Gene Information

Name : hsdM (SAUSA300_1752)
Accession : YP_494443.1
Strain : Staphylococcus aureus FPR3757
Genome accession: NC_007793
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 1936836 - 1938575 bp
Length : 1740 bp
Strand : -
Note : identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497

DNA sequence :
ATGATTTTGAAAGCATTTGAAAGCTACAACATTTCTATAAAATTTTTCAATAACAATTGCGCCACTAAAACTCAAAATTT
CCACCACCAACATCCAAATTATCAACATCGCAACATAACCAAATGTTATAATAAATCTATTACACAAAGAGATAAATTAC
TTATGCAAAGGCGGAGGAATCACATGTCTATTACTGAAAAACAACGTCAGCAACAAGCTGAATTACATAAAAAATTATGG
TCGATTGCGAATGATTTAAGAGGGAACATGGATGCGAGTGAATTCCGTAATTACATTTTAGGCTTGATTTTCTATCGCTT
CTTATCTGAAAAAGCCGAACAAGAATATGCAGATGCCTTGTCAGGTGAAGACATCACGTATCAAGAAGCATGGGCAGATG
AAGAATATCGTGAAGACTTAAAAGCAGAATTAATTGATCAAGTCGGTTACTTCATTGAGCCACAAGATTTATTCAGTGCG
ATGATTCGTGAAATTGAAACGCAAGATTTCGATATAGAACATCTAGCGACGGCGATTCGCAAAGTTGAAACATCTACATT
AGGTGAAGAAAGTGAAAATGACTTTATCGGGCTGTTCAGCGATATGGATTTGAGTTCAACGCGACTAGGTAACAATGTCA
AAGAACGTACTGCTTTAATCTCTAAAGTCATGGTTAATCTTGACGACTTACCATTCGTTCACAGTGACATGGAAATTGAT
ATGTTAGGTGATGCATATGAATTCCTAATCGGGCGCTTTGCGGCGACAGCGGGTAAAAAAGCAGGCGAGTTCTATACACC
ACAACAAGTATCTAAGATACTGGCGAAGATTGTCACAGACGGTAAAGATAAATTACGTCACGTGTATGACCCAACATGTG
GTTCAGGTTCACTGTTGTTACGTGTTGGTAAAGAAACACAAGTGTATCGTTATTTCGGTCAAGAACGTAACAATACTACA
TACAACTTAGCACGCATGAATATGTTATTACATGATGTGCGTTATGAGAACTTCGATATCCGTAATGATGACACATTGGA
AAACCCAGCCTTTTTAGGCAATACATTTGATGCGGTTATTGCGAACCCACCGTATAGTGCGAAATGGACTGCAGATTCAA
AGTTTGAAAATGACGAACGATTCAGTGGTTACGGCAAACTTGCGCCTAAGTCTAAAGCAGACTTTGCCTTTATTCAACAC
ATGGTACATTACCTAGACGATGAAGGTACCATGGCCGTTGTACTCCCACATGGTGTATTATTCCGAGGTGCTGCAGAAGG
TGTCATTCGTCGTTATTTAATTGAAGAAAAGAACTACTTAGAAGCTGTGATTGGTTTGCCAGCGAATATTTTCTATGGGA
CAAGTATTCCAACATGTATTTTAGTATTTAAAAAATGTCGCCAACAAGACGACAACGTACTATTTATCGATGCATCCAAT
GATTTTGAAAAAGGAAAAAATCAAAATCATTTAAGCGATGCCCAAGTCGAACGTATTATAGACACATATAAGCGTAAGGA
AACAATTGATAAATATAGCTACAGCGCGACACTACAAGAGATTGCCGATAACGATTACAACCTAAATATACCGAGATATG
TCGATACATTCGAAGAAGAAGCACCGATTGATTTAGATCAAGTCCAACAAGATTTGAAAAATATCGATAAAGAAATCGCA
GAAATTGAGCAAGAAATCAATGCATACCTGAAAGAACTTGGGGTGTTGAAAGATGAGTAA

Protein sequence :
MILKAFESYNISIKFFNNNCATKTQNFHHQHPNYQHRNITKCYNKSITQRDKLLMQRRRNHMSITEKQRQQQAELHKKLW
SIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADALSGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSA
MIREIETQDFDIEHLATAIRKVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLLRVGKETQVYRYFGQERNNTT
YNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNTFDAVIANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQH
MVHYLDDEGTMAVVLPHGVLFRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
DFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLNIPRYVDTFEEEAPIDLDQVQQDLKNIDKEIA
EIEQEINAYLKELGVLKDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 0.0 100
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 0.0 100
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 0.0 100
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 0.0 99
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 0.0 99
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 0.0 99
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 0.0 99
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 0.0 99
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 0.0 99
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 0.0 99
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 0.0 99
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 0.0 99
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 0.0 99
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 0.0 99
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 0.0 99
ORF6 BAC22943.1 - Not tested etd PI Protein 0.0 99
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 0.0 99
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 0.0 99
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 0.0 99
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 0.0 99
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 0.0 98
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 0.0 86