Gene Information

Name : tetA (RHE_CH01023)
Accession : YP_468560.1
Strain : Rhizobium etli CFN 42
Genome accession: NC_007761
Putative virulence/resistance : Resistance
Product : tetracycline efflux transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 1074761 - 1076080 bp
Length : 1320 bp
Strand : -
Note : similar to tetA (AGR_L_1300p) [Agrobacterium tumefaciens] and TetA [Escherichia coli]; Similar to swissprot:Q7CUB3; location:bacterial inner membrane Psort-Score: 0.4652

DNA sequence :
ATGCGCTTCAGCCATGGTTCGGCCAGCACCTCCCTGAAACCAACGCCTGACCAGATCAGGCCTCATCGTGAGCCATCGGC
GCACTCTGTCGGCGCTCGTGCGCTCGCGTCGACCCGGAACGCACCCATGACAAGATCCCTTATCGTCATCTTCACCGCCA
TTGTCCTCGATGCCGTCGGCATCGGGCTGATTTTCCCGATCCTGCCGTCGCTGCTGCAGGAGATCACCCATGCCCAAAAC
GTCGCGCCCACGATCGGCGCGATGACGGCGCTCTACGCGCTGATGCAGTTCATCTTCGCCCCGGTGCTCGGGGCGCTGAG
CGACCGGCTCGGCCGCCGCCCGGTGCTGCTGATTTCGCTGGCCGGCGCGGCCGTCAACTATCTCTTCCTCGCCTTCGCGC
CCAATCTGACCCTGCTCTTCGTCGGCCGGGCGATCGCCGGGCTGACGAGCGCCAATATCTCGGTGGCGACAGCCTATATC
ACCGATATCTCGCCGGAGGAGAAACGCGCCCGCCGCTTCGGCCTGTTCAACGCCATGTTCGGCCTCGGCTTCATCATCGG
CCCGGTCGCCGGCGGCGTGCTCGGCGATCATTGGCTGCGGCTGCCCTTCATCGCAGCCGCCGTGCTCAACGGCGCCAACC
TGCTGCTCGCCGTCTTCATCCTGCCGGAATCGCGCCCGGGCAGCCGCGAGACGATCGATCTGGCGGCGCTCAATCCGCTC
AAACCGCTGCGCTCGGTGCTGGAGGTCAAAAGCCTGCTGCCGATCGTCATCCTGTTCTTCATCTTCAGCGCCACCGGCGA
GGCCTATGGCACCTGCTGGGCGCTCTGGGGCAGCGACGCCTTCCACTGGAACGGGCTGTCGATCGGCCTTTCGCTGGGCG
CCTTCGGCATCTGCCAGACGCTCGCCCAGGCGCTGCTGCCCGGACCGGCCGTCAGGCTGCTCGGTGAGCGCGCCGCGATC
CTCGTGGGTGTTGCCGGCGTTTCACTCGCGCTCACCGTCATGGCCTTTGCCGGCCAGGGCTGGATGATCTTCGCCGTCAT
GCCGATCTTCACCCTCGGCGGCATCGGCGTACCGGCGCTGCAATCGCTCGCCACCCGGCAGGTCGACGAGAACAGTCAGG
GCCAGTTCCAGGGCGTGCTGGCCTCAGTCGTCAGCCTCGCCTCGATCGCAGCACCGCTCGGCTTTTCCAGCCTCTATTTC
CTCGTCCGAGAGGAATGGCCGGGCGCCATCTGGCTATCGGTCGTCGCCGTCTACGCGCTCACCGTGCCGCTGGTGCTCGG
GTTGCGGCTGAAGACGGCGGAGCGGGCGGCGGTGAGTTAG

Protein sequence :
MRFSHGSASTSLKPTPDQIRPHREPSAHSVGARALASTRNAPMTRSLIVIFTAIVLDAVGIGLIFPILPSLLQEITHAQN
VAPTIGAMTALYALMQFIFAPVLGALSDRLGRRPVLLISLAGAAVNYLFLAFAPNLTLLFVGRAIAGLTSANISVATAYI
TDISPEEKRARRFGLFNAMFGLGFIIGPVAGGVLGDHWLRLPFIAAAVLNGANLLLAVFILPESRPGSRETIDLAALNPL
KPLRSVLEVKSLLPIVILFFIFSATGEAYGTCWALWGSDAFHWNGLSIGLSLGAFGICQTLAQALLPGPAVRLLGERAAI
LVGVAGVSLALTVMAFAGQGWMIFAVMPIFTLGGIGVPALQSLATRQVDENSQGQFQGVLASVVSLASIAAPLGFSSLYF
LVREEWPGAIWLSVVAVYALTVPLVLGLRLKTAERAAVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 6e-70 48
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 6e-70 48
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 9e-70 48
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 6e-70 48
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 2e-71 47
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 2e-71 47
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 1e-57 44
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 8e-56 44
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 8e-56 44
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 8e-56 44
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 8e-56 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetA YP_468560.1 tetracycline efflux transporter NC_011586.7043399.p0 Protein 8e-103 62
tetA YP_468560.1 tetracycline efflux transporter NC_011595.7059241.p0 Protein 2e-103 62
tetA YP_468560.1 tetracycline efflux transporter NC_010410.6003291.p0 Protein 3e-103 62
tetA YP_468560.1 tetracycline efflux transporter NC_009085.4918440.p0 Protein 2e-96 60
tetA YP_468560.1 tetracycline efflux transporter AF090987.gene.p01 Protein 2e-73 51
tetA YP_468560.1 tetracycline efflux transporter Y19114.gene.p01 Protein 3e-71 49
tetA YP_468560.1 tetracycline efflux transporter AY264780.2.gene3.p01 Protein 2e-77 49
tetA YP_468560.1 tetracycline efflux transporter X75761.gene.p01 Protein 1e-68 48
tetA YP_468560.1 tetracycline efflux transporter NC_011586.7045189.p0 Protein 2e-63 47
tetA YP_468560.1 tetracycline efflux transporter CP001485.1.gene2821. Protein 1e-71 47
tetA YP_468560.1 tetracycline efflux transporter NC_010410.6002597.p0 Protein 1e-71 47
tetA YP_468560.1 tetracycline efflux transporter AF534183.gene.p01 Protein 4e-71 47
tetA YP_468560.1 tetracycline efflux transporter AY743590.gene.p01 Protein 1e-73 46
tetA YP_468560.1 tetracycline efflux transporter NC_010410.6002612.p0 Protein 7e-58 44
tetA YP_468560.1 tetracycline efflux transporter AF133140.gene.p01 Protein 7e-58 44
tetA YP_468560.1 tetracycline efflux transporter AF133139.gene.p01 Protein 1e-56 43
tetA YP_468560.1 tetracycline efflux transporter Y19116.gene.p01 Protein 3e-51 42
tetA YP_468560.1 tetracycline efflux transporter AJ420072.gene.p01 Protein 8e-57 42
tetA YP_468560.1 tetracycline efflux transporter L06940.gene.p01 Protein 4e-53 41