Gene Information

Name : leuS (CYB_2881)
Accession : YP_479064.1
Strain : Synechococcus sp. JA-2-3B'a(2-13)
Genome accession: NC_007776
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2979666 - 2982314 bp
Length : 2649 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGACGCGCGCTACAATCCCCAGGCCATCGAGAGCAAGTGGCAAGCCCACTGGCGTGAAATCGGGCTGGATCGCACCCC
AGAGCTGAAGGACGGGAGCCGCAAATTTTATGCTCTGTCCATGTTCCCCTATCCCAGCGGCAACCTGCACATGGGGCATG
TGCGCAATTACACCATCACCGATGTAATTGCCCGCCACAAACGAATGCAGGGATACGCGGTGTTGCACCCGATGGGCTGG
GATGCCTTTGGCCTGCCGGCGGAGAATGCCGCCATCGACCGGGGGATCCCACCGGCCAAGTGGACCTACCAAAACATTGC
CCAGATGCGGGAGCAACTGCAGCGGCTGGGGCTCTCCTACGACTGGGAGCGGGAGATCACCACCTGCGCCCCCGACTACT
ACAAGTGGACGCAGTGGCTCTTCCTGCAATTTTTCAAGGCCGGCCTGGCCTACCAGAAGGAAGCGCCAGTGAACTGGGAT
CCGGTGGATCAGACGGTGTTGGCCAACGAGCAGGTGGATGCGGAGGGGCGTTCCTGGAGATCCGGCGCCCTGGTGGAAAA
GCGCATGCTCAAGCAGTGGTTTTTCAAAATCACCGCCTATGCCGACCAACTGCTGGCGGATCTGGAAAAGCTCTCCGGCT
GGCCGGAGCGGGTGCGCACCATGCAGGAGAATTGGATTGGCCAATCGGTGGGGGCTAAGGTGATTTTCAAAACCGAGGCG
GGGGACGAGCTGGCAGTGTTCACCACCCGGCCCGATACCCTCTGGGGGGCCACCTTCATGGTGATGTCGCCGGAGCACCC
CTTGGTGGACAAGCTCACCACTGCCGAGCAACTGCAGGCCGTCAGAGCCTATCAAGCCCAGGCCGCTGCCCGCAGCGAGA
TCGAGCGCAGCGCTGAAGACCGGGAAAAGACAGGGGTTTGGACGGGATCCTACGCCATCAACCCCGTCAACCAAGAGCGA
ATCCCCATCTGGATTGCCGACTATGTGCTGATGGGCTACGGTACGGGGGCCATTATGGCCGTGCCTGCCCACGACCAGCG
GGATTTCGAGTTTGCCCGCAAGTTCGGCCTGCCCATCAAGCGGGTGGTGCAGCCGCCGGAGGGTTCCTTATCCTCGACGG
ATCGCGCCAGCGGGACGGAGTCCTCAGAACTGCAGGCTGCCTGGACGGGGGAAGGGGTGATGATCAACTCTGGCCCCCTA
GACGGGATCCCGGTGGGCAAAGGCCCAGGGCAAAGCGTGGAAAGAGCCATCGCCTGGCTGGAAGCCCAGGGGCTGGGGGA
AAAGCAGATCAACTACCGCCTGCGGGATTGGCTGATCTCGCGGCAGCGCTACTGGGGTTGTCCCATCCCGGTGATCCATT
GTCCCCACTGTGGCATTGTGCCGGTGCCGGAGAAGGATCTGCCGGTGCTCTTGCCGGAGGATGTGGAGCTGACGGGGCGA
GGGGGATCCCCGTTGGCCCAGTTGGAGGACTGGGTGAAGGTGAAGTGCCCCACCTGTGGCGCGGAGGCTCGCCGGGAAAC
CGATACCATGGACACCTTCATCTGCTCGTCGTGGTACTTCCTGCGCTTTAGCGATGCCCGCAACGACCGAGAGATCTTCC
GCAAAGACCGGGTGAACGCCTGGCTGCCGGTGGATCAGTACGTGGGCGGCATCGAGCACGCCATCCTGCACCTGCTCTAT
TCCCGCTTTTTTACCAAGGTGTTGCGGGATCGGGGGCTGCTGGATTTTGACGAGCCGTTCCTGCGTCTGCTCACCCAGGG
GATGGTGCAAGGGCGCACTTACTACAACCCCAACAAGTCCGGCAAGGATCGCTGGATCCCGGCAGCTCTGGTGAAGGATC
CCGACAACCCCACAGATCCGGAGACCGGCGAACCCCTGGAAGTGATCTATGCCACCATGTCCAAATCCAAGGGCAACGGC
GTGGATCCCGAGGAGGTGCTGGCCCACTACGGGGCGGATACGGCCCGCATGTTTATCCTCTTCAAGGCCCCGCCGGAGAA
GGATCTGGAGTGGGACGATGCCGATGTGGAGGGGCAATTTCGCTTTCTCAACCGCGTCTGGCGGCAGGTGTACGAGTTTG
TCGTTCGCGGTGGCGGGACGGAGTCCTGGCGGGGCAGGGTCTCAGAGCTGTTGCCGGCCAAGGTCGAGGTGGGATCCCTG
ACCAAGGCGGAAAAAGATCTGCGCCGGGCCATCCACACCGCCATCAAGGAAGTCAGCGAAGATCTGGAAAACGATTATCA
ATTCAACACCGCCATTGCCGAGCTGATGAAGCTGAGCAATGCTCTGGGGGAGGCCGGGATCCCGGATTCGCCGGTCTATG
CAGAGGGGATCCGCACGCTGGTGTTGCTGATGGCGCCTTTTGCCCCCCATATTGCGGAGGAGCTGTGGCAGGCGCTGGGG
GGCGCAGACTCGGTGCATCGGCAGTCTTGGCCCAGCTATGACCCGGCAGCGCTGGTGGCCGACACGGTGACCATTGTGAT
TCAGGTGAACGGCAAATTGCGCGGCTCGTTTGAGGCCCCTGCCGAGGTAACGCCGGAGGAGCAGGAACAGTTGGCCCTTC
GGTCAGAAGCAGCGCAGAAATACCTGGAGGGGGCAACACCCAAAAAAGTGGTGGTGGTGCCGAAAAAGCTGGTTAACTTT
GTCCTCTAA

Protein sequence :
MDARYNPQAIESKWQAHWREIGLDRTPELKDGSRKFYALSMFPYPSGNLHMGHVRNYTITDVIARHKRMQGYAVLHPMGW
DAFGLPAENAAIDRGIPPAKWTYQNIAQMREQLQRLGLSYDWEREITTCAPDYYKWTQWLFLQFFKAGLAYQKEAPVNWD
PVDQTVLANEQVDAEGRSWRSGALVEKRMLKQWFFKITAYADQLLADLEKLSGWPERVRTMQENWIGQSVGAKVIFKTEA
GDELAVFTTRPDTLWGATFMVMSPEHPLVDKLTTAEQLQAVRAYQAQAAARSEIERSAEDREKTGVWTGSYAINPVNQER
IPIWIADYVLMGYGTGAIMAVPAHDQRDFEFARKFGLPIKRVVQPPEGSLSSTDRASGTESSELQAAWTGEGVMINSGPL
DGIPVGKGPGQSVERAIAWLEAQGLGEKQINYRLRDWLISRQRYWGCPIPVIHCPHCGIVPVPEKDLPVLLPEDVELTGR
GGSPLAQLEDWVKVKCPTCGAEARRETDTMDTFICSSWYFLRFSDARNDREIFRKDRVNAWLPVDQYVGGIEHAILHLLY
SRFFTKVLRDRGLLDFDEPFLRLLTQGMVQGRTYYNPNKSGKDRWIPAALVKDPDNPTDPETGEPLEVIYATMSKSKGNG
VDPEEVLAHYGADTARMFILFKAPPEKDLEWDDADVEGQFRFLNRVWRQVYEFVVRGGGTESWRGRVSELLPAKVEVGSL
TKAEKDLRRAIHTAIKEVSEDLENDYQFNTAIAELMKLSNALGEAGIPDSPVYAEGIRTLVLLMAPFAPHIAEELWQALG
GADSVHRQSWPSYDPAALVADTVTIVIQVNGKLRGSFEAPAEVTPEEQEQLALRSEAAQKYLEGATPKKVVVVPKKLVNF
VL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-167 45