Gene Information

Name : clpB1 (CF0378)
Accession : YP_515295.1
Strain : Chlamydophila felis Fe/C-56
Genome accession: NC_007899
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp endopeptidase ATP-binding chain B
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 441427 - 444021 bp
Length : 2595 bp
Strand : +
Note : Hemolysin B, EC 3.4.21.92

DNA sequence :
ATGGATAAGATTTCGGATGCGGTAAGCGAAGCTCTAGAAAAAGCTTTTGAGCTCGCTAAATCAGCAAAAAATCCTTATGT
AAGTGAAAACCATTTTCTTAAATGTCTTTTAGAAAATACTGAGTCATTATTTTATTTGATAATAAAAGACATACAAAGCA
ACCCCAAATTACTTATTACTGCAGTGGACGAGGCCCTTTCTCTAGAGCCCTCTGTTGTCAGTGGAGATGCTATGCCTAAG
CCTTCTCCAGGGCTACAAAGTCTACTTTTAGATGCTAGGCAAACGGCTAAAGATCTCGGAGATGAGTACCTTTCTGGAGA
TCATGTACTCCTAGCTTTTTGGAAATCCAATAAGGAGCCTTTCGCTTCTTGGAAAAAAACGGTAAAAGTATCCTTAGATG
ATCTCAAGAAACTCATTATTAATATAAGGCGTGGAAATCGTATGGACTCTCCTAGCGCAGAAAATAATCTTCGGGGCCTA
GAAAAGTATTGTAAGAACTTAACCTCGTTAGCAAAAGATGGAAAATTAGATCCTGTGATTGGTAGGGACGAAGAAATTCG
TCGTACAGTTCAAGTTTTATCACGAAGAACTAAAAATAACCCCATGCTTATAGGTGAGCCTGGAGTTGGGAAAACAGCAA
TTGCTGAGGGGCTGGCCCTGCGTATTATTCAGGGGGATGTGCCAGAAAGCTTAAAAGGTAAACAGCTCTACGTTTTGGAT
ATGGGAGCATTAATTGCCGGAGCAAAATATCGCGGAGAATTCGAAGAGCGCTTAAAAAGTGTGCTTAAAGATGTAGAGTC
TGTGGATGGTGAGAGTATTTTATTCATTGATGAAGTGCATACTCTTGTAGGTGCTGGAGCTACTGATGGTGCTATGGATG
CTGCAAATTTATTAAAGCCCGCTTTAGCAAGAGGTACTCTGCATTGTATCGGAGCTACAACTCTTAATGAATACCAAAAA
TATATAGAAAAAGATGCCGCTTTAGAACGGCGTTTCCAGCCTATTTTTGTAACAGAACCTTCTTTAGAAGACGCCGTGTT
TATTCTTCGCGGTCTTCGTGAGAAGTATGAAATTTTCCATGGCGTGCGTATTACTGAGGGAGCATTAAATGCTGCCGTTC
TTCTTTCTTATAGATATATTCCCGATCGTTTTCTTCCAGATAAGGCGATTGACTTGATAGACGAGGCTGCAAGTTTAATT
CGCATGCAAATCGGAAGTTTGCCCCTGCCTATCGATGAGAAAGAGCGGGAACTCGCTGCTTTGATTGTTAAGCAAGAAGC
CATAAAACGTGAAAAAGCTCCTTCATATCAAGAAGAAGCGGAGGCTATGCAGCAGTCTATAGATCAGCTTAAGGAAGAGT
TGGCAGTTTTGCGTCTGCGTTGGGATGAGGAGAAAAAACTTATCTCAGGCCTTAAGGAGAAAAAGAATTCTTTAGAAAAT
ATGAAGTTTTCTGAAGAAGAAGCTGAACGCGTTGCTGATTACAATCGTGTAGCAGAGCTACGCTATAGTTTAATTCCTGC
TCTTGAAGAAGAAATTCGTCAAGATGAAGAAGCTTTAAATCAAAGAGACAATCGCCTTCTTCAAGAAGAAGTGGATGAGC
GTCTTATTGCTCAGGTAGTGGCAAATTGGACAGGAATTCCTGTTCAGAAAATGTTAGAAGGCGAAGCCGAGAAGCTTCTC
GTTTTAGAAGAGTCTTTAGAAGAGCGCGTTGTTGGTCAGCCATTTGCTATTGCAGCTGTTAGTGATTCTATACGTGCTGC
CCGTGTAGGACTTAGTGATCCTCAACGACCTTTAGGAGTTTTCTTATTTTTGGGGCCTACGGGAGTGGGGAAAACAGAAC
TTGCTAAAGCTCTCGCAGATCTTTTGTTTAATAAAGAAGAGGCGATGGTACGCTTTGACATGACCGAATATATGGAAAAA
CATTCCGTATCCAAATTGATAGGATCGCCTCCAGGTTATGTAGGTTACGAAGAAGGGGGAAGTCTTTCTGAAGCTTTACG
TCGACGTCCTTATTCCGTCGTGCTGTTTGATGAAATTGAAAAAGCAGATAAAGAAGTATTTAATATTCTCTTGCAAATCT
TTGATGAAGGCATTCTTACGGATAGTAAAAAGCGTAAGGTAAATTGTAAAAATGCCTTATTCATTATGACTTCAAATATA
GGTTCTCAAGAACTTGCCGATTACTGCGCTAAGAAGGGAAGAGAGGTAAGTAAGGAGACTGTATTATCGGTAGTTTCCCC
AGAATTAAAGAAATACTTCAGTCCAGAGTTTATCAATCGTATTGATGATATTCTTCCTTTTGTTCCTTTGAATACCGAAG
ATATTGTAAAAATTGTCGGTATTCAGATGCGTAGAGTGGCTCAACGCTTGTTAGAAAGACGTGTAACATTAACTTGGGAT
GATTCTGTGATACTCTATTTAAGTGAGCACGGTTATGACAGTTCCTTTGGAGCACGGCCCTTAAAACGGTTAATTCAACA
GAAGGTAGTCACCTTGTTATCAAAAGCTTTGCTTAAAGGCGATATTAAATCAGATACGTCTATAGAGCTTACAATGTCTC
GGGATGTCTTGCTTTTCAAAAAAGTTAGCGGTTAG

Protein sequence :
MDKISDAVSEALEKAFELAKSAKNPYVSENHFLKCLLENTESLFYLIIKDIQSNPKLLITAVDEALSLEPSVVSGDAMPK
PSPGLQSLLLDARQTAKDLGDEYLSGDHVLLAFWKSNKEPFASWKKTVKVSLDDLKKLIINIRRGNRMDSPSAENNLRGL
EKYCKNLTSLAKDGKLDPVIGRDEEIRRTVQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRIIQGDVPESLKGKQLYVLD
MGALIAGAKYRGEFEERLKSVLKDVESVDGESILFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNEYQK
YIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVLLSYRYIPDRFLPDKAIDLIDEAASLI
RMQIGSLPLPIDEKERELAALIVKQEAIKREKAPSYQEEAEAMQQSIDQLKEELAVLRLRWDEEKKLISGLKEKKNSLEN
MKFSEEEAERVADYNRVAELRYSLIPALEEEIRQDEEALNQRDNRLLQEEVDERLIAQVVANWTGIPVQKMLEGEAEKLL
VLEESLEERVVGQPFAIAAVSDSIRAARVGLSDPQRPLGVFLFLGPTGVGKTELAKALADLLFNKEEAMVRFDMTEYMEK
HSVSKLIGSPPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVFNILLQIFDEGILTDSKKRKVNCKNALFIMTSNI
GSQELADYCAKKGREVSKETVLSVVSPELKKYFSPEFINRIDDILPFVPLNTEDIVKIVGIQMRRVAQRLLERRVTLTWD
DSVILYLSEHGYDSSFGARPLKRLIQQKVVTLLSKALLKGDIKSDTSIELTMSRDVLLFKKVSG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-101 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_515295.1 ATP-dependent Clp endopeptidase ATP-binding chain B VFG2084 Protein 1e-100 41
clpB1 YP_515295.1 ATP-dependent Clp endopeptidase ATP-binding chain B VFG2076 Protein 8e-115 41