Gene Information

Name : thyA (RPB_2036)
Accession : YP_485654.1
Strain : Rhodopseudomonas palustris HaA2
Genome accession: NC_007778
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2316065 - 2316859 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATTCCGTACCACGACCTGCTCGAACGCATCCTGAGCGACGGCGCCGAAAAACACGACCGCACCGGCACCGGCACGCT
GTCGGTGTTCGGCCATCAGCTTCGGTTCGATCTCGCCGCCGGTTTTCCGATGCTGACCACCAAGCGGTTACCGCTCAAGG
CGATCATTCACGAGCTGCTGTGGTTTCTGCAGGGCGACACCAACATCAAATATCTGCACGACCACGGCGTCACGATCTGG
GACGAATGGGCGGACGCCAACGGTGACCTCGGCCCTGTCTATGGCGCGCAATGGCGCTCGTGGCCGACCGCGGACGGCCG
CAGCATCGATCAGATCGCCCATGTCGTCGACATGATCAGGCGCAACCCGGACTCGCGTCGGCTGATCGTCACGGCGTGGA
ATCCGGCGGATGTCGAGAAGATGGCGTTGCCGCCGTGTCATTGCCTGTTCCAGTTCTACGTCGCGAACGGCAGGCTATCG
TGCCAATTGTATCAGCGCTCGGCGGACGTGTTTCTCGGCGTGCCGTTCAACATCGCGTCCTACGCGCTGCTGACGATGAT
GGTGGCGCAGGTCACGGGGCTGAAGCCCGGCGACTTCATCCACACGCTCGGCGACGCGCATCTGTATTCCAATCATCTGG
AGCAGGCGCGGCTGCAACTGACCCGCGCCCCGCGCGCGCTGCCGGCGATGGCGATCAATCCCGCCGTGACCGACATCTTC
GGCTTCCGCTACGAAGACTTCACCCTGCACGGCTACGATCCGCACCCGCACATCAAGGCGGAGGTGGCGGTGTGA

Protein sequence :
MIPYHDLLERILSDGAEKHDRTGTGTLSVFGHQLRFDLAAGFPMLTTKRLPLKAIIHELLWFLQGDTNIKYLHDHGVTIW
DEWADANGDLGPVYGAQWRSWPTADGRSIDQIAHVVDMIRRNPDSRRLIVTAWNPADVEKMALPPCHCLFQFYVANGRLS
CQLYQRSADVFLGVPFNIASYALLTMMVAQVTGLKPGDFIHTLGDAHLYSNHLEQARLQLTRAPRALPAMAINPAVTDIF
GFRYEDFTLHGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-84 63