Gene Information

Name : clpB (CYA_0180)
Accession : YP_473669.1
Strain : Synechococcus sp. JA-3-3Ab
Genome accession: NC_007775
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 176758 - 179400 bp
Length : 2643 bp
Strand : -
Note : identified by similarity to SP:P03815; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724

DNA sequence :
ATGCAGCCCACCAATCCCAACCAATTTACCGAGAAAGCCTGGAGCGCCATTGTCCAATCCCAAGATGTAGCCCGGCGGCA
CCAGCAGCAACAGTTGGAAACCGAGCATTTGCTGATCTCCCTTCTGGATCAAGAGGGGGGTCTCACCCAGACCATTTTGC
AGCGGGCCGGCCTCGATCCGAGGCTGGTGCGGGATAGAGTGGAAAGCTTTATCAACCAGCAGCCCAAGCTGGCGCGGGTG
GATCAGCTCTACCTAGGCCGCGGCCTGGAGACCACGCTGGATCGAGCCGAGGAGTTTCGCAAAGAGTATGGCGATGATTT
TATCTCGGTAGAGCACTTGCTTTTGGGATCCCTGGACGACGAGCGGGTGGGCAAGCGCGTTCTAGCACCCCTGGGCTTGA
CGGTCGAGCGCCTCAAGCCCGTTATCCAACAGGTGCGAGGCAAACAGCGGGTTACCGACAAAAATCCCGAGTCCCGCTAC
GAGGCCCTGGAGCGCTATGGCCGCGACTTGACCAAGGCCGCCCGCGAAGGGAAGCTGGATCCGGTGATTGGGCGGGACGA
CGAGATCCGCCGCGTCATTCAGGTGCTCTCCCGCCGCACCAAAAACAACCCCGTCCTCATCGGCGAGCCGGGTGTGGGGA
AAACCGCCATCGTCGAGGGCCTGGCCCAGCGCATCAACCGGGGAGACGTGCCGGAGTCGCTGAAAAACCGGCGGGTGATC
GCCCTGGATATGGGATCCCTGATTGCCGGCGCCAAGTACCGCGGCGAGTTTGAAGACCGCCTCAAAGCCGTGCTCAAGGA
GGTCACCGAATCGGAAGGGCAGATCATCCTCTTCATCGACGAGCTGCACACCGTGGTGGGGGCAGGGGCGGCCGAAGGGG
CGATGGATGCCGGCAACCTGCTCAAGCCCATGCTGGCCCGCGGCGAATTGCGCTGCATTGGCGCCACCACCCTGGATGAA
TACCGCAAGCACATCGAAAAAGACGCCGCCCTGGAGCGCCGCTTCCAGCCGGTGTATGTGGATCAGCCCTCCGTGGAAGA
CACCATCTCCATCCTGCGCGGCCTCAAAGAGCGCTACGAGCTGCACCACGGGGTCAAAATCAGCGACTCGGCCCTGGTGG
CAGCGGCAGTCCTCTCCAACCGCTACATCTCCGAGCGCTTCCTGCCCGACAAGGCCATCGACCTGGTGGACGAAGCGGCG
GCCAAGCTGAAGATGGAGATCACCTCCAAGCCCGTCGAATTGGATGAAATCGACCGGCGCATCATGCAACTGCAGATGGA
GGAGCTCTCCCTCAAGAAAGAAGACGACCCCGCCTCCAAAGAGCGCCTGGGCAAAATTGAGCAGGAGCTAGCCAACTTGA
TGGAGCGGCAGCGGGAGCTGAGCGCCCGTTGGCAAATGGAAAAAGAGGCCATCGAGCGGCTGCAAAACCTCAAGGCCGAG
CGGGATGCCGTCAAGCTGCAGATTGAACAGGCAGAACAAAAATATGACCTCAACCGCGCTGCCGAGCTCAAATACGGCAA
GCTCATGGAGCTGGAGCGCCAGATCCAAGAGCAGGAGGCCCACCTGGCCAAGCTGCAGGCCAACGGCGAGCCCTTGTTGC
GGGAGCAGGTGACGCCCGAAGACATTGCCGAGATCGTCTCCCGCTGGACCGGGATCCCGGTCACCAGCCTGATGGAGTCG
GAAAAGCAGAAGCTGCTGCGCCTGGAAGCCCACTTGCACCAGCGGGTGGTGGGCCAGGACGAGGCGGTAGCGGCGGTGGC
AGCCGCCATCCGGCGGGCCCGGGCCGGCCTCAAGGATCCCAATCGGCCCATCGGCTCGTTCCTGTTCATGGGGCCCACCG
GCGTCGGGAAGACCGAGCTGGCCCGCGCCCTGGCGGAGTTCCTCTTCGACACCTCCGAGGCCATGGTGCGCATCGACATG
TCGGAGTACATGGAGAAGCACTCCGTCTCCCGCTTGATTGGGGCTCCGCCGGGCTATGTGGGCTACGAAGAAGGCGGGCA
GCTCTCGGAAGCGGTGCGGCGGCGCCCCTACTCGGTGGTGCTCTTTGACGAGGTGGAAAAAGCCCACCCTGATGTCTTCA
ACATCCTGCTGCAGGTGCTGGACGACGGCCGCATCACCGACTCCCAAGGCAGGACGGTGGACTTCAAAAACACCATCATC
ATCATGACCAGCAACATTGGCAGCGAGCTCATCCTGGAAATTGGCGGCGACGAGAGCCGCTACGAGGAGATGAAAAGCCA
GGTGCTGGCCATGCTGCGGCACCACTTCCGGCCGGAGTTCCTCAACCGGGTGGATGAACTGATCATCTTCCACGCTCTAA
CCAAAGAGCAAATCCGCCAGATCGTCAGCCTGCAGATGCGGCGGGTGGAGCAGTTGCTGGCGGATCAGCAAATTGAAATT
GTCCTCACCGAAGAGGCCAAGGACTACCTGGCCGAGCTGGGCTACGACCCCGTGTTTGGCGCCCGCCCGCTGAAGCGGGT
AATCCAGCGGGAGATCGAAAACCCCCTCGCCACCAAGCTGCTGGAAAACGAGTTCCTGCCCGGCGACCGCATCCTGGTGG
AGGTGGCCAACGAGCGGCTGATCTTCCGCAAGATCGGCTCTCAGCCCCGCCAAGAGCCGCCTGCTGCTGTAGCCGTCAGC
TAG

Protein sequence :
MQPTNPNQFTEKAWSAIVQSQDVARRHQQQQLETEHLLISLLDQEGGLTQTILQRAGLDPRLVRDRVESFINQQPKLARV
DQLYLGRGLETTLDRAEEFRKEYGDDFISVEHLLLGSLDDERVGKRVLAPLGLTVERLKPVIQQVRGKQRVTDKNPESRY
EALERYGRDLTKAAREGKLDPVIGRDDEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRINRGDVPESLKNRRVI
ALDMGSLIAGAKYRGEFEDRLKAVLKEVTESEGQIILFIDELHTVVGAGAAEGAMDAGNLLKPMLARGELRCIGATTLDE
YRKHIEKDAALERRFQPVYVDQPSVEDTISILRGLKERYELHHGVKISDSALVAAAVLSNRYISERFLPDKAIDLVDEAA
AKLKMEITSKPVELDEIDRRIMQLQMEELSLKKEDDPASKERLGKIEQELANLMERQRELSARWQMEKEAIERLQNLKAE
RDAVKLQIEQAEQKYDLNRAAELKYGKLMELERQIQEQEAHLAKLQANGEPLLREQVTPEDIAEIVSRWTGIPVTSLMES
EKQKLLRLEAHLHQRVVGQDEAVAAVAAAIRRARAGLKDPNRPIGSFLFMGPTGVGKTELARALAEFLFDTSEAMVRIDM
SEYMEKHSVSRLIGAPPGYVGYEEGGQLSEAVRRRPYSVVLFDEVEKAHPDVFNILLQVLDDGRITDSQGRTVDFKNTII
IMTSNIGSELILEIGGDESRYEEMKSQVLAMLRHHFRPEFLNRVDELIIFHALTKEQIRQIVSLQMRRVEQLLADQQIEI
VLTEEAKDYLAELGYDPVFGARPLKRVIQREIENPLATKLLENEFLPGDRILVEVANERLIFRKIGSQPRQEPPAAVAVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-100 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-98 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_473669.1 ATP-dependent chaperone protein ClpB VFG2076 Protein 2e-114 44
clpB YP_473669.1 ATP-dependent chaperone protein ClpB VFG2084 Protein 4e-104 43