Gene Information

Name : lysS (CYB_1514)
Accession : YP_477743.1
Strain : Synechococcus sp. JA-2-3B'a(2-13)
Genome accession: NC_007776
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1587285 - 1588820 bp
Length : 1536 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCACTCTCCCCAGCAGCAGCGAAGCCGCCCAACGGGCCGCCCGCCTGGAAAAAGCCCAACACCTGCGGGAACAAGG
GATCCCGCCCTATGCCTATTCTTTTCCTGTTACCCATCTGGCTGCCGAGCTGCAGGAGCAATTTGCCGACCTAGAGCCCG
GCGGCGAGCGGGAGGATGTGCAGGTGGCGGTGGCCGGGCGGATCCGGGCGCGGCGGGTCATGGGCAAGCTGGCTTTCTTT
ACCCTTCAGGATCGCTCCGGCACCATTCAGCTTTATCTAGACAAGAAACGGCTGACGGAGCAGATGGGGGAGCTGGCCTT
CAAGAACCTGGACAAGCTCATCGACGTTGGCGATTGGCTGGGGGCCAAGGGCTGCCTGAAGCGTACCGAAAAAGGGGAAT
TGTCGGTGCGGGTGGATGAATACCAAGTGCTGACCAAGGCCCTGCTGCCGCTGCCGGACAAGTGGCACGGCCTGCGGGAT
GTGGAGAAACGCTACCGCCAGCGCTACGTCGATCTCATCGTCAACCCTGAGGTCAAGCAGACCTTGCTCGACCGCGCCCA
GATCATCCGCTCCCTGCGGCAGACTCTGGAAGAGCGAGGTTTTGTGGAAATTGAGACGCCAGTGTTGCAGGTGATCCCCG
GCGGGGCGGAGGCGCGGCCTTTTGTTACCCACCACAACGCCCTGGATCTGGATCTCTACTTGCGCATTGCCACCGAGCTG
CACCTGAAGCGGCTGGTGGTGGGCGGGATCGAGCGAGTCTATGAAATTGGGCGGGTCTTTCGCAACGAAGGCATCTCCAC
CCGCCACAACCCGGAGTTCACCTCTCTAGAGGCCTATCAAGCCTTCGCCGACTACCACACCATGATGGAGCTGACGGAAA
CCCTGGTCTGCAACGCCGCCCTGGCGGTGCGGGGATCCCTGCAGCTCACCTACCAAGGGGAAGCCATCGACCTCACCCCT
CCCTGGCGACGGGTGACGATGCAGGAGCTGGTGGAGGAGGCCACTGGCATTTTCATCGATGTGGAAAAGGGATGCCCTGA
AGAGCTCTTGCCGGCCTTGGCCGCCCAAGGGATCCCCGATCTCTCCCCCCAGGACTCCCCCGGCCAGTTGCTGGTCAAAG
CCTTTGAGCACTGCTGCGAGAGCCGCCTGCGCCAGCCCACCTTTGTTCTGGACTATCCCCTGGAGGTGTGTCCCCTCACC
AAGCCCCACCGCAGCAAACCGGGGTTGGCCGAGCGCTTCGAGCTGTTCATCGTTGGGCGGGAGACGGCCAACGCCTACTC
CGAGCTCACCGATCCGGTGGATCAGCGGCAGCGGCTGGAGGCCCAGGCAGCCCTGAAGGCAGCCGGCGATGAAGAGGCCC
ATTTTCTGGATGAAGACTTTCTCACCGCCTTGGAATATGGCCTGCCCCCCACAGGTGGCCTGGGCGTGGGGATCGACCGC
TTGGTGATGCTGCTGTGCGACGCTCCCAGCATTCGCGATGTCATTGCCTTTCCGCTGCTGCGGCCCGAGACGGGAGAAGT
GGCGGAGGAGGCTTGA

Protein sequence :
MSTLPSSSEAAQRAARLEKAQHLREQGIPPYAYSFPVTHLAAELQEQFADLEPGGEREDVQVAVAGRIRARRVMGKLAFF
TLQDRSGTIQLYLDKKRLTEQMGELAFKNLDKLIDVGDWLGAKGCLKRTEKGELSVRVDEYQVLTKALLPLPDKWHGLRD
VEKRYRQRYVDLIVNPEVKQTLLDRAQIIRSLRQTLEERGFVEIETPVLQVIPGGAEARPFVTHHNALDLDLYLRIATEL
HLKRLVVGGIERVYEIGRVFRNEGISTRHNPEFTSLEAYQAFADYHTMMELTETLVCNAALAVRGSLQLTYQGEAIDLTP
PWRRVTMQELVEEATGIFIDVEKGCPEELLPALAAQGIPDLSPQDSPGQLLVKAFEHCCESRLRQPTFVLDYPLEVCPLT
KPHRSKPGLAERFELFIVGRETANAYSELTDPVDQRQRLEAQAALKAAGDEEAHFLDEDFLTALEYGLPPTGGLGVGIDR
LVMLLCDAPSIRDVIAFPLLRPETGEVAEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-93 47
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-81 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_477743.1 lysyl-tRNA synthetase VFG1668 Protein 2e-93 47