Gene Information

Name : guaA (RHE_CH00297)
Accession : YP_467846.1
Strain : Rhizobium etli CFN 42
Genome accession: NC_007761
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 303945 - 305507 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCACATCCCGACTCCGTTCTCATCGTCGATTTCGGCAGCCAGGTGACCCAGCTCATCGCACGGCGCGT
GCGCGAGGCCGGCGTCTATTGCGAGATCGTTCCCTTTCAATCTGCCGAAGAAGGCTTCAAGCGCCTACAGCCGAAGGCCG
TGATCCTCTCCGGCAGCCCGGCTTCCACCGTGGACGAGGGATCGCCGCGAGCGCCTCAGATCATCTTCGACAGTGGCCTG
CCGGTCTTCGGCATCTGCTACGGTCAGCAGACGATGTGCATGCAGCTCGGCGGCAAGGTCGAAAGCGGCCATCACCGTGA
ATTCGGACGCGCCTTTCTGGATGTCGACAAGGATTGCGAGCTGTTCGAAGGCCTCTGGTCCTCCGGCTCGCGCCATCAGG
TGTGGATGAGCCATGGCGACCGCGTCACCGCGCTGCCCGATGGTTTCAAGGTGGTCGCCACCTCTTCCAATGCGCCCTTC
GCCTTCATCGCCGACGAGAAGCGCAAATATTACGGCGTGCAATTCCACCCCGAGGTCGTCCATACGCCTGACGGCGCCAA
GCTGATCGGCAACTTCATTCACAATGTCGCTGGAATCAAGGGCGACTGGTCGATGTCGGCCTATCGCCAAAAGGCGGTCG
AAGAGATCCGCAAGCAGGTGGGCGACAAGCGCGTCATCTGCGCGCTTTCGGGCGGCGTCGACAGCTCCGTCGCAGCGCTC
CTGATCCACGAGGCCGTCGGCGACCAGCTGACCTGCATCCTCGTCGACCACGGCCTGATGCGGAAGGACGAGGCGGCCAA
TGTCGTCGCCATGTTCCGCGAGCACTACAATCTGCATCTGCTGCACGTCGATGCCTCGGACCGCTTCATCGGCGAGCTCG
AAGGCGTCAGCGACCCGGAAACCAAGCGCAAGATCATCGGCCGGCTCTTCATCGAGACCTTCGAGGAAGAGGCAAAGAAA
CTCGGCGGCGCCGATTTCCTCGGCCAGGGCACGCTCTATCCTGACGTGATCGAGAGCGTTTCCTTCACCGGCGGCCCGTC
GGTGACGATCAAGTCGCACCATAATGTCGGCGGCCTGCCGGAACGCATGAAGATGCAGCTCGTCGAGCCGCTGCGCGAAC
TCTTCAAGGACGAGGTGCGCGCGCTCGGCCGTGAACTCGGCCTGCCCGACAGCTTCATTGGCCGTCATCCCTTCCCCGGC
CCCGGCCTTGCCATCCGTTGCCCCGGCGGCATCACCCGCGAGAAGCTCGAGATCCTGCGCGAGGCCGATGCGATCTATCT
CGACGAAATCCGCAAGGCCGGCCTCTACGACGCCATCTGGCAGGCCTTCGCCGTGCTGCTCCCGGTCCAGACCGTCGGCG
TCATGGGCGACGGGCGCACCTATGAATTCGTCTGCGCGCTGCGCGCCGTCACCTCCGTCGACGGCATGACCGCCGATTTC
TACCACTACGACATGGAATTCCTCGGCCGCGCCGCCACCCGCATCATCAATGAGGTGCGCGGCATCAACCGTGTGGTCTA
TGATGTCACGTCAAAGCCGCCCGGCACCATCGAGTGGGAGTGA

Protein sequence :
MTQTAHPDSVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFKRLQPKAVILSGSPASTVDEGSPRAPQIIFDSGL
PVFGICYGQQTMCMQLGGKVESGHHREFGRAFLDVDKDCELFEGLWSSGSRHQVWMSHGDRVTALPDGFKVVATSSNAPF
AFIADEKRKYYGVQFHPEVVHTPDGAKLIGNFIHNVAGIKGDWSMSAYRQKAVEEIRKQVGDKRVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAANVVAMFREHYNLHLLHVDASDRFIGELEGVSDPETKRKIIGRLFIETFEEEAKK
LGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPG
PGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-137 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-137 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-116 50