62
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-161 62
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-161 62
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-145 58