Gene Information

Name : guaA (Saro_0550)
Accession : YP_495831.1
Strain : Novosphingobium aromaticivorans DSM 12444
Genome accession: NC_007794
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 600682 - 602304 bp
Length : 1623 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAACTGTCACATTTGTCGCTCCATCTGGACAGAAACGGCCAGTGTGCTTATCGGCCAGCCATGAGCATCCAGCCTTC
AGAATCGATCCTGATCGTCGACTTCGGCAGCCAGGTTACCCAGCTAATCGCCCGCCGCGTGCGCGAGGCCGGGGTCTATT
CCGAGATCGCGCCCTTCAGCCAGGCCGAGGCGGCGTTCCACCGGATGAAGCCGAAGGGCATCATCCTGTCGGGATCGCCC
GCCAGCGTGCCCGCCGATGGCAGCCCGCGCGCACCTCAGGTGCTGTTCGACAGCGGCCTGCCGATCCTTGGCATCTGCTA
TGGCCAGCAGGTGATGAGCGAGCAGCTTGGCGGCAAGGTCGAGCCTGGCGATTCGGGCGAATTCGGCCGCGCCTTCCTGA
CCGTGACGGAACCCTGCGTACTGTTCGACGGCCTGTGGGCCGTGGGCGAACGCCACCAGGTATGGATGAGTCACGGCGAC
AAGGTGACGCAGTTCGCACCGGGCTTCCGCATCGTCGCCGTGTCCGACGGCGCGCCTTTTGCGGTGATCGCGAACGATGA
GAAGAAGTACTACGGAACCCAGTTCCACCCCGAAGTGGTGCACACGCCGGACGGTGGCAAGCTGATCGCCAATTTCGTGC
GCCATGTCTGCGGTTGCGCCGGCGACTGGTCGATGGCCGAGTTCCGCCGCACCAAGATCGCCGAGATCCGCGAGCAGGTG
GGCGACAGCCGGGTGATCTGCGGTCTTTCGGGCGGCGTCGATTCCGCCGTGGCGGCAGTGCTGATCCACGAGGCGATCGG
CGACCAGCTCACCTGCGTCTTCGTCGACCACGGCCTGATGCGCATGGGCGAGGCCGAGCAGGTCGTCAGCCTTTTCCGCA
ACCATTACAACATCCCGCTCGTCCACAAGGACGTGTCGGCCCTGTTCCTTGGCGGCCTCGCCGGGGTTACCGACCCCGAG
GCCAAGCGCAAGTTCATCGGCAAGACCTTCATCGACGTGTTCGAGGCCGAGGCCAGGCAGGTCGGCGGCGCGGACTTCCT
TGCGCAGGGCACGCTCTATCCGGACGTGATCGAATCGGTATCGTTCACCGGCGGGCCTTCGGTCACGATCAAGAGCCACC
ACAACGTCGGCGGCCTGCCCGAGCGCATGAACATGAAGCTGGTCGAGCCGCTTCGCGAGCTGTTCAAGGACGAAGTCCGC
GCGCTGGGCCGCGAGCTTGGCCTGCCCGAGATCTTCGTTGGTCGCCACCCCTTCCCCGGCCCGGGCCTTGCCATCCGCAT
CCCCGGCGAAGTGACGAAGGAGCGCTGCGACATCCTGCGCAAGGCCGACGCGATCTATCTCGAGGAGATCCGCAACGCGG
GCCTTTATGACGCGATCTGGCAGGCCTTTGCCGTGCTGCTTCCGGTCAAGACCGTGGGCGTTATGGGCGACGGGCGCACT
TATGACAGTGTCTGCGCACTGCGCGCGGTGACCAGCACCGACGGCATGACCGCCGACATCTATCCGTTCGACGCAGGCTT
CCTGAGCCGCGTGGCGACGCGCATCGTCAACGAGGTCAAGGGCATCAACCGCGTGGTCTACGACTACACCTCGAAGCCGC
CGGGCACGATCGAGTGGGAGTAA

Protein sequence :
MQLSHLSLHLDRNGQCAYRPAMSIQPSESILIVDFGSQVTQLIARRVREAGVYSEIAPFSQAEAAFHRMKPKGIILSGSP
ASVPADGSPRAPQVLFDSGLPILGICYGQQVMSEQLGGKVEPGDSGEFGRAFLTVTEPCVLFDGLWAVGERHQVWMSHGD
KVTQFAPGFRIVAVSDGAPFAVIANDEKKYYGTQFHPEVVHTPDGGKLIANFVRHVCGCAGDWSMAEFRRTKIAEIREQV
GDSRVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLMRMGEAEQVVSLFRNHYNIPLVHKDVSALFLGGLAGVTDPE
AKRKFIGKTFIDVFEAEARQVGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVR
ALGRELGLPEIFVGRHPFPGPGLAIRIPGEVTKERCDILRKADAIYLEEIRNAGLYDAIWQAFAVLLPVKTVGVMGDGRT
YDSVCALRAVTSTDGMTADIYPFDAGFLSRVATRIVNEVKGINRVVYDYTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-131 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-131 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-131 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-117 52