Gene Information

Name : thiC (ECH_0798)
Accession : YP_507596.1
Strain : Ehrlichia chaffeensis Arkansas
Genome accession: NC_007799
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 813891 - 815555 bp
Length : 1665 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAAATAGACTTTAATACCCTCTTTCCTTCTTCAACTAAAGAATACATATCAGGCACAATATACAACAATATAAAAGT
TGGAATGCGTAGAATTCATATTAATGATAACAGTGAATCCATTCTAACATATGATACTGGAGGACCACATACTGATCAAA
AAATCAAAATTGACATTAATCAGGGTATTGAAAAGATAAGGCTTAATTGGATTGTAGATAGACAAGACGTAGAGTATCAT
AAAAGACAAGAAGTAAACACAAATTCTGAATACGCATTTCCACTACAAAGTAATAATATCTTAAAAGCAAATAGTAATAA
ACCTATAACCCAGATGTATTATGCTCGAAACAATATTATTACTCCAGAAATGGAATATGTAGCAATACGAGAAAACGCAC
TAAGACAAAAGATTCTTTCTTATAAACCAACTGTCATGGCACCAGAAATTACTCCAGAATTCGTACGACAAGAAATAGCA
TCTGGGAGAGCAATCATTCCAGCAAATGTAAATCATCCTGAATCAGAACCAATGATAATAGGCAAGAATTTCTTAGTAAA
AATCAATGCTAATATTGGTAATTCAGTAGTTAGTTCAAGCATTGAAGACGAACTTCAAAAAATGATATACGCAATTATAT
ACGGTGCTGATACAGTTATGGATTTATCTACAGGGAACAATATACATAATATTAGAGAATGGATTATCAGAAACAGCCCA
GTACCAATAGGTACAGTACCTATATATCAAGCATTAAACAAAGTAAATGGAGTAGTAGGAGACCTAGATTTCAATATCTT
CAAAAAAACATTAATAGAACAAGCAGAACAAGGTGTTGACTATTTTACCATACATGCAGGAGTATTAAAAAATTACATTG
ACTACACAGATAACAGGCTAACTGGCATCGTATCAAGAGGTGGAGCTATTATGGCACACTGGTGTACTATACATAATAAA
GAGAACTTTCTTTATACAAATTTTGAAGAAATATGCGATATTATGAAACACTATGACATTACTTTCTCTCTAGGAGATGG
ATTAAGGCCAGGATCCATAGCAGATGCAAACGATACAGCACAATTTTTAGAACTCAAAACACTAGGAGAACTTACAGACA
TTGCATGGAAGCACGATTGCCAAGTTATGATAGAAGGACCAGGCCATGTTCCTATGCATTTAATAAAAGAAAATGTAGAA
AAACAGGTTCACTTCTGTAAGGAAGCTCCATTCTATACTTTAGGACCATTAACTACAGACATTGCTCCAGGTTACGACCA
CATAACGAGTGCAATCGGCGCAGCAATTATAGGATGGTATGGCACTTCTATGTTGTGTTATGTTACACCGAAAGAACACT
TAGGATTACCTAACATTCAAGACGTAAAAGATGGAGTCATTGCATATAAAATAGCAGCACATGCAGCAGACTTAGCAAAA
GGTAATCCATCTGCTTATATACGTGATTATGCATTAAGTTATGCAAGGTTCAATTTCAAATGGTATGATCAATTTAACTT
ATCTCTTGATCCAGAAACGGCAAAATCACTACACGATGAATCTCTTCCTTCTGAGAATGCAAAGTCTGCTCACTTCTGTT
CAATGTGTGGGCCAAAATTCTGCTCAATGAAATTAACTCATCAAATAAAATCTATTGAAGAGTAA

Protein sequence :
MKIDFNTLFPSSTKEYISGTIYNNIKVGMRRIHINDNSESILTYDTGGPHTDQKIKIDINQGIEKIRLNWIVDRQDVEYH
KRQEVNTNSEYAFPLQSNNILKANSNKPITQMYYARNNIITPEMEYVAIRENALRQKILSYKPTVMAPEITPEFVRQEIA
SGRAIIPANVNHPESEPMIIGKNFLVKINANIGNSVVSSSIEDELQKMIYAIIYGADTVMDLSTGNNIHNIREWIIRNSP
VPIGTVPIYQALNKVNGVVGDLDFNIFKKTLIEQAEQGVDYFTIHAGVLKNYIDYTDNRLTGIVSRGGAIMAHWCTIHNK
ENFLYTNFEEICDIMKHYDITFSLGDGLRPGSIADANDTAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVE
KQVHFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAIIGWYGTSMLCYVTPKEHLGLPNIQDVKDGVIAYKIAAHAADLAK
GNPSAYIRDYALSYARFNFKWYDQFNLSLDPETAKSLHDESLPSENAKSAHFCSMCGPKFCSMKLTHQIKSIEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-179 64
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-179 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 9e-166 60