Gene Information

Name : guaA (Adeh_2348)
Accession : YP_465555.1
Strain : Anaeromyxobacter dehalogenans 2CP-C
Genome accession: NC_007760
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2649668 - 2651224 bp
Length : 1557 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACATCCACTCAGAGAAGATCCTCATCCTCGACTTCGGGTCGCAGTACACGCAGCTCATCGCGCGGCGGCTGCGCGA
GCTGGGCGTCTACTGCGAGATCCACCCCTGCACCGCGAAGGCGGAGGCGATCCGCGCGTTCCGGCCCCGCGGCGTCGTGC
TCTCCGGCGGCCCCGCCTCGGTGCTCGCCGAGGGCAGCCCGCGCTGCGACCGGGTGGTGTTCGAGCTGGGCGTGCCGGTG
CTGGGCATCTGCTACGGCCTGCAGGTCTTCGCCGCCGAGCTGGGCGGCCGGGTGGACCAGGCGGCGCACCGCGAGTTCGG
CCCCGCCACCATCGAGGTGAAGGCCACCTCGCCGCTGTTCCAGGGCCTGCCGGCCACGCTCGACGTCTGGATGAGCCACG
GCGACCGCGTCGAGGCGCTGCCGCCCGGCTTCGAGCCCATCGCCGCCTCGCCCTCGGCCCCGTTCGCCGCGGTGGAGGAC
CGCGCCCGCCGCTTCTACGGCGTGCAGTTCCACCCCGAGGTCGTCCACACGCCGCGCGGCAAGGACGTGCTCCGCAACTT
CGCCTACGGCGTGTGCGGCTGCTCCGGCACCTGGTCGATGCGCGGCTACGCCGAGGCGGCGGTGGAGCAGATCCGCGCCC
AGGTGAAGGACGGCCACGTCATCTGCGCGCTGTCGGGCGGGGTGGACTCGGCGGTGGCGGCGCTGCTGGTGCACCGGGCC
ATCGGCGACCGGCTGCGCTGCATCTTCGTGGACAACGGCGTGCTCCGCGCCGGCGAGCGCAAGCAGGTCGAGGACGTCTT
CGGCGCGATGTTCCACCTGCCGCTCGTGACCGTGGACGCCTCGCGGCGCTTCCTCGGCGCGCTGGCGGGGGTCACCGACC
CCGAGCGGAAGCGCAAGATCATCGGGCACGAGTTCATCGCGGTGTTCGAGCAGGAGGTGGAGCGGCTCGCGGCGCACGGC
GCGCGCGCGAGGTTCCTGGTGCAGGGCACGCTCTACCCCGACGTGATCGAGTCGGTGTCGTTCCGCGGCCCCTCCGCCAC
CATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGAAGATGAACCTCGCGCTGGTCGAGCCGCTGCGCGAGCTGTTCA
AGGACGAGGTCCGCGAGCTCGGCCTGGAGCTCGGCCTGCCCGAGGCCATCGTGCGGCGCCAGCCGTTCCCGGGCCCCGGC
CTCGCCATCCGCGTGCTCGGCGAGGTCACCGAGGAGCGGCTCTCGGTGCTGCGCCGCGCCGACACCATCGTGCAGGAGGA
GGTCCGCGCCGCCGGCCTGTACGAGAAGCTCTGGCAGGGCTTCGCGGTGCTCCTGCCGGTCCGCAGCGTCGGCGTCATGG
GCGACGAGCGGACCTACGAGTCCACCTGCGCGATCCGCGCGGTGGAGTCCACCGACGGCATGACCGGCGACTGGGCGCGC
CTGCCGTACGACCTGCTGGGCCGCATGTCCTCGCGCATCATCAACGAGGTCCGCGGCATCAACCGCGTGGTCTACGACAT
CTCCTCCAAGCCGCCCGCGACCATCGAGTGGGAATGA

Protein sequence :
MDIHSEKILILDFGSQYTQLIARRLRELGVYCEIHPCTAKAEAIRAFRPRGVVLSGGPASVLAEGSPRCDRVVFELGVPV
LGICYGLQVFAAELGGRVDQAAHREFGPATIEVKATSPLFQGLPATLDVWMSHGDRVEALPPGFEPIAASPSAPFAAVED
RARRFYGVQFHPEVVHTPRGKDVLRNFAYGVCGCSGTWSMRGYAEAAVEQIRAQVKDGHVICALSGGVDSAVAALLVHRA
IGDRLRCIFVDNGVLRAGERKQVEDVFGAMFHLPLVTVDASRRFLGALAGVTDPERKRKIIGHEFIAVFEQEVERLAAHG
ARARFLVQGTLYPDVIESVSFRGPSATIKSHHNVGGLPEKMNLALVEPLRELFKDEVRELGLELGLPEAIVRRQPFPGPG
LAIRVLGEVTEERLSVLRRADTIVQEEVRAAGLYEKLWQGFAVLLPVRSVGVMGDERTYESTCAIRAVESTDGMTGDWAR
LPYDLLGRMSSRIINEVRGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-143 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-143 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-143 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-128 56