Gene Information

Name : hemC (APH_0746)
Accession : YP_505325.1
Strain : Anaplasma phagocytophilum HZ
Genome accession: NC_007797
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 791293 - 792207 bp
Length : 915 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
TTGGGTATAGTTATGGTTATTAGAATAGGTACAAGAGGAAGCCTTCTAGCCATGCAGCAGGCTAGAATAGTGAAAACTGC
TATTGAAACCAATTATGCGGAGTTATCAACCCGTATAATTACCATAAAGACTTCTGGAGATATGAATACTCATGTACCTC
TTTATGATATTGGTGGTAAGGGGCTATTTATAAAGGAGATTGAGGAAGCTCTTTTGGATAATATAATAGATGTGGCTGTG
CATTCGGCTAAGGATGTTCCTGGCATATATTCCGAAGATCTAGATATTCCCTGTATTTTGCCCAGGGCATCAGCTTTAGA
TGCTTTTTTATCATCTAAATATGACAGTATAGCTTCTCTACCATTGAATGCAAAAATCGGTACTTCGTCGGTAAGGAGAA
AGGTGCAATTATTGACGATGAGGCCAGATTTAGAGATCATTCCCATGCGTGGCAATGTAGAAACAAGAATATCAAAAATG
CAGATGGGAGAGTGTGATGGTATTGTTTTGGCTGAAGCTGGTCTGTATAGGGTATCGAAAGATAATTTAATATCGGAAGT
ATTGCAGCCGGAAGTTATGTTGGGTGCAGTCGGTCAAGGAGCAATATGTGTTCAATGTCGCAGATATGATAGGAGGATAC
TTGAGATATTGAAGAAGTTAAACTGCCATAAGTCGTATACTACGGTATCAGCGGAGCGTAGCTTTATGAGGGCAGTAGAT
GGGTCTTGCAATACTCCCCTTGCTGCTATGGCGAAGTATATCGATATGGATATACTAACGATGAAGTGTATGTTAGCCGA
TGATGCCAGAAACATGGTATTTACAGAACGGGTTTTTGCAGAGCAAAATGCAGAAAGTGCAGGATATGAAATGGGGACAT
TGTTGAAAAATGAGTTACACCTTCACAGGTTATAA

Protein sequence : 
MGIVMVIRIGTRGSLLAMQQARIVKTAIETNYAELSTRIITIKTSGDMNTHVPLYDIGGKGLFIKEIEEALLDNIIDVAV
HSAKDVPGIYSEDLDIPCILPRASALDAFLSSKYDSIASLPLNAKIGTSSVRRKVQLLTMRPDLEIIPMRGNVETRISKM
QMGECDGIVLAEAGLYRVSKDNLISEVLQPEVMLGAVGQGAICVQCRRYDRRILEILKKLNCHKSYTTVSAERSFMRAVD
GSCNTPLAAMAKYIDMDILTMKCMLADDARNMVFTERVFAEQNAESAGYEMGTLLKNELHLHRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-44 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-44 43