Gene Information

Name : guaA (CYA_1673)
Accession : YP_475092.1
Strain : Synechococcus sp. JA-3-3Ab
Genome accession: NC_007775
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1673291 - 1674907 bp
Length : 1617 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAACTCTTCTACCTCTCCCCTCCCTCCCGGCCTTTTTCCTTCCTCCCTCAAGGTGCAGCGCCAGATGATTGTTATTCT
CGATTTTGGATCCCAGTACTCTGAGCTCATTGCCCGGCGTATTCGCGAAACCCACGTCTATTCGGAAATCCTTTCCTACC
GCACCACTGCCGAGCAACTGCGGCAACTGCGGCCCCAGGGCATCATCCTCTCCGGCGGCCCCAACTCGGTCTATGAGCCG
GGCGCTCCCGCTTGTGACCTGGAGATCTGGAACTTGGGGATCCCCATCCTGGGCGTGTGCTACGGTATGCAGCTTATGGT
GCAGCAGTTGGGGGGCAAGGTGGAGCCGGCCCAGAAGGGGGAATACGGCCGTGCCGCCCTGCACATTTTGGATCCCACCG
ATCTGCTCACCAACCTGCCAGAAAGCAGCATCATGTGGATGAGCCACGGAGACTCGGTGACCGAGTTGCCCCCGGGCTTT
CATTCGCTGGCTTACACTGACAACACCCCCTTTGCCGCCATTGCCGATCCGGCGCGCCGTCTCTACGGGGTGCAATTTCA
CCCAGAGGTGGCCCACTCGGAGGCCGGTACCTTTCTCATTCGCAATTTTGTCTATCACATCTGCGGCTGCGAGCCCACCT
GGACAACGGAAGCTTTTCTGGAGGAGGCCATTCGGGAAGTCCGTGCCCGCGTGGGCGACAAGAGGGTGCTGTTGGCCCTT
TCGGGGGGGGTGGACAGCTCTACTTTGGCTTTTCTGCTACACAAGGCCATTGGGGATCAGCTCACCTGCGTGTTCATCGA
CCAGGGGTTCATGCGCAAAGATGAGCCGCAGCGGCTGCTGCGCCTTTTCCAAGAGCAATTTCACATCCCTGTCCACTACG
TGGACGGACAAGAGCGCTTTCTCCGCCAGTTGCAGGGGGTCACCGATCCCGAGGAGAAGCGCAAACGCATCGGGGCAGAG
TTTATTCGCGTGTTTGAGGAGGAGTCGCAGCGGCTGGGCCCCTTCGAGTACCTGGCCCAGGGCACCCTTTACCCCGATGT
GATCGAGTCGGCCAACACCAATGTGGATCCGGTTACCGGAGAGCGCATTGCCGTCAAGATCAAAAGCCACCACAACGTCG
GCGGCTTGCCGGAGAATCTGCGCTTTAAGCTGGTAGAACCTCTGCGCAAGCTCTTCAAAGATGAGGTACGGCAACTGGCC
CGTTCGTTGGGCTTGCCGGAAGAAATTGTTGGCCGCCATCCTTTCCCGGGGCCGGGCCTGGCCATCCGCATTGTGGGCGA
GGTCACCAAAGAGCGGCTGGAGATCCTGCGCGAGGCCGACATGATTGTCCGCCAGGAGATCAACCGCTCCGGCTACTATC
CCAAGCTGTGGCAAGCCTTTGCCGTGTTGCTGCCGGAAGTGCGCTCGGTGGGGGTGATGGGGGATAAGCGCACCTATGCC
TGCCCGGTGGTGGTGCGACTGGTCACCAGCGAAGACGGCATGACGGCGGACTGGGCTAGGGTGCCCTACGACCTCTTGGC
CACCATCTCCAACCGCATCGTCAACGAGGTGCCGGGCGTCAACCGCGTAGTCTACGACATCACCTCCAAGCCCCCCGGCA
CCATCGAGTGGGAGTGA

Protein sequence :
MNSSTSPLPPGLFPSSLKVQRQMIVILDFGSQYSELIARRIRETHVYSEILSYRTTAEQLRQLRPQGIILSGGPNSVYEP
GAPACDLEIWNLGIPILGVCYGMQLMVQQLGGKVEPAQKGEYGRAALHILDPTDLLTNLPESSIMWMSHGDSVTELPPGF
HSLAYTDNTPFAAIADPARRLYGVQFHPEVAHSEAGTFLIRNFVYHICGCEPTWTTEAFLEEAIREVRARVGDKRVLLAL
SGGVDSSTLAFLLHKAIGDQLTCVFIDQGFMRKDEPQRLLRLFQEQFHIPVHYVDGQERFLRQLQGVTDPEEKRKRIGAE
FIRVFEEESQRLGPFEYLAQGTLYPDVIESANTNVDPVTGERIAVKIKSHHNVGGLPENLRFKLVEPLRKLFKDEVRQLA
RSLGLPEEIVGRHPFPGPGLAIRIVGEVTKERLEILREADMIVRQEINRSGYYPKLWQAFAVLLPEVRSVGVMGDKRTYA
CPVVVRLVTSEDGMTADWARVPYDLLATISNRIVNEVPGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-141 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-141 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-141 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-128 51