Gene Information

Name : hysA (SAUSA300_2161)
Accession : YP_494797.1
Strain : Staphylococcus aureus FPR3757
Genome accession: NC_007793
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2338092 - 2340515 bp
Length : 2424 bp
Strand : +
Note : identified by match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124

DNA sequence :
ATGACATATAGAATAAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTGTTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAATTGAGGA
ACACATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAATAATCCAGATATGAAGAAGAAGTTTGATGCTACA
GAGAAAGAGGCGACGAATTTACTCAAGGAAATGAAAACTGAAAGTGGTAGGAAATACTTGTGGTCAGGAGCGGAAACCCT
TGAAACTAATTCTTCTCATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAGGAATCCTAAAACCA
CTTTAAATACTGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAAAAAAGTAAAAGAATTAAGTGAGAATTTTACTAAAACAACTGGCAAGAATACCAACTTAAATTGGTGGGATTATGA
AATTGGAACACCTAAATCATTAACAAATACGCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAAAATTCA
CTGCCCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGAAAAGCTGAACTTGCTAAAGGCGGA
AATCTAGTAGACATTTCTAAGGTGAAACTTTTAGAATGTATTATCGAAGAAGATAAAGATATGATGAAAAAGTCTATAGA
TTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGGTAAAGAACGTAATGGATTTTATAAAGATGGCTCTT
ACATTGATCATCAAGACGTTCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCGATG
ATAAAAGAAACACCTTTTAATGATAAAACCCAAAATGATACAACCTTAAAGTCATGGATTGACGACGGATTTATGCCACT
CATTTATAAAGGTGAAATGATGGATTTATCACGAGGTAGAGCTATCAGTCGTGAAAATGAAACCAGTCACTCAGCATCTG
CAACAGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAAAAGATTGTCAAA
TCTTCAGTAGAGTCAGATTCAAGTTATAAACAAAATGATTATTTAAATTCATATTCGGACATAGATAAAATGAAGTCTTT
AATGACAGATAACAGTATTTCTAAAAACGGATTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCTATC
ATAACAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTAGCACGCTATGAAAGTATCAACGGAGAG
AATTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATATAACAGCGATGTCAAACACTATCATGATAACTTCTG
GGTGACAGCCGATATGAAACGTTTATCAGGTACAACAACTTTAGACAATGAAATATTAAAAGATACGGATGATAAAAAGT
CGAGTAAAACTTTTGTTGGCGGAACAAAAGTTGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGACAAA
ACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGATTC
ATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAACCA
ATTCTGATAATCAGGAAAACAATTCAGTCTTTTTAGAGTCCACAGATACCAAAAAGAACATCGGTTATCATTTTTTAAAC
AAACCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAAAGAAATAAATAAAAGTCAAAAGGATACACAAAA
AACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATTCTGACAATAAATATGGATATGTGTTGTATCCAGGCTTAT
CTAAAGATGTCTTTAAGACAAAAAAAGATGAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTGAAAGATAAT
GAATCGGTTTGGGCTGGTGTTAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGAAGTTAAAGC
CAAAGGTATGTTTATACTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCTGAATCTACAAATTCCG
CTTCAGATATTGAATCTAAAATTTCAATGACCGGTTACTCTATTACAAACAAAAATACGTCGACTTCTAATGAATCCGGC
GTGCACTTTGAATTAACTAAATAA

Protein sequence :
MTYRIKKWQKLSTITLLMAGVITLNGGEFRSVDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDENNPDMKKKFDAT
EKEATNLLKEMKTESGRKYLWSGAETLETNSSHMTRTYRNIEKIAEAMRNPKTTLNTDENKKKVKDALEWLHKNAYGKEP
DKKVKELSENFTKTTGKNTNLNWWDYEIGTPKSLTNTLILLNDQFSNEEKKKFTAPIKTFAPDSDKILSSVGKAELAKGG
NLVDISKVKLLECIIEEDKDMMKKSIDSFNKVFTYVQDSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPM
IKETPFNDKTQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIVK
SSVESDSSYKQNDYLNSYSDIDKMKSLMTDNSISKNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESINGE
NLKGWHTGAGMSYLYNSDVKHYHDNFWVTADMKRLSGTTTLDNEILKDTDDKKSSKTFVGGTKVDDQHASIGMDFENQDK
TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTNSDNQENNSVFLESTDTKKNIGYHFLN
KPKITVKKESHTGKWKEINKSQKDTQKTDEYYEVTQKHSNSDNKYGYVLYPGLSKDVFKTKKDEVTVVKQEDDFHVVKDN
ESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSASDIESKISMTGYSITNKNTSTSNESG
VHFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_494797.1 hyaluronate lyase VFG1315 Protein 0.0 88