Gene Information

Name : smpB (ECH_0135)
Accession : YP_506963.1
Strain : Ehrlichia chaffeensis Arkansas
Genome accession: NC_007799
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 123530 - 123979 bp
Length : 450 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGGATATCGTAGTTGAGAATCGTAAAGTAAGGTTTAATTATTTTATTATTCAGGAATTTGATGCTGGTATTGTATTAAT
TGGTAGTGAAGTCAAGTCTTTACGCCAGAGAAAAGTCAGCATAGCTGAGGCATATGTTACTGAGCGGAATATGGAATTGT
GGCTATGTAATTTACATATTTCAGAATATAATCAGGCAAGTACTAGAAATCATAATCCTACCAGACCTAGGAAGTTACTA
TTGCGGAAAAAGCAAATATATAAAATATCTGGAAATATAAAGAATGATGGCTTTACTGTTGTACCATTGTGTTTATATTT
TAATGATAAGGGGATAGCAAAAGTTAAGGTTGTTATTGTAAAAGGTAAAAAGTTGCATGATAAGAGAGAGACAATAAAAA
CTAGAGATTGGAATAGAGAAAAAAGTCGTATACTACGTGGCGGAAACTAA

Protein sequence :
MDIVVENRKVRFNYFIIQEFDAGIVLIGSEVKSLRQRKVSIAEAYVTERNMELWLCNLHISEYNQASTRNHNPTRPRKLL
LRKKQIYKISGNIKNDGFTVVPLCLYFNDKGIAKVKVVIVKGKKLHDKRETIKTRDWNREKSRILRGGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 9e-21 44
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-19 41