Gene Information

Name : metB (SAUSA300_0434)
Accession : YP_493147.1
Strain : Staphylococcus aureus FPR3757
Genome accession: NC_007793
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 487344 - 488486 bp
Length : 1143 bp
Strand : +
Note : identified by match to protein family HMM PF00266; match to protein family HMM PF01053

DNA sequence :
ATGAACAAGAAAACTAAATTAATTCATGGTGGGCACACAACAGACGATTATACAGGTGCCGTTACAACACCAATTTATCA
AACAAGTACATATTTACAAGATGATATTGGTGATTTACGTCAAGGATATGAATATTCTCGTACTGCGAATCCAACAAGAA
GTTCTGTAGAAAGCGTTATTGCGACATTAGAAAATGGCAAACATGGCTTTGCATTTAGTTCAGGTGTTGCAGCAATCAGT
GCAGTTGTTATGCTGTTGGACAAAGGAGATCATATTATTTTAAATTCAGATGTATACGGCGGTACTTATCGCGCATTGAC
AAAAGTATTTACACGATTTGGCATTGAAGTGGATTTTGTAGATACAACGCATACAGATTCAATTGTACAAGCGATACGCC
CAACAACAAAGATGTTGTTTATTGAAACACCTTCTAATCCATTATTACGTGTTACTGACATTAAAAAGTCTGCTGAAATT
GCGAAAGAACACGGTTTGATTTCAGTTGTTGATAACACATTTATGACACCTTATTATCAGAATCCATTAGATTTAGGTAT
CGATATTGTCTTACATTCTGCAACGAAATATTTAGGTGGACATAGTGATGTCGTTGCTGGTTTAGTTGCAACATCGGATG
ACAAGCTTGCAGAACGTTTAGCATTTATTTCAAATTCAACAGGTGGCATTTTAGGACCTCAAGATAGCTATTTACTTGTG
AGGGGTATTAAAACATTAGGTTTACGTATGGAACAAATTAATCGCAGCGTTATTGAAATTATTAAAATGTTACAAGCACA
TCCAGCTGTGCAACAAGTGTTCCATCCAAGTATTGAAAGTCATTTAAATCATGATGTCCATATGGCTCAAGCGGATGGCC
ATACAGGTGTGATTGCATTTGAAGTGAAAAATACAGAAAGTGCCAAACAATTGATTAAAGCAACATCGTATTACACATTA
GCTGAAAGTTTAGGTGCAGTGGAAAGTTTAATTTCAGTACCTGCATTGATGACACATGCATCCATTCCAGCAGATATTCG
AGCTAAAGAAGGTATTACAGACGGACTTGTAAGAATTTCTGTAGGTATTGAAGATACTGAAGATTTAGTCGATGATTTAA
AACAAGCACTAGATACTTTATAA

Protein sequence :
MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYEYSRTANPTRSSVESVIATLENGKHGFAFSSGVAAIS
AVVMLLDKGDHIILNSDVYGGTYRALTKVFTRFGIEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEI
AKEHGLISVVDNTFMTPYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAERLAFISNSTGGILGPQDSYLLV
RGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHPSIESHLNHDVHMAQADGHTGVIAFEVKNTESAKQLIKATSYYTL
AESLGAVESLISVPALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-177 99
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-178 99
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-78 44