Gene Information

Name : pyk (CF0336)
Accession : YP_515253.1
Strain : Chlamydophila felis Fe/C-56
Genome accession: NC_007899
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 394233 - 395678 bp
Length : 1446 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCAAGAACGAAAATCATTTGTACTATAGGTCCAGCAACAAATACCCCAGAAATGCTAGAGAAGCTCTTAGACGC
AGGAATGAATGTTGCTAGGTTAAATTTTAGCCATGGTACTCATGAAAGTCATGGTCAGACAATCCGTCTCCTTAAAGAAT
TGCGAGAAAGTAAGGGTGCTCCTTTAGCCATCATGTTAGATACTAAGGGACCCGAAGTTCGCTTGGGAAAGGTTCCTACA
CCAATCAAGGTATCTCGGGGTCAGAAAATCACCTTAGTAGGGAAAGATATCGAAGGGTCTATGGAAGAGGGAATTACTTT
ACATCCTCGGTGTGTGTTTCCTTTTGTGCGTGAAGGTGCAGAAGTCCTGATAGATGATGGATATATTCAAGCGATTGTGG
TTTCTACCGGTGATGATCATCTGGAATTAGAATTTATTAATTCCGGAGAGTTAAAATCCAATAAGTCTTTGAGTATCAGA
GAAATAGATCTTGCATTGCCATTCATGACGGATAAGGATATCGCTGATCTTAAGTTCGGGGTTGAACAAGGTGTTGATGT
TATTGCAGCTTCTTTCGTTCGCTGTGCAGAAGATATAGAAAGCATGCGTAAATGCCTAGCAGATTTTGGACGTGCAGATA
TGCCAATTATTGCTAAGATAGAAAATCGGTTGGGCGTGGAAAATTTCTCTAAGATTGCCCAGGCTTCAGACGGGATTATG
ATTGCCCGAGGGGATTTAGGAATTGAGCTTTCTGTTGTAGAAGTCCCCACTTTACAAAAGTTCATGGCAAGAGTGTCTCG
TGAAACTGGACGTTTTTGTATTACCGCTACGCAAATGTTAGAATCTATGATTCGCAATGTATTGCCAACTCGTGCTGAAG
TTTCGGATATTGCTAATGCTATTTATGACGGTACGTCTGCAGTAATGTTATCGGGAGAAACAGCTTCAGGAAGTTATCCT
ATAGCAGCCGTTAAAATTATGCGATCTGTGATTCAGGAGACAGAAAAAAATCTCAATTATAGCTCTTTCCTTAATCTTAA
TGATAGTGAATGTGCTGTTAAGGTATCTCCTTATCTTCAATCTATAGGCTTATCAGGAATTCAAATTGCAGAAAAAGCAG
AGGCTAGAGCTATTATTGTTTATACGGAATCTGGAGGATCTCCGATTTTTCTTTCCAAATACCGTCCTCGCTTCCCAATC
ATTGCTGTTACACCTAATCGAGATGTGTACTATAGGCTTGCCTTAGAGTGGGGTGTGTACCCTATGCTTACAGAGGAATC
CGTCCGTGCTGTATGGCGGCATCAAGCTTGTGTTTATGGTATCGAAAGGGGAATTTTATCAAATTACGATAAAGTTTTAG
TCCTGAGTCGTGGTGCGCAAATGAAAGATACAAATAATCTGACTTTGACAACAGTAAATGACATCATTACAGCATCAGCT
AAATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGQTIRLLKELRESKGAPLAIMLDTKGPEVRLGKVPT
PIKVSRGQKITLVGKDIEGSMEEGITLHPRCVFPFVREGAEVLIDDGYIQAIVVSTGDDHLELEFINSGELKSNKSLSIR
EIDLALPFMTDKDIADLKFGVEQGVDVIAASFVRCAEDIESMRKCLADFGRADMPIIAKIENRLGVENFSKIAQASDGIM
IARGDLGIELSVVEVPTLQKFMARVSRETGRFCITATQMLESMIRNVLPTRAEVSDIANAIYDGTSAVMLSGETASGSYP
IAAVKIMRSVIQETEKNLNYSSFLNLNDSECAVKVSPYLQSIGLSGIQIAEKAEARAIIVYTESGGSPIFLSKYRPRFPI
IAVTPNRDVYYRLALEWGVYPMLTEESVRAVWRHQACVYGIERGILSNYDKVLVLSRGAQMKDTNNLTLTTVNDIITASA
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-62 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-61 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_515253.1 pyruvate kinase VFG0479 Protein 9e-63 42