Gene Information

Name : leuS (DSY3158)
Accession : YP_519391.1
Strain : Desulfitobacterium hafniense Y51
Genome accession: NC_007907
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3574548 - 3577031 bp
Length : 2484 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGAAATATCTTTTTTCAGAGATTGAGCCTAAATGGCAAAAAAAATGGGTGGACAGAAAAGATTATCAAGCCGA
AGAGCATTCTGATAAACCCAAATTCTATGCTTTAGCGATGTTTCCTTACCCTTCCGGCAATCTTCATATGGGACATGTCC
GGAATTATTCTATAGTGGATGTCATCGCTCGCTTTAAGCGGATGAGGGGTTACAATGTTCTGCATCCCATCGGTTGGGAT
TCTTTTGGGCTGCCGGCAGAAAATGCGGCCATTAAGAATCAAACGCCGCCGGCTGAGTGGACTTGGAAAAATATCGCCAA
TATGAAAAGGCAGCTTCAGGAAATGGGAATCTCCTATGATTGGGAGCGGGAGGTTACGACCTGTCATCCCGACTATTACA
AGTTTACGCAATGGATCTTTTTAGAGTTTTACAAACATGGCTTGGTGTATAAGAAAAAAGCCGGCGTCAACTGGTGTCCT
TCTTGTGCCACCGTTCTTGCCAACGAGCAGGTGGTGGATGGAGCTTGTGAACGTTGCGACACCGCCGTTACCAAAAAAGA
TCTGGAACAATGGTTTTTTAAGATTACGGACTATGCTCAAGTGCTTTTGGATGATCTGGAAAAGCTCCCCGGCTGGCCTG
ATAAAGTGAAGACCATGCAAAAAAACTGGATTGGCCGTTCTGAAGGAGCCGAAGTGGAATTCGACCTGGAGAACCACGGG
GATAAAATTCGGGTCTATACCACCCGGGTGGATACGATTTTTGGTGTGAGCTATGTAGTGCTGGCACCGGAGCACCCTTT
GGTGCAAAAGCTGATTGCTGGTACGGAATACGAAAATGACGTGCAAGCCTTTATCGAACGGATGAAGGGGCTGAATGAAA
TCGCCCGGACTTCCACCGAAACCGAAAAAGAAGGCCTGTTTACCGGGGCCTACTGCATTAACCCCTATAGCGGAGAAAAA
GTACCCATCTGGATCGCTAACTATGTTCTTTTTGAATACGGAACAGGAGCGGTTATGGGCGTACCGGCCCATGATGAAAG
GGACTTTGAGTTCGCCGGGAAGTATAAGCTTCCCATTAAGACCGTTATCCTGCCTGAGGGAACCCCTGTGGAGGAAAAGG
ATACTCCTCTTCAAGCAGCTTTCGTTGAAGAGGGAATGATGGTGAATTCCGGCGAGTATGATGGTCTCAAGAATGTGGAG
GCCTGGGAGAAGATGTGTGATAAAGCTGAGCACGATGGCTTTGGTGAACGGAAAGTGAATTTCCGCCTCCGTGACTGGCT
TATTTCCCGTCAGCGTTACTGGGGAGCTCCCATTCCCATGATTTATTGCGATCATTGCGGAATTGTTCCTGTGCCCCAGG
ACCAACTCCCTGTCATGCTCCCGGACGATGTGGTCTTTAAAGCGGGGGAGAATCCCCTGACCACCTCGGAAAGCTTTAAA
CAAACCATCTGTCCCACCTGTGGCGGTAAGGCCCGTCGTGAAACAGACACTATGGACACTTTTATGTGCTCCTCCTGGTA
TTTCCTCCGCTATACTGATCCCCACAATGCTCAGCTCCCCTTCGCCAAAGAAGCAGCAGATCACTGGATGAATGTGGATC
AATATGTAGGTGGAGTAGAGCATGCTATTCTCCATTTGCTGTACTCGCGTTTCTTTACTAAGGCTCTGCGGGATTTTGGC
TATCTTAAAGTCGATGAGCCCTTTGCCAACCTACTCACTCAGGGGATGGTTTGCCTGGGCGGGGCTAAAATGTCCAAATC
CAAGGGTAATGTGGTAAGTCCTGAAGAAATTATTTCTAAATATGGTGCCGATACGGCCCGCCTCTTCATCCTCTTCGCAG
CTCCGCCGGAGCGGGATTTGGAATGGAACGACCAAGGGGTGGAAGGTTGCTACCGCTTCCTCAACCGGGTGTGGCGTCTG
GCGGCTCAATACGAAGAAGTCTTAAAGACTACTGGGGCAGGGGCTAATGAATTTGGCGAATTGGACAAAGCTGCCAAGGA
CATGCGCCGTCAAACCCACCAAACCATTCAAAGAGTTACTTCGGATGTGGGAGCACGCTTCAACTTCAACACAGCCGTCA
GTGCCATTATGGAATTGGTCAATGCTCTTTATCTGTACAAAGAACAGCCCCAGGTGAATTTGGCGGTGGCCCGGGAAGCC
TTGGAGAGCATTCTCATCCTGCTGGCGCCTTTTGCACCCCATATTACCGAAGAAATCTGGAGTGAATTGGGCCATGAGGA
CAGCATCCATAGCCGGGAGTGGCCGCAAGTGGATGAAGAGGCTCTGGTCCAGGAAGAGGTCACTGTGGTCCTGCAGATCA
ACGGGAAGGTTAAGGAGCGGATTCAGGTTCCGGCCCAGATTTCCGCGGCGGAATTGGAAGCACAGGTCCGGCAGCTGCCC
AGGCTTGGGGAATGGACTCAAGGCAAACAGATCCTTAAGATCGTAACGGTGCCGGGTAAGCTGGTCAATGTCGTTGTGAA
GTAG

Protein sequence :
MQEKYLFSEIEPKWQKKWVDRKDYQAEEHSDKPKFYALAMFPYPSGNLHMGHVRNYSIVDVIARFKRMRGYNVLHPIGWD
SFGLPAENAAIKNQTPPAEWTWKNIANMKRQLQEMGISYDWEREVTTCHPDYYKFTQWIFLEFYKHGLVYKKKAGVNWCP
SCATVLANEQVVDGACERCDTAVTKKDLEQWFFKITDYAQVLLDDLEKLPGWPDKVKTMQKNWIGRSEGAEVEFDLENHG
DKIRVYTTRVDTIFGVSYVVLAPEHPLVQKLIAGTEYENDVQAFIERMKGLNEIARTSTETEKEGLFTGAYCINPYSGEK
VPIWIANYVLFEYGTGAVMGVPAHDERDFEFAGKYKLPIKTVILPEGTPVEEKDTPLQAAFVEEGMMVNSGEYDGLKNVE
AWEKMCDKAEHDGFGERKVNFRLRDWLISRQRYWGAPIPMIYCDHCGIVPVPQDQLPVMLPDDVVFKAGENPLTTSESFK
QTICPTCGGKARRETDTMDTFMCSSWYFLRYTDPHNAQLPFAKEAADHWMNVDQYVGGVEHAILHLLYSRFFTKALRDFG
YLKVDEPFANLLTQGMVCLGGAKMSKSKGNVVSPEEIISKYGADTARLFILFAAPPERDLEWNDQGVEGCYRFLNRVWRL
AAQYEEVLKTTGAGANEFGELDKAAKDMRRQTHQTIQRVTSDVGARFNFNTAVSAIMELVNALYLYKEQPQVNLAVAREA
LESILILLAPFAPHITEEIWSELGHEDSIHSREWPQVDEEALVQEEVTVVLQINGKVKERIQVPAQISAAELEAQVRQLP
RLGEWTQGKQILKIVTVPGKLVNVVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-162 43