Gene Information

Name : leuS (Francci3_3901)
Accession : YP_482980.1
Strain : Frankia sp. CcI3
Genome accession: NC_007777
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4667018 - 4670212 bp
Length : 3195 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCACGAGCGATGAGTGAGACGGCCGAGCCCGGCGCCCGGACCGGCGCCGCGGACACCACGGTGGCACCGACCGGTGC
GTCTGGCGGGATCATCCCGGCAGCCGCGGGCACCGCGGGCGGCGCCCCCGCCGGGACCGGGAGCGTCGAGCCGAGCTTCC
GGTACGACGCCCGGCTCGCCGCCGACATCGAGCGGCGCTGGCAGCGCCGGTGGGCCGACGAGGGCACGTTCAACTCGCCG
AACCCGGTCGGGCCGCTCTCGACGGGCTTCGAGAAGGTCGCCGGCCGGGAGCCGTTCTACATCATGGACATGTTCCCCTA
TCCGAGCGGCTCGGGGCTGCACGTCGGGCACCCGCTGGGGTACATCGGCACCGACGTGTTCGCCCGCTATCTGCGGATGT
CCGGCCGGCACGTGCTGCATCCGTTCGGATACGACTCCTTCGGCCTGCCCGCCGAGCAGTACGCCATCAACACGGGCCAG
CATCCCCGCGACACCACCAACGCCAACATCGCCAACATGCGCCGCCAACTCTCCCGGCTGGGGCTGGGCCACGACACCCG
CCGCGAGATCGCGACGACCGACGTGGGCTACTACCGCTGGACGCAGTGGATCTTCCAGCAGATCTTCAACAGCTGGTACG
ACCCGCAGGCCGGCCGGGCCCGGCCGATCGCCGAGCTGATCGAGGAGTTCGCCGCGGGCACCCGGGCGCCGGTAGCCGGC
CCCGCCGGGGGGAACACGGCCGTGTCGGTTGACGCGGTCCGGGCGGCGAACCCGGCCGGGCTGGCGTGGACCGAACTCGA
CGAGGTGTCCCGCCGGAAGGTCGTCAACGCGCACCGCCTGGCCTACATCTCCGAACAGCTGGTCAACTGGTGCCCGGGGC
TGGGCACCGTGCTGGCGAACGAGGAGGTCACCGCCGACGGCCGCAGCGACATCGGGAACTACCCAGTGTTTCGCCGGCCG
CTGAAGCAGTGGATCCTGCGGATCACCGCCTATGCCGAGCGGCTGATCTCCGACCTCGACCTGGTCGACTGGCCGGACTC
GATCAAGCAGATGCAGCGCAACTGGATCAGTCCGAGCGAGGGCGCCAGCGTCGAGTTCACCGTCGTCGCCCCCGGCGAGG
AGGCAGGTGCGTCCGATCCGTCTGGCTCATCGACCGCCCGGCGTATCGAGGTCTATACCACCCGCCCGGACACCCTGGCG
GGGGCCACCTTCCTGGTACTCGCGCCCGAACATCCCCTGGCCGACGCCCTGATCGCCGACACCTGGCCGGCGGACACCCC
GGTGAGCTGGCGCTTCCCGGCGGGACGGCCGGGCGGCGGCACGGAACCGGCGGACACCGCCGGGCCGGAGGCGGGCGCCG
ATCCGGCGTGGACCCCGCGAGCCGCCGTCGACGCCTACCGGGAGTTCGCGGCCCACCGCAGCGACCGGCAGCGCGGCGAG
GAGGTCATCGACCGCACCGGCGTGTTCACCGGCTCGTACGTGCGCAACCCGGTCGGTGGCGGGGTCATCCCGGTCTTCCT
GGCCGACTATGTGCTGCTGGGCTACGGCACCGGGGCAATCATGGCGGTACCGGCGCACGACAGCCGGGACTTCTCCTTCG
CCCGCGCGTTCGACCTGCCGATCCCCGCCGTGCTGGAGCCGGACGCGGACTGGTACGCCGCGCACGGGGTAGTGCCCGCG
ACTCCATCAGCGCAGTGGCCCGAGGCGTTCAGCGGTGCGGGCGAGTATCGGCCCGGTCCGGCCAGCGCCCCGGTGCTGGT
CGGCCTGTCGAAAAGCGAGGCGATCAAGGCCACGGTTCACTGGCTGGAGGAGATCGGCGCCGGCAGGTCGGCGCGGTCGT
ACCGGCTGCGGGACTGGCTGTTCTCCCGCCAGCGGTACTGGGGCGAGCCGTTCCCGATCGTCTTCGATGTCGACGGGCTG
CCCCACGCGGTTCCCGACGAGCTGCTGCCGATCGAACTGCCGGAGATGACCGACTTCCGGCCCACGGCGATGGCCGAGGA
CGACGCGAGCGACCCGGTGCCCCCCCTGGCCCGGGTGGCCGACTGGGTGACGGTCACCCTGGATCTCGGCGACGGGCCGA
AGCAGTACCGGCGCGAGACGAACACCATGCCGCAGTGGGCCGGTTCGTGTTGGTACTACCTGCGCTACCTGGACCCGACC
AACACCGAGCGCTTCGTCGACCCGACCGTCGAGCGCTACTGGATGGCCAGGCCGGGCGCGGTTCCCGGCGACGGCGGCGT
CGATCTGTACGTCGGCGGTGTCGAGCACGCCGTGCTGCACCTGCTCTACGCCCGGTTCTGGCACAAGGTGCTCTACGACC
TGGGCCACGTCTCCACCAAGGAGCCGTTCAAGCGGCTGTTCAACCAGGGATACATCCAGGCGGATGCCTTCACCGACGCC
CGGGGCATGTACGTCCCGGCGGCCGAGGTGACGGCGACCCCCGACGGCCGGTTCCTCTTCCAGGGCGCCCCGGTCAACCG
GCGCTCGGGCAAGATGGGCAAGAGCCTGAAGAACAGCGTCAGCCCGGACGAGATGTACGACAGGTTCGGCGCCGACACGC
TGCGCGTCTACGAGATGGCGATGGGCCCGCTCGACGCTGACCGGCCATGGCACACCGACGACATCGTCGGTTCGCACCGG
TTCCTCCAGCGGCTGTGGCGCACCGTCGTCGACGAAACCACCGGGGCGGCCGCCGTCGTTGACGAGCCGTTGGACGACGA
GGCTCTTCGCGTCCTGCACCGGACGATCCTCACGGTCACCGCCGAATACGCGGGGCTGCGGTTCAACACCGCGGTCGCCC
GGCTCATCGAACTAACCAACTTCGTCAGCAAGAGCTACGGGAAATCCCCCACCCCCCGCGCGCTCGCCGAGCCGCTCACC
CTGATGGCGGCCCCGCTGGCCCCGCACATCGCCGAGGAACTGTGGTCCCGCCTCGGTCACGAGGAGTCGGTCAGCACGGT
CGCCTTCCCGATCGGGGATCCGGCGCTGGCCGCCGAGTCGGTCAGGACGATCCCGGTCCAGGTGAACGGGAAGGTCCGGT
TCACCATCGAGGTTCCGGACGGTTCAGCGGAGCAGACGGTTCGCGATCTGCTCGCCGCACATCCCGAGTTCGCCCGGCAG
ACCGATGGTCGGACGATCAAGAAGATCATCGTCGTGCCCGGTCGGATCGTGAATATCGCCATCTCCCCCGCCTAG

Protein sequence :
MARAMSETAEPGARTGAADTTVAPTGASGGIIPAAAGTAGGAPAGTGSVEPSFRYDARLAADIERRWQRRWADEGTFNSP
NPVGPLSTGFEKVAGREPFYIMDMFPYPSGSGLHVGHPLGYIGTDVFARYLRMSGRHVLHPFGYDSFGLPAEQYAINTGQ
HPRDTTNANIANMRRQLSRLGLGHDTRREIATTDVGYYRWTQWIFQQIFNSWYDPQAGRARPIAELIEEFAAGTRAPVAG
PAGGNTAVSVDAVRAANPAGLAWTELDEVSRRKVVNAHRLAYISEQLVNWCPGLGTVLANEEVTADGRSDIGNYPVFRRP
LKQWILRITAYAERLISDLDLVDWPDSIKQMQRNWISPSEGASVEFTVVAPGEEAGASDPSGSSTARRIEVYTTRPDTLA
GATFLVLAPEHPLADALIADTWPADTPVSWRFPAGRPGGGTEPADTAGPEAGADPAWTPRAAVDAYREFAAHRSDRQRGE
EVIDRTGVFTGSYVRNPVGGGVIPVFLADYVLLGYGTGAIMAVPAHDSRDFSFARAFDLPIPAVLEPDADWYAAHGVVPA
TPSAQWPEAFSGAGEYRPGPASAPVLVGLSKSEAIKATVHWLEEIGAGRSARSYRLRDWLFSRQRYWGEPFPIVFDVDGL
PHAVPDELLPIELPEMTDFRPTAMAEDDASDPVPPLARVADWVTVTLDLGDGPKQYRRETNTMPQWAGSCWYYLRYLDPT
NTERFVDPTVERYWMARPGAVPGDGGVDLYVGGVEHAVLHLLYARFWHKVLYDLGHVSTKEPFKRLFNQGYIQADAFTDA
RGMYVPAAEVTATPDGRFLFQGAPVNRRSGKMGKSLKNSVSPDEMYDRFGADTLRVYEMAMGPLDADRPWHTDDIVGSHR
FLQRLWRTVVDETTGAAAVVDEPLDDEALRVLHRTILTVTAEYAGLRFNTAVARLIELTNFVSKSYGKSPTPRALAEPLT
LMAAPLAPHIAEELWSRLGHEESVSTVAFPIGDPALAAESVRTIPVQVNGKVRFTIEVPDGSAEQTVRDLLAAHPEFARQ
TDGRTIKKIIVVPGRIVNIAISPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-130 44