Gene Information

Name : CYB_0249 (CYB_0249)
Accession : YP_476510.1
Strain : Synechococcus sp. JA-2-3B'a(2-13)
Genome accession: NC_007776
Putative virulence/resistance : Resistance
Product : DNA-binding response regulator RpaA
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 264506 - 265258 bp
Length : 753 bp
Strand : +
Note : identified by similarity to GB:AAD30120.2; match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence :
ATGGCTCGCATACTCATTATTGAGGACGACCCTTCGATTCTGGATATCCTGCGCATCAATCTGGAGTTGGCGGGCTACGA
GGTTGTGAAGGCCACCGATGGGGTGCGCGGACAAGCACTGGCTCTGCAAGTTCTCCCCGATCTGATCATCCTCGACCTGA
TGCTGCCCCAGGTAGATGGCCTGACCGTTTGTCAGCGCTTGCGGCGGGAGGAGCGCACCAGCGAGATCCCGATTTTGATG
CTCACCGCCCTCGGCCAAACCCAGGACAAGATCGAGGGCTTTAATGCCGGTGCCGACGACTACCTGACCAAGCCTTTTGA
GGTGCAGGAGCTGCTGGTGCGGGTGCGGGCCCTGCTGCGTCGCTCAGACCGGATCCCACAGGCGGCCAAGCATGGGGAGA
TCCTCACCTATGGCCCTCTCACGCTGGTGCCGGAGCGCTTTGAGGCGTTGTGGTTCGGCAAAACGATCAAGCTCACCCAC
CTGGAGTTTGACCTGCTCCACTGTCTGATGCAGCGACATGGGCAGACCGTTTCCCCCAGCGAAATCCTGCAGGAGGTGTG
GGGCTACGAGCCCGACGACGACATCGAGACCATCCGTGTTCACATCCGCCACCTGCGCACCAAGCTGGAGCCGGATCCCC
GCCACCCCCAGTACATCAAAACCGTCTATGGGGCGGGCTACTGTCTGGAGTTGCCCAACATTGCCGATCCCGTCCCACCG
CAGCCAGAGCTGGCGAAAGATTCCCACAAATAA

Protein sequence :
MARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDGLTVCQRLRREERTSEIPILM
LTALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLRRSDRIPQAAKHGEILTYGPLTLVPERFEALWFGKTIKLTH
LEFDLLHCLMQRHGQTVSPSEILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPVPP
QPELAKDSHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 4e-20 42
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-17 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-16 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_002952.2859905.p0 Protein 3e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_002745.1124361.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_009782.5559369.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_002951.3237708.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_003923.1003749.p0 Protein 4e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_002758.1121668.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_007622.3794472.p0 Protein 3e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_009641.5332272.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_013450.8614421.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_007793.3914279.p0 Protein 5e-30 44
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA NC_012469.1.7685629. Protein 3e-29 43
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA AE016830.1.gene2255. Protein 2e-20 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA U35369.1.gene1.p01 Protein 2e-20 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA BAC0125 Protein 2e-21 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA AF155139.2.orf0.gene Protein 5e-24 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA HE999704.1.gene2815. Protein 2e-30 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA BAC0197 Protein 6e-19 41
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA AE016830.1.gene1681. Protein 3e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA VFG0596 Protein 2e-17 42
CYB_0249 YP_476510.1 DNA-binding response regulator RpaA VFG1390 Protein 9e-26 41