Gene Information

Name : guaA (RPB_3189)
Accession : YP_486796.1
Strain : Rhodopseudomonas palustris HaA2
Genome accession: NC_007778
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3646204 - 3647826 bp
Length : 1623 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGCCCCCAGCACACCCTCCGCTTCGTCCGTCGTCCCCTCCGGCGCCGACACCTCGCCGCATGTCGCAGCGATCCA
CGAGAAGATCCTGATCGTCGATTTCGGCTCGCAGGTCACCCAGCTGATCGCCCGCCGCGTCCGCGAGGAGGGCGTCTATT
CCGAGATCGTGCCGTTCCAGAAGGCGGAGGCCGCCTTCGCCGAGATGAAGCCGAAGGCCGTGATCCTGTCCGGCGGCCCG
GCCTCGGTGCTCGACGCCGACGCGCCCGCTGCGCCGATGGCGATCCTCGAGGCCGGCGTGCCGGTGCTCGGGATCTGCTA
CGGTGAACAGACGCTGGCCAAGCAGCTCGGCGGCACGGTCGAAGCCGGCCATCACCGCGAATTCGGCCGCGCCACGATCG
AGATCACCGACGACTGCGCGCTGTTCGACGGCGTCTGGCAGAAGGGCGGCACATACGACGTCTGGATGAGCCATGGCGAC
CGCGTCACCAAGCTGCCCGACGGCTTCCGCGGCGTCGCCAAGGCGCCGGGCTCGCCGATCTCGGTGATCGCCGACGACAA
ACGCAAGTTCTACGCGACGCAGTTCCATCTCGAAGTGGTGCACACGCCGGACGGCGCGAAAATCCTGCGCAACTTCGTCC
GCAAGGTCGCGGGGCTGACCGGCGACTGGACGATGCGCGCCTTCCGCGAGGAGGCGATCGAGAAGATCCGCGCGCAGGTC
GGCACCGGCAAGGTGATCTGCGGCCTGTCCGGCGGCGTCGACTCGGCGGTCGCCGCGGTGCTGATCCATGAGGCGATCGG
CGATCAGCTCACCTGCGTGTTCGTCGACCACGGCATGCTGCGCAAGGACGAGGCCAAGACCGTCGTCGACCTGTTCCGGC
ATCACTACAACATCCCGCTGGTGCATGTGGACGCGTCGGAGACCTTCCTCGGCGCGCTCAGCGGCGTTACCGATCCGGAG
CAGAAGCGCAAGATCATCGGCAAGCTGTTCATCGACGTGTTCGACGCCGAGGCCAAGGTCGTCGGCGGCGCTGATTACTT
GGCGCAAGGCACGCTGTATCCCGACGTGATCGAGAGCGTGTCGTTCACCGGCGGCCCGTCGGTGACGATCAAGTCGCACC
ACAATGTCGGCGGCCTGCCCGAACGCATGAACATGAAGCTGGTCGAACCCTTGCGCGAATTGTTCAAGGACGAGGTGAGG
GCGCTCGGCCGCGAGCTCGGCCTGCCGGAGATTTTCGTCGGCCGCCACCCGTTCCCGGGCCCGGGCCTGGCCATCCGCTG
CCCCGGCGAGATCACCGCCGAGAAGCTCGACATCCTGCGCAACGCCGACGCGGTGTATATCGACCAGATCCGCAAGGCCG
GCCTCTACGACGCGATCTGGCAGGCCTTCGCGGTGCTGCTGCCGGTCAAGACCGTCGGCGTGATGGGCGACGGCCGCACC
TACGAGTACGTCGTCGGCCTGCGCGCCGTGACCTCGACCGACGGCATGACGGCCGATTACTACCCGTTCGACATGGCCTT
CCTGGGCGCCACCGCGACCCGGATCATCAACGAGGTCAAGGGCGTCAACCGCGTGGTCTACGACGTGACCAGCAAGCCGC
CGGGGACCATCGAGTGGGAGTGA

Protein sequence :
MTAPSTPSASSVVPSGADTSPHVAAIHEKILIVDFGSQVTQLIARRVREEGVYSEIVPFQKAEAAFAEMKPKAVILSGGP
ASVLDADAPAAPMAILEAGVPVLGICYGEQTLAKQLGGTVEAGHHREFGRATIEITDDCALFDGVWQKGGTYDVWMSHGD
RVTKLPDGFRGVAKAPGSPISVIADDKRKFYATQFHLEVVHTPDGAKILRNFVRKVAGLTGDWTMRAFREEAIEKIRAQV
GTGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGMLRKDEAKTVVDLFRHHYNIPLVHVDASETFLGALSGVTDPE
QKRKIIGKLFIDVFDAEAKVVGGADYLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVR
ALGRELGLPEIFVGRHPFPGPGLAIRCPGEITAEKLDILRNADAVYIDQIRKAGLYDAIWQAFAVLLPVKTVGVMGDGRT
YEYVVGLRAVTSTDGMTADYYPFDMAFLGATATRIINEVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-132 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-132 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-132 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-119 50