Gene Information

Name : ureB (Francci3_0833)
Accession : YP_479946.1
Strain : Frankia sp. CcI3
Genome accession: NC_007777
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0832
EC number : 3.5.1.5
Position : 973083 - 973463 bp
Length : 381 bp
Strand : -
Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzym

DNA sequence :
GTGATCCCCGGGGAGATCCTGACCGGCGACGATCCCGTCGAGATCAACGCCGGACGCCCGGTACGCACGGTGCTGGTCCG
TAACATGGGCGACCGGCCGGTGCAGGTCGGCTCGCACTACCACTTCGCCGCGGCGAACCCCGCTCTCGACTTCGACCGGG
CGAGTGCCTGGGGCCACCGGCTCGCGGTGCCCGCCGGCACCGCGGTCCGCTTCGAACCCGGCGTGGAACGCGAGATCGAA
CTGGTGCCGCTGGCCGGCGCCCGGGTCGTGCCGGGCCTGCGGCCGGAATCGGCCGGCCCGTTGGACGCCGCGAGCGGCAC
CCGGATTGCGGACACCGCGACGATCGAGGATATATCGGGCTTTCAGGGAGAGGGTTCGTGA

Protein sequence :
MIPGEILTGDDPVEINAGRPVRTVLVRNMGDRPVQVGSHYHFAAANPALDFDRASAWGHRLAVPAGTAVRFEPGVEREIE
LVPLAGARVVPGLRPESAGPLDAASGTRIADTATIEDISGFQGEGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureB NP_286679.1 urease subunit beta Virulence TAI Protein 3e-26 58
ureB NP_287087.1 urease subunit beta Not tested TAI Protein 3e-26 58
ureB YP_005682175.1 Urease beta subunit Not tested PiCp 7 Protein 4e-22 56
ureB YP_005684267.1 Urease beta subunit Not tested PiCp 7 Protein 4e-22 56
ureB YP_005686359.1 Urease beta subunit Not tested PiCp 7 Protein 4e-22 56
ureB YP_003784326.1 urease subunit beta Not tested PiCp 7 Protein 3e-22 56