Gene Information

Name : kdtA2 (CF0408)
Accession : YP_515325.1
Strain : Chlamydophila felis Fe/C-56
Genome accession: NC_007899
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 484282 - 485046 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGGAAGAACAAGTATTTGCTAGTAAGAAAGTTGGAGTTTTACCAGCAAGATGGGGTAGCGTCAGATTCACTGGAAAGCC
CCTAGCAAACATCCTTGGAAAGTCTTTGATACAAAGAACTTACGAGAACATTAGTCAAAGCACAACGCTGGATAAGGTTG
TTGTAGCCACTGATAATCAACGCATTATGGACCATGTTTTAGACTTTGGCGGTGATTGCGTGATGACCAGCCCGGAGTGT
GCTAACGGCACAGAGCGGACAGCAGAAGCTATATCGCGTTACTTTCCAGAAGCCGAGATCATTGTAAATATTCAAGGGGA
TGAGCCCTGCTTACAACACACCGTTGTCGATACTCTTGTCCGCAAACTTGAAGAATCCCCAGAGATTCAAGTGGTTACTC
CAGCTGCCAAGACCACAGACTCTCATGAAATCTTAACTAATCAAAAAGTGAAATGTGTTTTCGATAAAAATGGAAAGGCT
TTATATTTTAGCAGAAGTCCTATTCCACACATCTTGAAGAAAGAGACTCCAATATATCTTCATATTGGTGTGTATGCGTT
TAGAAGGAATGCACTGTTTAGTTACATTGAATCTACCCCAACATCCTTAAGCCAAGCCGAAGATCTTGAGCAACTACGCA
TACTAGAACATGGTGGATCTATCCATATATGTGTAGTGGAAGCTAAAAGTCCTTCAGTTGATTATCCAGAAGACATAAAT
AAGGTGGAAAAATACTTAACATGTCATTCAAGTGCATCTTTTTAA

Protein sequence : 
MEEQVFASKKVGVLPARWGSVRFTGKPLANILGKSLIQRTYENISQSTTLDKVVVATDNQRIMDHVLDFGGDCVMTSPEC
ANGTERTAEAISRYFPEAEIIVNIQGDEPCLQHTVVDTLVRKLEESPEIQVVTPAAKTTDSHEILTNQKVKCVFDKNGKA
LYFSRSPIPHILKKETPIYLHIGVYAFRRNALFSYIESTPTSLSQAEDLEQLRILEHGGSIHICVVEAKSPSVDYPEDIN
KVEKYLTCHSSASF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-35 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-35 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-35 41