Gene Information

Name : SAUSA300_0033 (SAUSA300_0033)
Accession : YP_492753.1
Strain : Staphylococcus aureus FPR3757
Genome accession: NC_007793
Putative virulence/resistance : Resistance
Product : methicillin-resistance MecR1 regulatory protein
Function : -
COG functional category : K : Transcription
COG ID : COG4219
EC number : -
Position : 41233 - 42219 bp
Length : 987 bp
Strand : +
Note : identified by match to protein family HMM PF05569

DNA sequence : 
GTGTTATCATCTTTTTTAATGTTAAGTATAATCAGTTCATTGCTCACGATATGTGTAATTTTTTTAGTGAGAATGCTCTA
TATAAAATATACTCAAAATATTATGTCACATAAGATTTGGTTATTAGTGCTCGTCTCCACGTTAATTCCATTAATACCAT
TTTACAAAATATCGAATTTTACATTTTCAAAAGATATGATGAATCGAAATGTATCTGACACGACTTCTTCGGTTAGTCAT
ATGTTAGATGGTCAACAATCATCTGTTACGAAAGACTTAGCAATTAATGTTAATCAGTTTGAGACCTCAAATATAACGTA
TATGATTCTTTTGATATGGGTATTTGGTAGTTTGTTGTGCTTATTTTATATGATTAAGGCATTCCGACAAATTGATGTTA
TTAAAAGTTCGTCATTGGAATCGTCATATCTTAATGAACGACTTAAAGTATGTCAAAGTAAGATGCAGTTCTACAAAAAG
CATATAACAATTAGTTATAGTTCAAACATTGATAATCCGATGGTATTTGGTTTAGTGAAATCCCAAATTGTACTACCAAC
TGTCGTAGTCGAAACCATGAATGACAAAGAAATTGAATATATTATTCTACATGAACTATCACATGTGAAAAGTCATGACT
TAATATTCAACCAGCTTTATGTTGTTTTTAAAATGATATTCTGGTTTAATCCTGCACTATATATAAGTAAAACAATGATG
GACAATGACTGTGAAAAAGTATGTGATAGAAACGTTTTAAAAATTTTGAATCGCCATGAACATATACGTTATGGTGAATC
GATATTAAAATGCTCTATTTTAAAATCTCAGCACATAAATAATGTGGCAGCACAATATTTACTAGGTTTTAATTCAAATA
TTAAAGAACGTGTTAAGTATATTGCACTTTATGATTCAATGCCTAAACCTAATCGAAACAAGCGTATTGTTGCGTATATT
GTATGTAGTATATCGAGCTTCACATGA

Protein sequence : 
MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSH
MLDGQQSSVTKDLAINVNQFETSNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMM
DNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYI
VCSISSFT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecR1 YP_184945.1 methicillin-resistance MecR1 regulatory protein Not tested Type-I SCCmec Protein 2e-145 100
SAMSHR1132_00330 YP_005324557.1 methicillin resistance protein MecR (fragment) Not tested Type-IIIinv SCCmec Protein 2e-145 100
MW0032 NP_644847.1 truncated methicillin resistance protein MecR1 Not tested Type-IV SCCmec Protein 2e-145 100
SAUSA300_0033 YP_492753.1 methicillin-resistance MecR1 regulatory protein Not tested Type-IV SCCmec Protein 2e-145 100
mecR1 BAC67567.1 signal transducer protein MecR1 Not tested Type-IVc SCCmec Protein 2e-145 100

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAUSA300_0033 YP_492753.1 methicillin-resistance MecR1 regulatory protein NC_010079.5775297.p0 Protein 8e-141 100
SAUSA300_0033 YP_492753.1 methicillin-resistance MecR1 regulatory protein NC_003923.1004784.p0 Protein 1e-145 100
SAUSA300_0033 YP_492753.1 methicillin-resistance MecR1 regulatory protein NC_007793.3913613.p0 Protein 1e-145 100
SAUSA300_0033 YP_492753.1 methicillin-resistance MecR1 regulatory protein NC_002951.3236764.p0 Protein 1e-145 100