Gene Information

Name : serS-1 (ECH_0584)
Accession : YP_507395.2
Strain : Ehrlichia chaffeensis Arkansas
Genome accession: NC_007799
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 592179 - 593450 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGATATAGATTTTATAAAACAGAATCCAGAATTATTTGATAATGCAATGCAAGTACGAAATTCTGAAAAAGTTGC
AAAAAAAATTATAGAATTAGATGTTAAGAAAAGACATTTATTAACACAACTATACTCTTTACAGAAAGAACGTAATCAAA
TCACTCAAGAGATTGAAAAGTTAAAAAAAAATAATCTTCAGTGCAACATACAAATAGAATTATCAAAAAATGTAACAAGT
AAAATAAACGATATTAACAATATGATAAAAGAAGATTCTCAATTAGTTAATCTTCTCAATATGTTACCGAATATACCAGA
TGAAAGAGTACCTATTGGGAAAGACGAAAACAGTAATGTTGAATTGAGAAGACATGGGAATAAAACAAGCTTTGATTTTC
CAATAAAGACTCATTATGAATTAGGGGAAAATCTAAATTTAATGGATTTCAAACAAGCCGCAAAACTTTCTGGATCAAGA
TTTGTAATACTCAAAAATCAGCTTGCACAATTAGATCGTGCTTTATCTAATTTTATGCTAGATATTCATACTAAAGAATT
TGGTTATTCAGAAATATCTCATCCAATATTAGTTCATGAATCTGCTATGTATGGAGTAGGACAATTACCAAAATTTGCAG
ATGATTCCTTTAAAACAACAGAAAATTTTAGACTTATACCAACAAGTGAAGTAGCACTTACCAATTTGGTATCAAATATG
AATATTAATGGATGTGATTTACCTCTAAGATTTACTGCTTGTTCTCCATGTTTTAGATCAGAAGCAGGAAGTGCTGGTAG
AGATACAAGAGGCATGATGAGACAACATCAATTTAATAAAGTAGAATTAGTTAGCATTGTAACTGAAGAACAATCAGCAC
CAGAATTAGAAAGAATGACACAAATTGCTGAAGAAATTCTCAAGAGATTAGAATTACCATATAGAGTAATGATGTTGTGT
ACTGGAGATATGGGTTTTTCAGCAAGTATAACATACGATATTGAAGTATGGATACCAAGTCAGAATCAATACAGAGAAAT
TTCTAGTTGTTCAAATTGTAAAGCTTTTCAAGCACGTAGAATGAATACTAAATATACTACTATAATTAATAATGTTAAAG
TAAGTAAATTTGTACATACATTAAACGGTTCTGCTTTAGCAATAGGAAGAACTATTATTGCAATTTTAGAAAACTACCAA
AATAGAGATGGTTCTATAACAATACCGCATATTTTAAGAAAATATATGGATAATCAAGAAGTTATCAAATAA

Protein sequence :
MHDIDFIKQNPELFDNAMQVRNSEKVAKKIIELDVKKRHLLTQLYSLQKERNQITQEIEKLKKNNLQCNIQIELSKNVTS
KINDINNMIKEDSQLVNLLNMLPNIPDERVPIGKDENSNVELRRHGNKTSFDFPIKTHYELGENLNLMDFKQAAKLSGSR
FVILKNQLAQLDRALSNFMLDIHTKEFGYSEISHPILVHESAMYGVGQLPKFADDSFKTTENFRLIPTSEVALTNLVSNM
NINGCDLPLRFTACSPCFRSEAGSAGRDTRGMMRQHQFNKVELVSIVTEEQSAPELERMTQIAEEILKRLELPYRVMMLC
TGDMGFSASITYDIEVWIPSQNQYREISSCSNCKAFQARRMNTKYTTIINNVKVSKFVHTLNGSALAIGRTIIAILENYQ
NRDGSITIPHILRKYMDNQEVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-98 52