Gene Information

Name : thiC (APH_0600)
Accession : YP_505190.1
Strain : Anaplasma phagocytophilum HZ
Genome accession: NC_007797
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 626150 - 627823 bp
Length : 1674 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGCACATGAATATTTCTGAAATTTACCCATCATCTAATAAAATATACATTAATTGCACTCTATATCCGGATGTTAAGGT
CGGAATGCGTCAAATAAATATTAGAAATTCTTCGCAGCGTTTCCTTCTCTACGATACTGCTGGTCCTTATACTGATTGCG
ATATTAAGGTTAATCTGACTGAAGGAATATCTAGCATAAGGCGAGATTGGATAGCTCGCAGGAATGATACCTATCCTATA
CGTAAGGCTAAGACTAATTCTGATGCTCGAGGTGTAAAGGCTCTTTCTGGAGATGATAGAGTAATATTGAAAGGAATAGC
TGGAGGTGCTCCAGTGACTCAACTCTTTTATGCTAAAAAAGGTATCATAACACCCGAGATGGAGTATGTAGCCGTGCGGG
AGAACGCTTTGCTTGAACAGGCTGAAGCTATCCCTGGTCTGTTATTGCCTACTAAGACACGTAAAATAACACCTGAGTTT
GTGCGTGAAGAGGTGGCTTGCGGAAGGGCTGTAATCCCATCAAATATCAATCATCCGGAATCTGAGCCTATGATTATAGG
TAGAAACTTCCTTGTGAAAATAAACGCTAATATAGGAAATTCTGCCGTACTTTCAAATATCGAAGATGAAGTGAAAAAGA
TGGTTTTAGCAGTTACGTATGGAGCTGATACAGTCATGGATCTGTCTACTGGTCATGATATTCACAACATACGAGAATTG
ATAGTGCGCAACAGCCCTGTGCCTATAGGTACTGTGCCTATATATCAAGCTCTAAACAAAGTTAATGGCATAGTTGGAGA
TTTAAGTTTTGAAGTATTCAAAGAAACGATAATAGAGCAGGCCGAGCAGGGGGTGGATTACTTCACCATACACGCGGGTG
TGTTGAAGAGCTACATTGAGCATACCCGTTCACGCACTACAGGAATTGTATCGCGTGGTGGTGCAATAATGGCACAGTGG
TGCTTGCTACACAACAAAGAGAACTTCTTGTACGAGAATTTTGAAGAGATTTGTGAAATAATGCGTAGTTACGATGTAAC
ATTCTCTTTGGGGGATGGTCTTAGACCTGGCTCAATTAATGACGCCAATGACGTAGCGCAGTTTTTAGAGCTTCGCACTT
TGGGAGAATTGGTAAAAATAGCACGTGCGCATGATTGTCAAGTTATAGTAGAAGGTCCTGGCCATGTGCCTATGCATTTG
ATTGAAGAAAATGTAAAAAAGCAACTTGATTTTTGTGATGAGGCGCCATTTTATACACTAGGCCCTCTGACTACGGATAT
AGCTCCTGGCTATGATCACATAACCAGTGCCATTGGTGCTGCTATGATAGGTTGGTATGGAACTGCGATGTTGTGCTACG
TAACACCTAAAGAGCATCTCGGATTACCCAATGCCGAAGACGTAAAAGCGGGTGTTATATCTTATAAAATCGCGGCTCAC
GCTGCTGACCTGGCGAAAGGTAATCCGGCCTCGTTTGCCCGTGATTATGCTCTCAGCCAAGCAAGATATGACTTTAGGTG
GGAGGACCAGTTTAACTTGTCTATAGATCCCGCAACTGCTAAAAAGCTGCACGATGAATCTTTACCTGGAAAGGGCGGAA
AAACAGCGCATTTTTGTTCCATGTGTGGGCCAAAATTTTGTTCCATGAAACTTAGCAAGGCTCTCAATGATTGA

Protein sequence :
MHMNISEIYPSSNKIYINCTLYPDVKVGMRQINIRNSSQRFLLYDTAGPYTDCDIKVNLTEGISSIRRDWIARRNDTYPI
RKAKTNSDARGVKALSGDDRVILKGIAGGAPVTQLFYAKKGIITPEMEYVAVRENALLEQAEAIPGLLLPTKTRKITPEF
VREEVACGRAVIPSNINHPESEPMIIGRNFLVKINANIGNSAVLSNIEDEVKKMVLAVTYGADTVMDLSTGHDIHNIREL
IVRNSPVPIGTVPIYQALNKVNGIVGDLSFEVFKETIIEQAEQGVDYFTIHAGVLKSYIEHTRSRTTGIVSRGGAIMAQW
CLLHNKENFLYENFEEICEIMRSYDVTFSLGDGLRPGSINDANDVAQFLELRTLGELVKIARAHDCQVIVEGPGHVPMHL
IEENVKKQLDFCDEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNAEDVKAGVISYKIAAH
AADLAKGNPASFARDYALSQARYDFRWEDQFNLSIDPATAKKLHDESLPGKGGKTAHFCSMCGPKFCSMKLSKALND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-174 62
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-174 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-161 58