Gene Information

Name : FTL_0476 (FTL_0476)
Accession : YP_513248.1
Strain : Francisella tularensis LVS
Genome accession: NC_007880
Putative virulence/resistance : Virulence
Product : lysine decarboxylase, inducable
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 452890 - 455031 bp
Length : 2142 bp
Strand : +
Note : -

DNA sequence :
ATGAAAACTGTTGTATTTGTCTATAAAGATACCTTAAAGTCATATAAGGAAAAATTTTTACTAAAAATTGAGAAAGATCT
TAAAAATCATCATGAGTATTATACTTTGAAGCTTGATGATTTATCCGAAGTGGTTGAAATTCTTGAGGAGAACTCTAGAA
TATGCTGTATTGTTTTAGATAGAGCTAGTTTCAATATTGAAGCTTTTCATAATATTGCGCACCTTAATACAAAGCTGCCA
ATATTTGTAGCATCTGACTATAGTCAAAGTATTAAGCTTAATCTGCGTGATTTTAATCTAAATATCAACTTCTTGCAGTA
TGATGCTTTAGCTGGTGAGGATTCTGACTTTATTCACAAAACTATCACAAATTATTTTAATTATATATTGCCACCGTTGA
CTTATGAGTTATTTAAGTACTCTAAATCTTTTAATTCGGCTTTTTGTACTCCAGGTCACCAAGGAGGTTATGGTTTTCAG
CGTTCTGCAGTAGGGGCTTTGTTTTATGATTTTTATGGCGAGAATATTTTTAAGACAGATTTATCTATTTCAATGAAAGA
GCTGGGAAGCTTGCTTGATCATTCTGAAGCACATAAGGACGCTGAAGAATATATATCTAAAGTTTTTAAATCAGACAGAT
CACTTATTGTTACAAATGGTACTTCAACAGCTAATAAAATAGTGGGAATGTATAGTGTTGTTGATGGTGATACGATTCTT
GTAGATAGAAATTGCCATAAATCAGTGACACATCTAATGATGATGGTTGATGTTAACCCAATATATCTAAAACCAACCAG
AAATGCTTATGGAATAATTGGTGGGATTCCTAAAAAAGAGTTCAAAAGAGAAACTATCCAAGAAAAGATAGATAATAGTA
ATATTGCTGATAAGTGGCCTGAATATGCGGTAGTTACAAACTCAACTTATGACGGTATCCTTTATAATACTGATACGATA
CATCGAGAGCTTGATGTTAAAAAACTACATTTTGATAGTGCTTGGATACCATATGCAATATTTCATCCAATTTATAAGCA
TAAATCAGCAATGCAAATTGAGCCAAGACCAGAACATATAATTTTTGAAACACAGTCAACACATAAACTTTTAGCGGCCT
TTAGCCAATCATCAATGCTGCATATAAAAGGCGACTATAATGAAGAAGTATTAAATGAAGCGTTTATGCTGCATACTTCA
ACATCACCTTTTTATCCGATAGTTGCTAGCGTGGAAACAGCAGCAGCAATGATGGAGGGCGAGCAAGGCTATAATCTTAT
CGACAAGACTATTAACTTAGCTATAGATTTTAGAAGAGAACTAATCAAACTAAGATCTGAAGCAAATGGTTGGTTTTTTG
ATGTTTGGCAACCTGATAATATCTCTAATAAAGAGGCATGGCTTCTGAGAAATGCTGATAAATGGCATGGATTTAAAAAT
GTTGATGGTGATTTTCTCTCATTAGACCCTATCAAAATAACAATTCTAACTCCTGGGATAAAAGATAATGATGTTCAAGA
TTGGGGAGTACCAGCTGATGTGGTCGCTAAATTCTTAGATGAGCATGATATTGTGGTTGAGAAGTCTGGACCATATTCAT
TACTATTTATATTTAGTTTAGGTACAACAAAAGCTAAATCAGTAAGGCTAATTTCGGTATTGAATAAATTCAAACAAATG
TATGATGAAAATACACTTGTTGAAAAAATGCTACCAACTTTATATGCGGAAGATCCTAAATTTTATGAAGATATGAGAAT
TCAAGAAGTTAGTGAAAGATTACATCAGTATATGAAAGAGGCTAATCTTCCTAATCTCATGTATCATGCTTTTAATGTGC
TACCAGAGCAACAGCTAAATCCTCATAGGGCTTTTCAGAAATTATTAAAAGGTAAGGTTAAAAAGGTTCCTCTAGTAGAA
CTGTATGAGCATACTTCAGCTGTTATGATATTACCTTATCCACCTGGGATACCTGTTATTTTTCCTGGAGAGAAGATAAC
CGAAGAATCTAAAGTAATATTGGATTTCTTATTAATGCTTGAGAAAATAGGTTCGATGTTGCCTGGCTTTGATACAGATA
TTCATGGTCCTGAGAGGGCAAAAGATGGTAAGCTCTATATCAAAGTTATTGATGATAAATAA

Protein sequence :
MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLP
IFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQ
RSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL
VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTI
HRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTS
TSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN
VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQM
YDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVE
LYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 55
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 1e-167 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FTL_0476 YP_513248.1 lysine decarboxylase, inducable VFG1670 Protein 6e-168 50