Gene Information

Name : FTL_0294 (FTL_0294)
Accession : YP_513086.1
Strain : Francisella tularensis LVS
Genome accession: NC_007880
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 278860 - 281394 bp
Length : 2535 bp
Strand : -
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGCAAGATATTTCTAATCACACCCCGATGATACAACAATATTTGAAAATTAAATCACAGTATCAAGATATATTATTATT
TTACCGTATGGGCGATTTTTATGAGCTTTTTTTTGATGATGCTAAAAAAGCTGCTGAGCTCTTAGATATTACGCTCACAG
CTCGTGGTAAATCAAATGGTGAATCAATCCCGATGGCTGGAGTGCCATATCATGCCGCTGAAGCCTATATTGCAAAAATT
GTCAAAAAAGGTCTATCGATTGCTATCTGTGAGCAAACTGGCGATCCAAACACCTCAAAAGGTCCCGTTGAGAGACAAGT
GACACGTATTATAACTCCAGCGACAGTTTCTGAAGAAGCTTTTTTAGACAACAATCAAGATAGTATTCTTGTGAGTATTT
TTGAAAAAAATAATAAGTATTATTTAGCATACACAAGCTATACGCAAGGAAAAATTTATCTAGTTAAAACACTAACTAGC
CTAAATGAGCTAAAAAATACTGTTCTGAAATTATCACCTCAAGAAATTATTACTAACTCTCGAGAACTTGCTCAGCAGAA
TCCTTTTAAAAAACCAATTAAAGCTTTAGAAGAATGGTATTATAGTAATTTTGAGGCAAAAAAATATATCAATGATTCTC
TTGATACCAATATTGCTAATAATATCCTAAATCTTTATAAAAATGATCAACTAACAACTATTGGCTCAATACTTAGCTAC
CTTACAAATATTCTCAAGGATACTCCTAGGCATATTACTGATATCAGCTATGAACAAGAACAAGATACGCTTAACATTGA
TATAAATAGTCGTATAAATCTTGAGCTAGATAATAACTCAAAAAGTAGCTTACTTAGCATAATTGGTAAATGTAAGACTA
GCCTTGGTAGTCGTTTACTAAAAAGGTATTTTAGCAATCCAACAAGAAATTTAAACATTTTAGCTACTCGCCATAGTATT
ATAAACAGTTTAGGTGAAAATCAACATTTTTTAAAAATTCAAGATGTGCTTAGTTATATCAGTGATATTGAAAGGATAAT
CTCACGAGTAGCACTTGGAACTGTAAAACCTAAAGATCTTGTCGCTCTGCGTTACTCCCTTGAGCAGCTACCAATACTCA
AAAAACTCCTCAGTGAAAAAAATACTCCAGAGATTACAAATATAAATAACCGCATCCACCAGCTTGATGAGCTTGTTACA
CTTTTAGATAAAGCGATTATTGAGAATCCCCCAACAACCATTCGTGATGGTGGCGTCATCAAAGAAGGTTTTGATAAAGA
ACTAGATGAGCTAAAAAGCATAAAAGATAATTCTTATGATTTTCTAATCAAGTTTGAAGAATTACAAAAACAGAAAATTG
GTATAAGTACACTCAAAGTTGGTTACAATCGTGTTCATGGCTATTATATTGAGTTATCTAAACAGCATGCTGATAAAATC
CCAACTGAGTATGTCAGACGCCAAACCTTAAAAGCTAGTGAACGCTATATCACCGAAGAACTAAAAAACTTCGAAGATAA
AGTCCTTTCATCAAAAGAAAAGGCTCTAGCCCGTGAAAAGTTAATCTATGATACTCTATTAAAGAAAGTTATCGAATACT
ACAAACAAATTCAAGAAACTGCTGCAAGTATTGCTGAAATAGATGTTTTAGCAAATTTTGCTGAGAGAGCTATTAAGCTT
AAACTTAGTCAACCTAAGTTTAATAACTTAGCAAAATTAGAACTTAAAGAAGTTCGTCACCTTGCTATTGAGCATAATAT
TGATGAACCATTTATCCCAAACGATACTTTACTAAGCAAAGATACTAATACCCTACAAATAATAACTGGTCCAAATATGG
GCGGTAAATCGACATATATGCGCCAAGTTGCACAGCTAATATTTCTAGCTTATATCGGCTCATTTGTACCAGCAAGTTAT
GCAGATATTTGTGATATTGATACTATCTACACAAGGATTGGTGCATCTGATGATATTTCTAGCGGTAGATCAACTTTTAT
GGTTGAAATGACTGAAACAGCCTATATTCTCAATAATGCTAGTGCCAAATCACTAGTAATAATGGATGAAATAGGTCGTG
GCACAAGTACTTTTGATGGTTTAGCATTAGCTAAAGCATGTGCAGAGAAGTTTGCACAAATGGGGGCTTTTACTTTATTT
GCAACACATTATTTTGAGCTAACAGAATTGGCTAAACAATATCCAAATGTATGTAACATCCATTTTGAAGCAAAAGAATA
TAAAGATAATATCTACTTTATGCACAAAGCTGTTACAGGAGCGGCTAAAAAATCCTATGGCATCCAAGTAGCCAAACTTG
CCGGAATATCTCAAGATGTCCTAGAGTCAGCAAAGCAAAATTTATATAATCTCGAAAAAAAGCAACAGCTAACAGAATCA
ACCCAAGTCCAAGCTCAATTTCAGTTAGAACCAACAACTCAAAATCCTTTACAACAAAAACTTGATGCTATCGATATTAA
TACAATAACACCTCTAGAAGCACTAAATATTCTCTTTGAACTAAAAAAACGCTAA

Protein sequence :
MQDISNHTPMIQQYLKIKSQYQDILLFYRMGDFYELFFDDAKKAAELLDITLTARGKSNGESIPMAGVPYHAAEAYIAKI
VKKGLSIAICEQTGDPNTSKGPVERQVTRIITPATVSEEAFLDNNQDSILVSIFEKNNKYYLAYTSYTQGKIYLVKTLTS
LNELKNTVLKLSPQEIITNSRELAQQNPFKKPIKALEEWYYSNFEAKKYINDSLDTNIANNILNLYKNDQLTTIGSILSY
LTNILKDTPRHITDISYEQEQDTLNIDINSRINLELDNNSKSSLLSIIGKCKTSLGSRLLKRYFSNPTRNLNILATRHSI
INSLGENQHFLKIQDVLSYISDIERIISRVALGTVKPKDLVALRYSLEQLPILKKLLSEKNTPEITNINNRIHQLDELVT
LLDKAIIENPPTTIRDGGVIKEGFDKELDELKSIKDNSYDFLIKFEELQKQKIGISTLKVGYNRVHGYYIELSKQHADKI
PTEYVRRQTLKASERYITEELKNFEDKVLSSKEKALAREKLIYDTLLKKVIEYYKQIQETAASIAEIDVLANFAERAIKL
KLSQPKFNNLAKLELKEVRHLAIEHNIDEPFIPNDTLLSKDTNTLQIITGPNMGGKSTYMRQVAQLIFLAYIGSFVPASY
ADICDIDTIYTRIGASDDISSGRSTFMVEMTETAYILNNASAKSLVIMDEIGRGTSTFDGLALAKACAEKFAQMGAFTLF
ATHYFELTELAKQYPNVCNIHFEAKEYKDNIYFMHKAVTGAAKKSYGIQVAKLAGISQDVLESAKQNLYNLEKKQQLTES
TQVQAQFQLEPTTQNPLQQKLDAIDINTITPLEALNILFELKKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 1e-159 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FTL_0294 YP_513086.1 DNA mismatch repair protein MutS VFG0562 Protein 5e-180 45