Gene Information

Name : leuS (CYA_1256)
Accession : YP_474702.1
Strain : Synechococcus sp. JA-3-3Ab
Genome accession: NC_007775
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1270024 - 1272645 bp
Length : 2622 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGACGCGCGCTACAATCCTCCGGCCATCGAAAGCAAGTGGCAGGCCCACTGGCGTGAACTCGGGTTGGATCGCACGCC
GGAGCTGACGGCGGAAAGCCGCAAGTTTTATGCCCTGTCGATGTTCCCCTACCCCAGTGGCAGCCTGCACATGGGGCATG
TGCGTAATTACACCATCACGGATGTGATTGCCCGCCACAAGCGGATGCAGGGGTACGCGGTGCTGCACCCCATGGGGTGG
GATGCCTTTGGCTTGCCGGCAGAGAACGCCGCCATCGATCGGGGGATCCCGCCGGCCAAGTGGACTTACCAGAACATTGC
CCAAATGCGGGATCAACTGCAGCGGCTGGGGCTTTCCTACGACTGGGAGCGGGAGATCACCACTTGCGCCCCCGACTACT
ACAAGTGGACGCAGTGGCTCTTCCTGCAGTTTTTCAAAGCGGGCCTGGCCTACCAGAAGGAGGCGCCGGTGAACTGGGAT
CCGGTGGACCAGACCGTCTTGGCCAACGAGCAGGTAGATGCGGAAGGGCGCTCCTGGAGATCGGGAGCTCTGGTGGAAAA
GCGCCTCCTCAAGCAGTGGTTTCTCAAGATCACGGCCTATGCCGACCAACTGCTGGCTGACCTGGAGAAGCTCTCCGGCT
GGCCGGAGCGGGTGCTCACCATGCAGGAGAACTGGATTGGCCAGTCGGTGGGGGCTAGGGTTGTCTTCAAAACCGAAACA
GGGGAGGAGCTGCCGGTGTTCACCACCCGGCCTGACACCCTCTGGGGAGCCACCTTCATGGTGCTGGCGCCGGAGCATCC
CTTGGTGGAGAAGCTCACCACCCCTGAGCAAGAGGTTGCCGTCAAGGCCTACCGGGCCGAGGCCGCTGCCCGCAGCGAGA
TCGAGCGCAGCGCCGAAGACCGCGAAAAAACGGGCGTCTGGACGGGATCCTACGCCATCAACCCCGTCAATCAAGAGCGG
ATCCCCATCTGGATTGCCGACTATGTGCTCATGGGCTACGGCACAGGAGCCATCATGGCCGTGCCCGCCCACGACCAGCG
GGACTTTGAGTTTGCCCGCCAGTTCGGCCTGCCCATCAAGCTGGTGGTGCAGCCGCCCCAAGGGGGGGTGACGAGTGCTG
AAGATCTGCAGGCGGCCTGGACGGGGGAGGGGGTGTTGATCAACTCCGGCCCCTTGAACGGAATCCCAGTGGGCAAGGGC
CCAGGGCAAAGTGTAGAAAGGGCCATCGCCTGGCTAGAAGAGCAGGGGCTGGGAGAACGGCAGGTCAACTACCGCCTGCG
GGATTGGCTCATCTCGCGACAGCGCTACTGGGGCTGCCCCATTCCCATCATCCACTGCCCCCACTGCGGCATTGTGCCGG
TGCCGGAGGAGGATCTGCCGGTGCTGTTGCCCGAGGATGTGGAGCTGACGGGGCGAGGGGGATCCCCCTTGGCCCAGTTG
GAGGACTGGGTAAAGGTGAAGTGCCCCGCCTGTGGTGCCGACGCCCGCCGCGAGACGGACACGATGGACACCTTTATCTG
CTCCTCGTGGTATTTCCTGCGCTTTAGCGATCCCCGCAACGACCGCGAGATCTTCCGCAAGGATCTGGTCAACGCCTGGC
TGCCGGTAGATCAGTACGTGGGCGGCATCGAGCACGCCATCTTGCACCTGCTTTACTCCCGTTTTTTCACCAAAGTGCTG
CGGGATCTGGGGTTGTTGAATTTCGATGAGCCCTTCTCCCGCCTGCTAACCCAGGGGATGGTGCAGGCGCGCACCTACTA
CAACCCCAACAAGTCCGGCAAGGATCGCTGGATCCCTACTGCATTGGTCAAGGATCCCAACGACCCGCGGGATCCGGAAA
CCGGCGAGCCCCTGCAGGTTATCTACGCAACTATGTCCAAGTCCAAGGGCAACGGCGTGGATCCGGAAGAGGTGCTGGCC
AACTACGGGGCAGACACAGCCCGCATGTTCATCCTCTTCAAGGCGCCGCCGGAAAAGGACTTGGAGTGGGACGATGCCGA
TGTGGAAGGGCAGTTTCGCTTTCTCAACCGCGTCTGGCGGCAGGTGTACGAGTTTGTTGTTCGCGGTAGCGGGACGGAGT
CCTTGCAGGGCAAAGCCGCCGAGCTGCTGCAGGCCAAGGTTGAAGCAGGATCCCTGACCAAAGCGGAAAGGGATCTGCGC
CGCGCCGTGCACACGGCCATCAAAGAAGTCAGCGAGGACTTGGAGGAGTACCAGTTCAACACTGCCATTGCTGGGCTGAT
GAAGCTGAGCAACGCCCTGGCTGAAGCCGAGATCCCGGACTCGCCAGTCTATGCGGAAGGGATCCGCACCTTGGTCTTGC
TCCTAGCCCCCTTTGCCCCCCACATGGCTGAGGAGCTGTGGCAGGCCCTGGGCGGCACCGACTCAGTGCATCGCCAGGCT
TGGCCTACCTATGACCCGGCGGCCCTAGTGGCCGATACGGTAACGATTGTGGTGCAGGTCAACGGCAAGCTGCGCGGCTC
CTTTGAAGCCCCTGCCGATGTCACGCCCCAGGAGCAGGAGCGGTTGGCTCTGCAATCGGAGGCGGCGCAGAGGTATCTGC
AAGGGATGACGCCGAAGAGGGTCATTGTGGTGCCGAAGAAGCTGGTTAACCTGGTTGTCTAA

Protein sequence :
MDARYNPPAIESKWQAHWRELGLDRTPELTAESRKFYALSMFPYPSGSLHMGHVRNYTITDVIARHKRMQGYAVLHPMGW
DAFGLPAENAAIDRGIPPAKWTYQNIAQMRDQLQRLGLSYDWEREITTCAPDYYKWTQWLFLQFFKAGLAYQKEAPVNWD
PVDQTVLANEQVDAEGRSWRSGALVEKRLLKQWFLKITAYADQLLADLEKLSGWPERVLTMQENWIGQSVGARVVFKTET
GEELPVFTTRPDTLWGATFMVLAPEHPLVEKLTTPEQEVAVKAYRAEAAARSEIERSAEDREKTGVWTGSYAINPVNQER
IPIWIADYVLMGYGTGAIMAVPAHDQRDFEFARQFGLPIKLVVQPPQGGVTSAEDLQAAWTGEGVLINSGPLNGIPVGKG
PGQSVERAIAWLEEQGLGERQVNYRLRDWLISRQRYWGCPIPIIHCPHCGIVPVPEEDLPVLLPEDVELTGRGGSPLAQL
EDWVKVKCPACGADARRETDTMDTFICSSWYFLRFSDPRNDREIFRKDLVNAWLPVDQYVGGIEHAILHLLYSRFFTKVL
RDLGLLNFDEPFSRLLTQGMVQARTYYNPNKSGKDRWIPTALVKDPNDPRDPETGEPLQVIYATMSKSKGNGVDPEEVLA
NYGADTARMFILFKAPPEKDLEWDDADVEGQFRFLNRVWRQVYEFVVRGSGTESLQGKAAELLQAKVEAGSLTKAERDLR
RAVHTAIKEVSEDLEEYQFNTAIAGLMKLSNALAEAEIPDSPVYAEGIRTLVLLLAPFAPHMAEELWQALGGTDSVHRQA
WPTYDPAALVADTVTIVVQVNGKLRGSFEAPADVTPQEQERLALQSEAAQRYLQGMTPKRVIVVPKKLVNLVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-164 46