Gene Information

Name : lysS (CYA_0333)
Accession : YP_473816.1
Strain : Synechococcus sp. JA-3-3Ab
Genome accession: NC_007775
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 350698 - 352224 bp
Length : 1527 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCACTCTCCCCAGCAGCAGCGAAGCTGCCCAACGGGCCGCCCGCCTGGAAAAGGCCCGCCACCTGCAGGAGCAAGG
GATCCTGCCCTACGCCTATTCTTTCCCGGTTACCCACTTGGCTGCCGAGTTGCAGGCGCAATTTGCCGATCTCGAGCCCG
GCGCCGAGCGGGAGGATGTGCAGGTGGCGGTGGCCGGGCGGATCCGGGCGCGGCGGGTCATGGGCAAACTGGCCTTCTTT
ACCCTGCAGGATCGCTCTGGCACCATCCAGCTCTACCTGGAAAAGCAACGGCTGACGCAGCACATGGGGGAGCTGGCCTT
CAAGAACCTGGACAAGCTGCTTGACGTGGGCGATTGGCTGGGGGCCAAGGGCTGTCTCAAGCGCACCGAGAAAGGGGAGC
TGTCGGTGCGGGTGGACGAGTACCAGGTGCTGACCAAGGCCCTGCTGCCCCTGCCCGATAAGTGGCACGGCCTACGGGAT
GTGGAGAAACGCTACCGCCAGCGCTACGTTGACCTCATCGTCAACCCCGAGGTCAAGCAAACCTTGCTCGACCGGGCCAA
GATCGTCCGCTCCCTGCGGCAGACCCTGGAGGAGCGGGGCTTTGTGGAGATCGAGACGCCGGTGCTGCAGGTGATCCCCG
GCGGGGCGGAGGCGCGTCCCTTCATCACCCACCACAACGCCCTGGATCTAGATCTCTACTTGCGCATTGCCACCGAGCTG
CACCTGAAGCGGCTGGTGGTGGGCGGGATCGAGCGGGTGTACGAAATTGGGCGAGTCTTTCGCAACGAGGGCATCTCCAC
CCGCCACAACCCGGAGTTTACCTCGCTGGAGGCCTACCAAGCCTTTGCCGACTACCACACGATGATGGAGCTGACCGAAG
CCCTGGTCTGCAACGCCGCCCTGGCAGTGCGGGGATCCCTGCAAATTACTTACCAAGGGGAGACCATTGACCTCACCCCA
CCCTGGCGGCGGGTAACGATCCAGGAGTTGGTGGAGGAGGCCACCGGCATCTTCATCGACGTGGAAAAGGGATCCACCGC
CGAGCTCTTGCCCGCCCTGGCCCAGCAGGGGATCCCCGATCTCTCCCCCCACGACTCCCCTGGCAAGCTGTTGGTCAAAG
CCTTCGAGCACTGCTGCGAGAGCCGCCTGCGCCAGCCGACCTTTGTTCTCGACTATCCCCTGGAGGTGTGTCCGCTCACC
AAGCCCCACCGCAGCAAGCCGGGGTTGGCGGAGCGCTTCGAGCTGTTTATCGTCGGGCGGGAGACGGCCAACGCCTACTC
GGAGCTGACCGACCCGGTGGATCAGCGGCAGCGGCTGGAGGCCCAGGCGGCCCTGAAGGCAGCCGGAGACGAAGAGGCCC
ACTTTTTGGACGAAGACTTCCTCACTGCCCTGGAGTACGGCCTTCCCCCCACCGGTGGCCTGGGCATCGGCATCGACCGT
CTGGCGATGCTGCTGTGCGACGCTGCCAGCATCCGCGATGTCATCGCCTTCCCCCTGCTGCGACCGGAGACGGGAGAAAG
CCCCTGA

Protein sequence :
MSTLPSSSEAAQRAARLEKARHLQEQGILPYAYSFPVTHLAAELQAQFADLEPGAEREDVQVAVAGRIRARRVMGKLAFF
TLQDRSGTIQLYLEKQRLTQHMGELAFKNLDKLLDVGDWLGAKGCLKRTEKGELSVRVDEYQVLTKALLPLPDKWHGLRD
VEKRYRQRYVDLIVNPEVKQTLLDRAKIVRSLRQTLEERGFVEIETPVLQVIPGGAEARPFITHHNALDLDLYLRIATEL
HLKRLVVGGIERVYEIGRVFRNEGISTRHNPEFTSLEAYQAFADYHTMMELTEALVCNAALAVRGSLQITYQGETIDLTP
PWRRVTIQELVEEATGIFIDVEKGSTAELLPALAQQGIPDLSPHDSPGKLLVKAFEHCCESRLRQPTFVLDYPLEVCPLT
KPHRSKPGLAERFELFIVGRETANAYSELTDPVDQRQRLEAQAALKAAGDEEAHFLDEDFLTALEYGLPPTGGLGIGIDR
LAMLLCDAASIRDVIAFPLLRPETGESP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-86 47
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 8e-75 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_473816.1 lysyl-tRNA synthetase VFG1668 Protein 1e-86 47