Gene Information

Name : serS (APH_0427)
Accession : YP_505030.1
Strain : Anaplasma phagocytophilum HZ
Genome accession: NC_007797
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 441782 - 443068 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCATGATATCGAGTTTATAAAAAACAACCCTGAACTTTTTGATAAAGCAATGCTGTCTCGTGGGCTCGAGAGTCAAGC
TGCAAAGATCATAGAGCTTGATTTACAAAAACGTAAACTGCTAACAGAGCTTTATGCCCTAAGAGAGCAGCGCAATGCGA
TTACTAAAGAGGTAACTGTACTAAAGCAGAGCGGCGCAGATTGCTCGTCACATGTAGAAACTTCTAAGAAGCTTGCTCAT
GAAATTTCAGAGCTTGAAGAGCGTATTAAGCGTGACACCGGGCTCTCGTACCTGCTATGTAGTCTTCCAAATATTCCTGA
TGATGCAGTACCCTTTGGCAAAAGCGCTGATGATAACGTAGAAGTTCGTTCCTACGGACAGAAGAGGAGTTTTTCTTTTG
AAATTAAACCTCACTACGTTCTTGGTGAGATGCTCAACCTCATGGACTTCCGTAGAGCTGCTTTTCTATCAGGATCCAGA
TTTTCCATATTAAGTGGTCAGCTTGCAGCTTTGGAGAGGGGCCTTGCGTCTTTTATGTTGGAGATGCATACAAAGGAGTT
TGGATACACAGAAGTTTTTCATCCATCTCTAGTCAATGACCTTGCAATGTTCAATGTGGGGCAATTACCAAAATTTACCC
ATGACTCCTTTCAGACAACTGATGCCATGCGCTTGGTGCCGACTAGTGAGGTTGTTTTGACTAACTTAGTTGCAAATACA
AATCTGCATCGTAATTCTTTACCTCTCAGGTTTACCGCGTACTCACAATGCTTCCGTTCTGAAGCTGGTAGCGCTGGGCA
AGATACCAGGGGAATGATTCGTCAGCATCAATTTAGCAAGGTAGAGTTGGTAAGTATCACCGATGCTAGCCAGTCTAATG
TAGAACTGGAGCGTATGCTATCTGTGGCTGAAGAAGTGCTAAAAAGGCTCGAGTTACCATATCGAGTGGTGCTGCTATGT
ACGGGAGACATGGGATTTTCTGCTAGCATCTCTTACGATATTGAAGTATGGATGCCTGCTCAAAATAAATACAGAGAGAT
ATCAAGTTGCTCCAATTGTAAAGACTTTCAAGCAAGAAGAATGGGCGCAAAATGTTTCTACCTAGAAAAACAGAATAAGC
GTTCTTCTTTTGTGCATACCTTGAATGGTTCAGCCTTGGCGTTAGGAAGAACTATAGCTGCTATTATGGAGAATTATCAA
AATTCAGATGGGACTATAACAATACCTGATGCTCTGCGGAAGTTCATGTCAGCTGATTATATAAGGCCTGGAACTGCTCT
TCCCTAA

Protein sequence :
MHDIEFIKNNPELFDKAMLSRGLESQAAKIIELDLQKRKLLTELYALREQRNAITKEVTVLKQSGADCSSHVETSKKLAH
EISELEERIKRDTGLSYLLCSLPNIPDDAVPFGKSADDNVEVRSYGQKRSFSFEIKPHYVLGEMLNLMDFRRAAFLSGSR
FSILSGQLAALERGLASFMLEMHTKEFGYTEVFHPSLVNDLAMFNVGQLPKFTHDSFQTTDAMRLVPTSEVVLTNLVANT
NLHRNSLPLRFTAYSQCFRSEAGSAGQDTRGMIRQHQFSKVELVSITDASQSNVELERMLSVAEEVLKRLELPYRVVLLC
TGDMGFSASISYDIEVWMPAQNKYREISSCSNCKDFQARRMGAKCFYLEKQNKRSSFVHTLNGSALALGRTIAAIMENYQ
NSDGTITIPDALRKFMSADYIRPGTALP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-88 47