Gene Information

Name : guaA (CYB_1168)
Accession : YP_477406.1
Strain : Synechococcus sp. JA-2-3B'a(2-13)
Genome accession: NC_007776
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1206389 - 1207999 bp
Length : 1611 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGATCCCTTCTGCATCTCCTCCCAGTTCCGGCCTTTCCCCCCTCGAAGTGCAGCGCCAGATGATCGTCATTCTCGATTT
TGGATCCCAGTACTCTGAGCTGATTGCCCGCCGCATTCGCGAAACCCACGTCTATTCGGAAATCCTTTCCTATCGCACCA
CTGCTGAGCAACTGCGGCAACTGCAACCGCAGGGCATTATCCTCTCCGGGGGCCCCAACTCGGTGTATGAGCCAGCCGCT
CCGGTGTGTGACCCCGAGATTTGGAACCTAGGGATCCCGGTTCTGGGGGTGTGCTACGGCATGCAACTCATGGTGCAGCA
GTTGGGGGGCAAGGTGGAAGCAGCCCAGAAGGGGGAATATGGCCGTGCCGCTCTGCACATTTTGGATCCCACCGACCTGC
TCACCAACCTGCCGGAAAACAGCATCATGTGGATGAGCCACGGGGATTCGGTTACCGAACTGCCGCCGGGCTTTCACACC
TTGGCCTCTACCGACAACACCCCCTGTGCCGCCATTGCCGATCCAAGGCGTCGTCTCTACGGGGTGCAATTTCATCCGGA
GGTGGCCCACTCAGAGGCTGGCGCCTTTCTCATCCGCAACTTTGTCTATCACATCTGCGGTTGCGAGCCCACCTGGACAA
CGGCAGCTTTTCTGGAGGAAGCCATTCGAGAGGTACGTGCCCGTGTGGGCAATAAGAAGGTGCTGTTGGCCCTCTCGGGG
GGGGTAGACAGCTCTACTTTGGCTTTTCTGCTGCACAAGGCCATCGGCGACCAGCTCACCTGCGTGTTCATCGACCAAGG
GTTTATGCGCAAGGACGAGCCCCAACGGCTGCTGCGCCTTTTCCAAGAGCAATTTCACATTCCCGTCCACTACGTGGATG
GCCAGGAGCGGTTTCTCCGGCAGTTGCAGGGGGTTACCGATCCCGAAGAAAAACGCAAACGAATTGGGGCAGAGTTTATT
CGCGTGTTTGAGGAAGAATCCCAGCGGCTGGGTCCTTTTGAGTACTTAGCCCAAGGCACTCTCTACCCAGACGTGATCGA
GTCTGCCAATACCCATGTGGATCCGGTTACTGGAGAACGCATTGCCGTCAAGATCAAAAGCCATCACAATGTCGGCGGCC
TGCCCGAAAATCTGCGCTTTAAGCTGGTAGAGCCTTTGCGCAAGCTCTTCAAAGACGAGGTGCGGCAACTGGCCCGCTCT
TTGGGGCTGCCGGAAGAGATTGTGGGCCGCCATCCTTTTCCGGGGCCGGGGCTGGCCATCCGCATTGTAGGCGAGGTTAC
CAAAGAACGGCTGGAAACCCTGCGAGAAGCGGACATGATCGTGCGGCAGGAGATCAACCGCTCCGGCTACTATCCCAAAC
TTTGGCAAGCCTTTGCCGTGCTGCTGCCAGAGGTGCGGTCGGTGGGGGTGATGGGGGATAAGCGCACCTATGCCTGCCCG
GTGGTGGTGCGGCTGGTTACCAGCGAAGACGGTATGACCGCCGATTGGGCGCGAGTTCCCTACGACCTCTTGGCCACCAT
TTCCAACCGCATCGTCAACGAGGTGCCCGGCATCAACCGCGTGGTTTACGACATCACCTCCAAGCCCCCTGGCACCATCG
AGTGGGAGTAG

Protein sequence :
MIPSASPPSSGLSPLEVQRQMIVILDFGSQYSELIARRIRETHVYSEILSYRTTAEQLRQLQPQGIILSGGPNSVYEPAA
PVCDPEIWNLGIPVLGVCYGMQLMVQQLGGKVEAAQKGEYGRAALHILDPTDLLTNLPENSIMWMSHGDSVTELPPGFHT
LASTDNTPCAAIADPRRRLYGVQFHPEVAHSEAGAFLIRNFVYHICGCEPTWTTAAFLEEAIREVRARVGNKKVLLALSG
GVDSSTLAFLLHKAIGDQLTCVFIDQGFMRKDEPQRLLRLFQEQFHIPVHYVDGQERFLRQLQGVTDPEEKRKRIGAEFI
RVFEEESQRLGPFEYLAQGTLYPDVIESANTHVDPVTGERIAVKIKSHHNVGGLPENLRFKLVEPLRKLFKDEVRQLARS
LGLPEEIVGRHPFPGPGLAIRIVGEVTKERLETLREADMIVRQEINRSGYYPKLWQAFAVLLPEVRSVGVMGDKRTYACP
VVVRLVTSEDGMTADWARVPYDLLATISNRIVNEVPGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-141 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-141 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-141 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-128 52