Gene Information

Name : clpB2 (CF0652)
Accession : YP_515569.1
Strain : Chlamydophila felis Fe/C-56
Genome accession: NC_007899
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp endopeptidase ATP-binding chain B
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 754972 - 757512 bp
Length : 2541 bp
Strand : +
Note : Hemolysin B, EC 3.4.21.92

DNA sequence :
ATGTTTGAGAAGTTTACTAACAGAGCAAAACAAGTCATTAAATTGGCTAAAAAAGAGGCTCAGAGGTTAAATCATAACTA
TCTAGGCACAGAGCATATACTCTTAGGCTTACTCAAACTAGGTCAGGGCGTAGCCGTAAATGTACTGCGCAACTTAGGAG
TAGATTTTGACACTGCGAAACAAGAAGTCGAGCGTCTGATCGGTTATGGACCTGAAATCCAGGTCTATGGTGATCCTGCC
CTTACTGGAAGAGTAAAAAAATCTTTTGAATCTGCAAATGAAGAAGCTGGGGTTTTAGAACATAATTACGTAGGTACTGA
ACATCTTCTCTTAGGCATCTTAAATCAAGCCGATGGAGTTGCTTTACAGGTTTTAGAAAACTTACATATTGATCCCAGAG
AAGTTCGTAAGGAAATTCTTAAGGAATTAGAAACATTCAATCTTCAACTTCCCCCATCATCATCTTCTTCTAATCCTAGA
GGAAATTCATCTTCATCCTCTAAATCTTCTTCCCTAGGTCATACTCTGGGAGGAGAAAAAAATGATAAGTTATCGGCATT
AAAAGCTTACGGTTATGATTTAACCGAAATGTTTCGTGAGTCTAAGCTTGATCCTGTCATAGGTCGTTCTACGGAAGTAG
AGCGCCTGATCCTTATCCTATGTCGCAGAAGAAAAAATAACCCTGTACTTATCGGGGAAGCTGGTGTAGGTAAAACGGCT
ATCGTTGAAGGATTAGCGCAAAAGATCATTTCCAATGAAGTTCCCGATACTTTACGCAAAAAACGTTTAATTACCCTAGA
TCTTGCCTTAATGATTGCAGGAACTAAATATCGCGGTCAATTTGAAGAACGTATCAAAGCAGTTATGGATGAAGTCCGCA
AACACGGAAACATCCTTTTATTTATCGATGAGCTACATACAATCGTAGGTGCGGGTGCTGCTGAAGGAGCTATTGATGCT
TCTAACATCTTAAAACCAGCTCTAGCACGTGGAGAAATTCAGTGTATTGGAGCCACAACAATTGATGAATACCGCAAGCA
TATTGAAAAAGATGCTGCTTTAGAACGCAGATTCCAAAAAATTATTGTGCACCCACCTAGTGTAGATGAAACTATAGAAA
TTCTACGTGGGTTAAAAAAGAAATACGAAGAGCATCATAATGTTTCTATTACAGAAGAAGCATTGAAAGCTGCGGCCACT
TTATCTGATCAGTATGTTCACGGTCGTTTCCTTCCAGACAAAGCTATTGATTTGCTTGATGAGGCTGGAGCGCGTGTACG
TGTCAATACCATGGATCAGCCTACAGAGTTAATGAAACTCGAAGCTGAGATTGAAACTACGAAGCTCGCTAAAGAGCAAG
CGATTGGCACACAAGAATACGAAAAGGCGGCAGGATTACGCGACGAAGAGAAAAAGCTTCGAGAACGTCTCTCCAACATG
AAACAAGAATGGGAAAATCACAAAGAAGAGCATCAGATTCCCGTGGATGAGGAAGCAGTTGCTCAAGTGGTCTCCTTACA
AACAGGTATTCCTTCCGCAAGGCTTACTGAAGCTGAAAGTGAAAAGTTACTTAAGTTAGAAGATACTCTACGTAAAAAAG
TCATAGGTCAAGATCAGGCAGTAGCAAGCATTTGCCGAGCTATTCGTCGTTCAAGAACTGGCATTAAAGATCCCAACCGT
CCAACAGGCTCATTCTTATTCCTAGGCCCCACTGGAGTAGGGAAAACGTTGCTAGCTCAACAGATTGCCATCGAAATGTT
TGGTGGTGAGGATGCTTTAATTCAAGTAGATATGTCTGAGTACATGGAGAAGTTCGCCGCCACCAAAATGATGGGATCGC
CTCCAGGGTACGTTGGTCACGAGGAAGGTGGTCATCTTACGGAACAAGTACGTCGTCGTCCTTACTGTGTTGTTTTATTC
GATGAGATTGAAAAAGCTCATCCCGACATTATGGACTTAATGTTGCAAATTCTAGAGCAAGGACGTCTTACAGACTCGTT
TGGTCGCAAGATTAATTTCCGTCATGCGATCATTATCATGACTTCGAACTTAGGTGCGGACTTAATTAAAAAGAGTGGGG
AAATTGGTTTTGGCACTCGATCGAATTTTGATTACAAAGTCATCCAAGAAAAAATCGAAAATGCTGTGAAGAAGCATTTA
AAACCGGAGTTTATCAACCGTTTGGATGAAAGTGTCATCTTCCGTCCTTTAGAGAAAGATGCTTTATCTCAGATTATCCA
TTTAGAAATTAATAAACTGGATTCCCGTTTGAAAAATTACCAAATGGCTTTAAGCATTCCAGATTCCGTGATTTCTTTCT
TAGTTACGAAAGGCCACTCTCCAGAAATGGGAGCACGACCCTTACGTCGAGTTATTGAGCAGTATCTTGAAGATCCTCTT
GCGGAGCTTTTGCTTAAGGAGTCTTGCCGTCAAGAAGCGAGAAAGCTTCGTGCTAGTCTCACAGAAGATCGAGTAACTTT
CGAGCGCGAGGAAGAACAATCTGAAAGTATTCCGGCAACTATACCGACTGGGGAGTCATAG

Protein sequence :
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAKQEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGVALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPR
GNSSSSSKSSSLGHTLGGEKNDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDA
SNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQKIIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAAT
LSDQYVHGRFLPDKAIDLLDEAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQAVASICRAIRRSRTGIKDPNR
PTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLF
DEIEKAHPDIMDLMLQILEQGRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHSPEMGARPLRRVIEQYLEDPL
AELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPATIPTGES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB2 YP_515569.1 ATP-dependent Clp endopeptidase ATP-binding chain B VFG0079 Protein 0.0 51
clpB2 YP_515569.1 ATP-dependent Clp endopeptidase ATP-binding chain B VFG0080 Protein 1e-145 49