Gene Information

Name : ermC (SAUSA300_pUSA030007)
Accession : YP_492693.1
Strain :
Genome accession: NC_007792
Putative virulence/resistance : Resistance
Product : rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein)
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0030
EC number : 2.1.1.48
Position : 7865 - 8599 bp
Length : 735 bp
Strand : +
Note : identified by match to protein family HMM PF00398

DNA sequence : 
ATGAACGAGAAAAATATAAAACACAGTCAAAACTTTATTACTTCAAAACATAATATAGATAAAATAATGACAAATATAAG
ATTAAATGAACATGATAATATCTTTGAAATCGGCTCAGGAAAAGGGCATTTTACCCTTGAATTAGTACAGAGGTGTAATT
TCGTAACTGCCATTGAAATAGACCATAAATTATGCAAAACTACAGAAAATAAACTTGTTGATCACGATAATTTCCAAGTT
TTAAACAAGGATATATTGCAGTTTAAATTTCCTAAAAACCAATCCTATAAAATATTTGGTAATATACCTTATAACATAAG
TACGGATATAATACGCAAAATTGTTTTTGATAGTATAGCTGATGAGATTTATTTAATCGTGGAATACGAGTTTGCTAAAA
GATTATTAAATACAAAACGCTCATTGGCATTATTTTTAATGGCAGAAGTTGATATTTCTATATTAAGTATGGTTCCAAGA
GAATATTTTCATCCTAAACCTAAAGTGAATAGCTCACTTATCAGATTAAATAGAAAAAAATCAAGAATATCACACAAAGA
TAAACAGAAGTATAATTATTTCGTTATGAAATGGGTTAACAAAGAATACAAGAAAATATTTACAAAAAATCAATTTAACA
ATTCCTTAAAACATGCAGGAATTGACGATTTAAACAATATTAGCTTTGAACAATTCTTATCTCTTTTCAATAGCTATAAA
TTATTTAATAAGTAA

Protein sequence : 
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQV
LNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYEFAKRLLNTKRSLALFLMAEVDISILSMVPR
EYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYK
LFNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 5e-110 99
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 3e-62 57
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 3e-62 57
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 3e-62 57
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 3e-62 57
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 3e-62 57
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 3e-62 57
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 7e-62 56
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 7e-62 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_007792.3912746.p0 Protein 1e-110 100
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_007209.3523503.p0 Protein 3e-110 99
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_010686.6295746.p0 Protein 3e-110 99
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_010685.6295744.p0 Protein 3e-110 99
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) V01278.gene.p01 Protein 6e-109 98
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) M64090.gene.p01 Protein 1e-87 77
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) AJ313523.1.orf0.gene Protein 4e-81 75
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) M15332.gene.p01 Protein 2e-81 71
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002952.2859614.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002745.1122822.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002745.1124324.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002745.1125313.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_009782.5559087.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002758.1121630.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002952.2859615.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002745.1123579.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002745.1124852.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_009782.5559229.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) NC_002758.1120012.p0 Protein 2e-62 57
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) AM180355.1.gene2259. Protein 2e-56 50
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) AM903082.gene3.p01 Protein 1e-56 50
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) AM180355.1.gene2254. Protein 2e-56 50
ermC YP_492693.1 rRNA adenine N-6-methyltransferase (macrolide-lincosamide-streptogramin B resistance protein) AM410044.gene14.p01 Protein 1e-56 50