Gene Information

Name : guaA (Jann_2221)
Accession : YP_510163.1
Strain : Jannaschia sp. CCS1
Genome accession: NC_007802
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2226150 - 2227757 bp
Length : 1608 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACACTGCCGCCGTCCCAACTGCCGATGAACTTGGCCCCGCCCATCACGAACGCCTGTTGATCATCGACTTCGGGTC
GCAGGTCACGCAACTAATTGCCCGCCGCCTGCGCGAATTGAACGTCTATTGCGAAATCCACCCCTACCAGAACGTCGATG
ACGCCTTTATCGGGGACTTTGCCCCCAAGGCGATCATCTTCTCGGGCGGGCCGGATTCGGTCACACGGGATGGCTCTCCC
CGCCCTCCACAGGCGGCCTATGCGGCGGGCGTGCCGATCCTGGGGATCTGCTATGGGCAGCAAGTCATGATGCAGGACCT
CGGCGGAGAGGTGCATGGCGGCAAGATCTCGGGCGGCGGAGGCACGGCAGAGTTCGGACGGGCCTTTGTGGAACCCACGG
GCGCATTGGCGTTGTTGCAGGGCTGGTTTGCGGATGGCAAGGAACAGGTCTGGATGAGCCACGGCGACCACGTCGCGAAA
CTGGCGCCCGGATTTGAGGTCTACGGCACCTCCCCCAACGCGCCCTATGCGATCACGGCGGATCTTGAGCGGAATTTCTT
CGCCGTCCAGTTCCATCCCGAGGTCCATCACACCCCGCGCGGCGCCATGCTGTATGAGAATTTTGTGAAACTAGCGGGTT
TCTCCGGCGACTGGACCATGGGTGCCTACCGCGAACAGGCGGTGGAGGCGATCCGTGCGCAGGTGGGCGATGCAAAGGTC
ATCTGCGCGCTGTCGGGCGGGGTCGATTCGTCGGTGACCGCAGCGCTTCTACACGAGGCCATCGGCGATCAGCTGACCTG
CGTCTTCGTGGATCACGGCTTGTTGCGCCTGAATGAGGGGGCAGAGGTCGTGGAGATGTTCCGCGATCACATGAACCTCC
ACGTGATCCATGCCGAGGAGCAGGACCTGTTTCTGGGCGAGCTGGACGGCGTGTCCGACCCGGAAACCAAGCGCAAGATT
ATCGGACGCTTGTTCATCGATGTGTTCCAGAAATATGCGGGCCAGATCGAGGGCGCGGATTTCCTCGCCCAGGGCACGCT
TTACCCGGATGTCATTGAAAGCGTGAGCTTTTCCGGCGGTCCCAGCGTAACGATCAAGTCGCACCATAACGTCGGTGGCC
TGCCCGAGAAGATGGGTTTGACGCTGGTGGAACCCCTGCGCGAATTGTTCAAGGATGAGGTCCGCGCCCTGGGTCGTGAG
TTGGGCCTGCCCGCCCATTTCATCGCCCGCCACCCCTTTCCCGGCCCCGGCCTCGCCATCCGTTGCCCGGGTGAGATCAC
GCGCGCGAAACTGGATATCCTGCGCCAGGCCGACGCGGTCTACATCGACCAGATCCGCCGCCACGGCCTTTATGATGAGA
TCTGGCAGGCCTTCGTCGCGATTCTGCCGGTGCGCACCGTCGGTGTTATGGGCGATGGCCGCACCTATGATTACGCCTGT
GCCCTGCGCGCCGTGACCTCCGTCGATGGGATGACGGCCGACTACTACCCGTTCAGCCACGATTTTCTGGGTGAAACGGC
GACCCGCATTATTAATGAGGTGCCCGGTATCAACCGCGTGACCTATGACATCACCTCCAAACCGCCGGGCACCATTGAGT
GGGAGTGA

Protein sequence :
MNTAAVPTADELGPAHHERLLIIDFGSQVTQLIARRLRELNVYCEIHPYQNVDDAFIGDFAPKAIIFSGGPDSVTRDGSP
RPPQAAYAAGVPILGICYGQQVMMQDLGGEVHGGKISGGGGTAEFGRAFVEPTGALALLQGWFADGKEQVWMSHGDHVAK
LAPGFEVYGTSPNAPYAITADLERNFFAVQFHPEVHHTPRGAMLYENFVKLAGFSGDWTMGAYREQAVEAIRAQVGDAKV
ICALSGGVDSSVTAALLHEAIGDQLTCVFVDHGLLRLNEGAEVVEMFRDHMNLHVIHAEEQDLFLGELDGVSDPETKRKI
IGRLFIDVFQKYAGQIEGADFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPEKMGLTLVEPLRELFKDEVRALGRE
LGLPAHFIARHPFPGPGLAIRCPGEITRAKLDILRQADAVYIDQIRRHGLYDEIWQAFVAILPVRTVGVMGDGRTYDYAC
ALRAVTSVDGMTADYYPFSHDFLGETATRIINEVPGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-122 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-122 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-122 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-107 47